Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nicole Laurencia Yuwono"'
Publikováno v:
eLife, Vol 10 (2021)
Research and clinical use of circulating cell-free DNA (cirDNA) is expanding rapidly; however, there remain large gaps in our understanding of the influence of lifestyle and biological factors on the amount of cirDNA present in blood. Here, we review
Externí odkaz:
https://doaj.org/article/b683edc190824bd7a4a9b0f135b52a02
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250561 (2021)
Assays measuring cell-free DNA (cfDNA) in blood have widespread potential in modern medicine. However, a comprehensive understanding of cfDNA dynamics in healthy individuals is required to assist in the design of assays that maximise the signal drive
Externí odkaz:
https://doaj.org/article/85f816acc7ca4dd5b125fc2fabe67a7a
Autor:
Bonnita Werner, Nicole Laurencia Yuwono, Claire Henry, Kate Gunther, Robert William Rapkins, Caroline Elizabeth Ford, Kristina Warton
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224338 (2019)
BACKGROUND:Methylation patterns in circulating cell-free DNA are potential biomarkers for cancer and other pathologies. Currently, bisulfite treatment underpins most DNA methylation analysis methods, however, it is known to fragment DNA. Circulating
Externí odkaz:
https://doaj.org/article/78a95ebe4e1b4471ada8cc5fbfb66294
Autor:
Nicole Laurencia Yuwono, Mollie Ailie Acheson Boyd, Claire Elizabeth Henry, Bonnita Werner, Caroline Elizabeth Ford, Kristina Warton
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 60:1287-1298
Objectives Circulating DNA (cirDNA) is generally purified from plasma that has been biobanked for variable lengths of time. In long-term experiments or clinical trials, the plasma can be stored frozen for up to several years. Therefore, it is crucial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e112371f3c94ff45e0291fdcd3df14
https://doi.org/10.1515/cclm-2021-1152
https://doi.org/10.1515/cclm-2021-1152
Autor:
Kristina Warton, Nicole Laurencia Yuwono, R. Rodgers, Anais Alonso, Caroline E. Ford, Sahar Houshdaran, Jason Abbott
Publikováno v:
Reproductive BioMedicine Online. 44:495-503
Research question: Do women with laparoscopically confirmed endometriosis have higher plasma concentrations of circulating cell-free DNA (cirDNA) than those without endometriosis? Design: This prospective study recruited women aged 18-45 years underg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0bbb64902ab44228997913309272416
https://doi.org/10.1016/j.rbmo.2021.11.006
https://doi.org/10.1016/j.rbmo.2021.11.006
Publikováno v:
Sports Medicine. 51:1799-1804
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6bb7346e8edbd89933b2a58896d227f
https://doi.org/10.1007/s40279-020-01405-6
https://doi.org/10.1007/s40279-020-01405-6
Autor:
Nicole Laurencia Yuwono, Pamela J. Provan, Sivatharsny Srirangan, Dongli Liu, Kristina Warton, Bonnita Werner, Jennifer Duggan, Caroline E. Ford, Catherine David, INOVATe Investigators, Vivek Arora, Anna deFazio, Yeh Chen Lee, Rhonda Farrell
Publikováno v:
Gynecologic oncology. 162(3)
Objective Malignant ascites is a common clinical feature of ovarian cancer and represents a readily accessible sample of tumour cells and tumour DNA. This study aimed to characterise the cell-free DNA (cfDNA) in ascites in terms of its size profile,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cdaf29f16dd3dea0d9457d33c5ed50
https://pubmed.ncbi.nlm.nih.gov/34454680
https://pubmed.ncbi.nlm.nih.gov/34454680
Publikováno v:
Cancer Genetics. :143-150
The utility of circulating DNA as a source of clinical biomarkers in blood is limited by its low concentration and small fragment size. Effective purification methods can maximize circulating DNA yield and contribute to the success of downstream prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795b29d351cad1c92bac4f3214f5317c
https://doi.org/10.1016/j.cancergen.2018.02.004
https://doi.org/10.1016/j.cancergen.2018.02.004
Autor:
Nicole Laurencia Yuwono, Kristina Warton, Caroline E. Ford, Mark J. McCabe, Alwin So, Mark J. Cowley
Publikováno v:
Molecular Diagnosis & Therapy. 21:563-570
Blood samples for studies of circulating DNA in disease are often collected in clinical settings where prompt processing of samples is not possible. In order to avoid problems associated with leukocyte lysis after prolonged blood storage, stabilised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3048ec21cf94f479db6afb89c6a4f9
https://doi.org/10.1007/s40291-017-0284-x
https://doi.org/10.1007/s40291-017-0284-x
Autor:
Caroline E. Ford, Robert W. Rapkins, Kate Gunther, Claire Henry, Kristina Warton, Nicole Laurencia Yuwono, Bonnita Werner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 10, p e0224338 (2019)
PLoS ONE, Vol 14, Iss 10, p e0224338 (2019)
Background Methylation patterns in circulating cell-free DNA are potential biomarkers for cancer and other pathologies. Currently, bisulfite treatment underpins most DNA methylation analysis methods, however, it is known to fragment DNA. Circulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9fb73400109b3befdc639e6d668ec14
https://pubmed.ncbi.nlm.nih.gov/31652288
https://pubmed.ncbi.nlm.nih.gov/31652288