Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Nicole Lecot"'
1
Akademický článek
Acerola (Malpighia spp.) Waste: A Sustainable Approach to Nutraceutical, Pharmaceutical, and Energy Applications
Autor: José Roberto Vega-Baudrit, Melissa Camacho, Diego Batista-Menezes, Yendry Corrales-Ureña, Juan Miguel Zúñiga, Arturo Mora Chacón, Nicole Lecot, Luis Castillo Henríquez, Mary Lopretti
Publikováno v: Recycling, Vol 8, Iss 6, p 96 (2023)
This study reviews the many uses for waste generated from acerola (Malpighia spp.) production, a tropical fruit renowned for its nutrient-rich content. Traditionally considered an environmental burden, this waste is now gaining attention for its sust
Externí odkaz: https://doaj.org/article/50e91b70f4d74ef4ba2935f20f3e9d87
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2
Akademický článek
Biofilms Functionalized Based on Bioactives and Nanoparticles with Fungistatic and Bacteriostatic Properties for Food Packing Uses
Autor: Gabriela Lluberas, Diego Batista-Menezes, Juan Miguel Zuñiga-Umaña, Gabriela Montes de Oca-Vásquez, Nicole Lecot, José Roberto Vega-Baudrit, Mary Lopretti
Publikováno v: Biology and Life Sciences Forum, Vol 28, Iss 1, p 10 (2023)
The objective of this work was to formulate PVA films with the addition of modified phenols, chitosan, silver, or copper nanoparticles with fungistatic and bacteriostatic activity. The films were characterized by Fourier transform infrared spectrosco
Externí odkaz: https://doaj.org/article/8b12bb8bd719492cbb4e77c3c8010460
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3
Akademický článek
Development of fluorescent- and radio-traceable T1307-polymeric micelles as biomedical agents for cancer diagnosis: biodistribution on 4T1 tumor-bearing mice
Autor: Nicole Lecot, Gonzalo Rodríguez, Valentina Stancov, Marcelo Fernández, Mercedes González, Romina J. Glisoni, Pablo Cabral, Hugo Cerecetto
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract In recent years, nanocarriers have been studied as promising pharmaceutical tools for controlled drug-delivery, treatment-efficacy follow-up and disease imaging. Among them, X-shaped amphiphilic polymeric micelles (Tetronic®, poloxamines) d
Externí odkaz: https://doaj.org/article/afbe30a77c4f4d8790569ce988c78676
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4
Development and Evaluation of 2-Amino-7-Fluorophenazine 5,10-Dioxide Polymeric Micelles as Antitumoral Agents for 4T1 Breast Cancer
Autor: Nicole Lecot, Belén Dávila, Carina Sánchez, Marcelo Fernández, Mercedes González, Pablo Cabral, Hugo Cerecetto, Romina Glisoni
Publikováno v: Polymers; Volume 14; Issue 1; Pages: 71
Polymers
Polymers, Vol 14, Iss 71, p 71 (2022)
2-Amino-7-fluorophenazine 5,10-dioxide (FNZ) is a bioreducible prodrug, poorly soluble in water, with potential anticancer activity on hypoxic-tumors. This poor solubility limits its potential applications in clinic. Amphiphilic pristine polymeric mi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3338cf758e16ecac830ac9fa517a75a
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5
99mTc Stearyl 6-(benzylidenehydrazinyl) nicotinamide Liposomes as Tumor Permeability Evaluation Tracer
Autor: Williams Porcal, Mirel Cabrera, Pablo Cabral, Marcelo Fernández, Nicole Lecot, Juan Pablo Gambini
Publikováno v: AAPS PharmSciTech. 22
Nanomedicine is a highly demanded discipline. Liposomes have seen an increased attention due to their physicochemical properties that allow them to act as nanocarriers of drugs and also of radioisotopes that can be used to diagnose and treat cancer.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bd8620802b03c036024c356da0c6702
https://doi.org/10.1208/s12249-021-01984-1
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6
Akademický článek
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8
Selective Hypoxia-Cytotoxin 7-Fluoro-2-Aminophenazine 5,10-Dioxide: Toward Candidate-to-Drug Stage in the Drug-Development Pipeline
Autor: Hugo Cerecetto, Belén Dávila, Mercedes González, Nicole Lecot, Carina Sánchez, Marcelo Fernández, Romina Julieta Glisoni, Pablo Cabral
7-Fluoro-2-aminophenazine 5,10-dioxide, 1, has displayed in vitro bioreductive selective cytotoxicity, which could acts towards tumors containing hypoxic regions. In this work, we describe some preclinical studies of compound 1 confirming its in vivo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6019bd738a5b9eced1afd97d92fd2ff
Wiley Online Library
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10
2-Amino-7(8)-fluorophenazine N5,N10-dioxide: Scale-up and Toxicity Evaluation
Autor: Mirel Cabrera, Belén Dávila, Nicole Lecot, Joaquín Afonso, Pablo Cabral, Carina Sánchez, Mercedes González, Hugo Cerecetto
Publikováno v: Proceedings of 3rd International Electronic Conference on Medicinal Chemistry.
Breast cancer is a solid tumor characterized by a high level of hypoxic areas which are difficult to treat. The rate of this disease in women is elevated, mainly in developing countries since the diagnosis is made in the later stages of the disease.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4536ca1106719e6f0749494b239cdf7
https://doi.org/10.3390/ecmc-3-04672
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