Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nicole Legros"'
Autor:
Abdelhamid El Khissiin, Hye-Sook Seo, Gilbert Querton, Denis Larsimont, Ioanna Laïos, Guy Leclercq, Nicole Legros
Publikováno v:
International Journal of Cancer. 78:760-765
Data from immunocytochemical assessment of estrogen receptor (ER) regulation in MCF-7 cells under estrogenic and anti-estrogenic stimulation were compared with those obtained by enzyme immunoassay (Abbott ER-EIA). Similar trends were observed, althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddef49e7e05a6325a230538381af8f8b
https://doi.org/10.1002/(sici)1097-0215(19981209)78:6<760::aid-ijc14>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19981209)78:6<760::aid-ijc14>3.0.co
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 41:545-552
It is well known that MCF-7 cells, when incubated with hydroxytamoxifen (OH-Tam) loose their capacity to bind [3H]estradiol. By using Western blotting and [3H]tamoxifen aziridine labeling of KCl extracts from these cells we found that this loss in bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1d0a9817b731f2ee8b317d54a963b2
https://doi.org/10.1016/0960-0760(92)90381-r
https://doi.org/10.1016/0960-0760(92)90381-r
Autor:
Guy Leclercq, F. Van Roy, Nicole Legros, Rudi Beyaert, Kris Vleminckx, N Devleeschouwer, Marcus Mareel, Walter Fiers, Carl Muquardt, M. Bracke
Publikováno v:
International Journal of Cancer. 46:522-532
Human mammary carcinoma cell lines (MCF-7) were analysed for their hormone sensitivity before and after transfection with a v-Ha-ras oncogene or with a neomycin-resistance gene followed by selection in vitro or in vivo. Our aim was to test how the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dace5358f17081582b5e47cb23f0a68a
https://doi.org/10.1002/ijc.2910460332
https://doi.org/10.1002/ijc.2910460332
Publikováno v:
Cancer chemotherapy and pharmacology. 41(4)
Linkage of specific residues onto steroidal estrogens through a long aliphatic side chain leads to "pure antiestrogens" devoid of residual estrogenic activity. Therefore, we assessed whether an increase in the length of the side chain of the tripheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c58f94e5564faf9e1eb2bccf5f85cf
https://pubmed.ncbi.nlm.nih.gov/9488604
https://pubmed.ncbi.nlm.nih.gov/9488604
Publikováno v:
Cancer chemotherapy and pharmacology. 39(4)
Treatment of estrogen receptor (ER)-positive mammary tumors with tamoxifen produces a dramatic accumulation of ER in the cell nucleus. We investigated whether this phenomenon might be related to the antitumor activity of the drug. Five tamoxifen deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f798257d70bebf3ada677be4cc15fbbf
https://pubmed.ncbi.nlm.nih.gov/9025781
https://pubmed.ncbi.nlm.nih.gov/9025781
Publikováno v:
Biochemical pharmacology. 42(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83ec0d70dac82b425414ae9a76753f4
https://pubmed.ncbi.nlm.nih.gov/1930303
https://pubmed.ncbi.nlm.nih.gov/1930303
Publikováno v:
European Journal of Cancer and Clinical Oncology. 26:164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aefb83554d1399e20ff0b8278228695
https://doi.org/10.1016/0277-5379(90)90361-v
https://doi.org/10.1016/0277-5379(90)90361-v
Publikováno v:
Acta Clinica Belgica. 44:73-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef31d9b8833c5facde12a43cf5a3ddf
https://doi.org/10.1080/17843286.1989.11717992
https://doi.org/10.1080/17843286.1989.11717992
Clinical significance of the quantitative assessment of estrogen receptors in advanced breast cancer
Autor:
Richard Sylvester, E. Ferrazzi, Robert Paridaens, Nicole Legros, Jean-Claude Heuson, Guy Leclercq
Publikováno v:
Cancer. 46:2889-2895
The predictive value of the (ER) estrogen receptor assay with regard to the response to hormonal treatment was analyzed in women with advanced breast carcinoma. The significance of clinical variables of putative prognostic value was also investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02fc9a4cf804fa2b80bd8221061bc252
https://doi.org/10.1002/1097-0142(19801215)46:12+<2889::aid-cncr2820461430>3.0.co
https://doi.org/10.1002/1097-0142(19801215)46:12+<2889::aid-cncr2820461430>3.0.co
Autor:
Richard Sylvester, Wolrad Mattheiem, Danilo Pratola, Jean-Claude Heuson, Pierre Mendes Da Costa, Guy Andry, Martine Andry-T'Hooft, Nicole Legros, Stefan Suciu, Guy Leclercq, Alain Verhest
Publikováno v:
European Journal of Cancer and Clinical Oncology. 25:319-329
After modified radical mastectomy, 490 primary breast cancer patients were followed for a median of 75 months. Bloom grade was measured in 340 patients and ER status in 341. Follow-up of these patients has yielded the following results: (a) The value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218196512f8565547965353200bd7b65
https://doi.org/10.1016/0277-5379(89)90025-4
https://doi.org/10.1016/0277-5379(89)90025-4