Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nicole L. Valvano"'
Autor:
Jeffrey A. Stafford, Alan B Strickland, D. Rose, Paul L. Domanico, Michael A. Leesnitzer, David J. Cowan, Rayomand J. Unwalla, Stephen A. Stimpson, Paul L. Feldman, Nicole L. Valvano, E Sloan Brawley, Margrith W. Verghese
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1977-1982
Structure-activity relationships within a series of 1,3,4-trisubstituted pyrrolidines, novel and selective inhibitors of cAMP-specific phosphodiesterase (PDE IV), are discussed.
Autor:
Jeffrey A. Stafford, Rayomand J. Unwalla, Frank J. Schoenen, Paul L. Feldman, Brian Edward Marron, Paul L. Domanico, Nicole L. Valvano, E Sloan Brawley, D. Rose, Michael A. Leesnitzer, Robert W. Dougherty
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1855-1860
Structure-activity relationships involving the aromatic ring of the selective PDE IV inhibitor, rolipram (1), are discussed.