Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicole L. Volk"'
Autor:
Tatiana Popovitchenko, Yongkyu Park, Nicholas F. Page, Xiaobing Luo, Zeljka Krsnik, Yuan Liu, Iva Salamon, Jessica D. Stephenson, Matthew L. Kraushar, Nicole L. Volk, Sejal M. Patel, H. R. Sagara Wijeratne, Diana Li, Kandarp S. Suthar, Aaron Wach, Miao Sun, Sebastian J. Arnold, Wado Akamatsu, Hideyuki Okano, Luc Paillard, Huaye Zhang, Steven Buyske, Ivica Kostovic, Silvia De Rubeis, Ronald P. Hart, Mladen-Roko Rasin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Translational regulation of isoforms in the developing nervous system is not well understood. Here, the authors report translational de-repression of RNA binding protein isoforms at their 5′UTRs in the neocortex and show the neurodevelopmental risk
Externí odkaz:
https://doaj.org/article/26ec0393d8414ff985171a47ea4a1728
Autor:
Nicole L. Volk, Ronald P. Hart, Xiaobing Luo, Yongkyu Park, Nicholas F. Page, Iva Salamon, Huaye Zhang, Yuan Liu, Sejal M. Patel, Sebastian J. Arnold, Mladen-Roko Rasin, Jessica D. Stephenson, H. R. Sagara Wijeratne, Kandarp S. Suthar, Silvia De Rubeis, Wado Akamatsu, Hideyuki Okano, Zeljka Krsnik, Miao Sun, Tatiana Popovitchenko, Diana Li, Aaron Wach, Ivica Kostović, Matthew L. Kraushar, Luc Paillard, Steven Buyske
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1674. ⟨10.1038/s41467-020-15412-8⟩
Nature Communications, 2020, 11 (1), pp.1674. ⟨10.1038/s41467-020-15412-8⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1674. ⟨10.1038/s41467-020-15412-8⟩
Nature Communications, 2020, 11 (1), pp.1674. ⟨10.1038/s41467-020-15412-8⟩
Neurodevelopment requires precise regulation of gene expression, including post-transcriptional regulatory events such as alternative splicing and mRNA translation. However, translational regulation of specific isoforms during neurodevelopment and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9feab16cc46e4785cf2ff5b0b3dcff59
http://link.springer.com/article/10.1038/s41467-020-15412-8
http://link.springer.com/article/10.1038/s41467-020-15412-8
Autor:
Huijuan Cui, Nicole L. Volk, Xiaobing Luo, Gabriella D'Arcangelo, Alfonso Roque, Ronald P. Hart, Ishan Khosla, Mladen-Roko Rasin, Geeta Palsule, Shawn Tucai, Iva Salamon, Wendy Liu, Megerditch Kiledjian, Xinfu Jiao, Valentina Dal Pozzo, Petronio Zalamea
Publikováno v:
Cereb Cortex
Homozygous mutations in the gene encoding the scavenger mRNA-decapping enzyme, DcpS, have been shown to underlie developmental delay and intellectual disability. Intellectual disability is associated with both abnormal neocortical development and mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4950a2c8b55912d949eddd052eea69b7
https://pubmed.ncbi.nlm.nih.gov/34467373
https://pubmed.ncbi.nlm.nih.gov/34467373
More than a passive effector of gene expression, mRNA translation (protein synthesis) by the ribosome is a rapidly tunable and dynamic molecular mechanism. Neurodevelopmental disorders are associated with abnormalities in mRNA translation, protein sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc8750cecff07d4ff4c4a8f03a241b0
https://europepmc.org/articles/PMC5124555/
https://europepmc.org/articles/PMC5124555/
