Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nicole L. Prokopishyn"'
Autor:
Ju Huang, Aneal Khan, Bryan C. Au, Dwayne L. Barber, Lucía López-Vásquez, Nicole L. Prokopishyn, Michel Boutin, Michael Rothe, Jack W. Rip, Mona Abaoui, Murtaza S. Nagree, Shaalee Dworski, Axel Schambach, Armand Keating, Michael L. West, John Klassen, Patricia V. Turner, Sandra Sirrs, C. Anthony Rupar, Christiane Auray-Blais, Ronan Foley, Jeffrey A. Medin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 241-258 (2017)
Fabry disease is a rare lysosomal storage disorder (LSD). We designed multiple recombinant lentivirus vectors (LVs) and tested their ability to engineer expression of human α-galactosidase A (α-gal A) in transduced Fabry patient CD34+ hematopoietic
Externí odkaz:
https://doaj.org/article/72a85a8769b142ad9ecbd535f945b6c9
Predictive factors for successful peripheral blood stem cell mobilization and collection in children
Publikováno v:
Journal of Clinical Apheresis. 34:598-606
Factors affecting the success of peripheral blood stem cell collection (SCC) in children are not well characterized. We reviewed 218 stem cell collections among 199 pediatric donors, of which 35 were from healthy sibling donors and 164 were for autol
Autor:
Poonam Dharmani-Khan, Joanne Luider, Faisal Khan, Andrew Daly, Jan Storek, Nicole L. Prokopishyn, Shahbal B. Kangarloo, Rosy Dabas, Kareem Jamani
Publikováno v:
Biology of Blood and Marrow Transplantation. 25:639-647
Antithymocyte globulin (ATG) levels and clearance vary significantly among patients receiving the same weight-based dose of ATG. To date, ATG area under the curve (AUC), its determinants, and its impact on clinical outcomes have been examined in pedi
Autor:
Jan Storek, Victor H Jimenez-Zepeda, Faisal Khan, Andrew Daly, Poonam Dharmani-Khan, Samar Ousia, Kareem Jamani, Peter Duggan, Tyler Williamson, Nicole L. Prokopishyn, Amit Kalra, James A. Russell
Publikováno v:
Clinical transplantationREFERENCES. 34(9)
Optimal conditioning and graft-vs-host disease (GVHD) prophylaxis for hematopoietic cell transplantation (HCT) are unknown. Here, we report on outcomes after low toxicity, myeloablative conditioning consisting of fludarabine, busulfan, and 4 Gy total
Autor:
Mona Abaoui, Axel Schambach, Michael Rothe, Aneal Khan, Jeffrey A. Medin, John S. Klassen, Ju Huang, Jack W. Rip, Michael West, Armand Keating, Lucia Lopez-Vasquez, Ronan Foley, Murtaza S. Nagree, Sandra Sirrs, Christiane Auray-Blais, Dwayne L. Barber, Michel Boutin, Bryan Au, Nicole L. Prokopishyn, Patricia V. Turner, Shaalee Dworski, C. Anthony Rupar
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 241-258 (2017)
Fabry disease is a rare lysosomal storage disorder (LSD). We designed multiple recombinant lentivirus vectors (LVs) and tested their ability to engineer expression of human α-galactosidase A (α-gal A) in transduced Fabry patient CD34+ hematopoietic
Autor:
Nicole L. Prokopishyn, Gregory M.T. Guilcher, Tony H. Truong, R Moorjani, Deborah Dewey, Victor Lewis
Publikováno v:
Bone Marrow Transplantation. 51:680-686
Adverse reactions (ARs) during the infusion of cellular therapy products (CTPs) are common in patients undergoing hematopoietic stem cell transplantation (HSCT). We retrospectively studied pediatric patients undergoing autologous and allogeneic HSCT
Autor:
Jan Storek, Cameron Griffiths, Andrew Daly, Muhammad Amlish Munir, Nicole L. Prokopishyn, Yiping Liu, Douglas A. Stewart, Poonam Dharmani-Khan, Faisal Khan, Sumit Chawla, James A. Russell
Publikováno v:
Biology of Blood and Marrow Transplantation. 20(8):1156-1162
Rabbit antithymocyte globulin (ATG) is administered during transplant conditioning to decrease the risk of both acute graft-versus-host disease (aGVHD) and chronic graft-versus-host disease (cGVHD). Here we evaluated the relationship between the seru
Autor:
Doug Strother, Nicole L. Prokopishyn, Lucie Lafay-Cousin, Tony H. Truong, George Michaiel, Henry Luu, Greg Guilcher, Victor Lewis
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 45:S9-S9
BACKGROUND: The use of high-dose chemotherapy (HDC) and autologous hematopoietic stem cell transplant (HSCT) has been used in certain pediatric patients with brain tumours to delay/spare radiotherapy. We aimed to study factors predicting a successful
Autor:
Daniele Moratto, Qing Yan, Fabio Candotti, R. Michael Blaese, Linda M. Muul, Kumar Felix, Jacquelin H. Bui, Brian R. Davis, Nicole L. Prokopishyn
Publikováno v:
Clinical Immunology. 135:72-83
The reasons underlying the occurrence of multiple revertant genotypes in Wiskott-Aldrich syndrome (WAS) patients remain unclear. We have identified more than 30 revertant genotypes in a C995T WAS patient having 10-15% revertant, WAS protein (WASp)-ex
Autor:
Fabio Candotti, Linda M. Muul, Nicole L. Prokopishyn, Daniele Moratto, Michael DiCola, Brian R. Davis, Jonathan B. Rosenberg, R. Michael Blaese
Publikováno v:
Blood. 111:5064-5067
Spontaneous somatic reversions of inherited mutations are poorly understood phenomena that are thought to occur uncommonly in a variety of genetic disorders. When molecularly characterized, revertant cells have rarely exhibited more than one revertan