Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicole L. Kushner"'
Autor:
Lu Huang, Nicole L. Kushner, Monique E. Theriault, Davide Pisu, Shumin Tan, Case W. McNamara, H. Mike Petrassi, David G. Russell, Amanda C. Brown
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Mycobacterium tuberculosis (Mtb) continues to be a threat to Global Public Health, and its control will require an array of therapeutic strategies. It has been appreciated that high-throughput screens using cell-based assays to identify compounds tar
Externí odkaz:
https://doaj.org/article/b7e17853d3d9438abea37fe30b8b5caa
Autor:
Liana Tsenova, Pooja Singh, Gilla Kaplan, Afsal Kolloli, Nicole L. Kushner, Selvakumar Subbian, Dorothy Fallows, Paul O'Brien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f170f3eaa902f9ece7795402b5cc54d1
https://doi.org/10.1002/eji.201948448/v2/response1
https://doi.org/10.1002/eji.201948448/v2/response1
Autor:
Dorothy Fallows, Selvakumar Subbian, Paul O'Brien, Pooja Singh, Afsal Kolloli, Liana Tsenova, Nicole L. Kushner, Gilla Kaplan
Publikováno v:
European journal of immunologyReferences. 50(6)
Host protective immunity against pathogenic Mycobacterium tuberculosis (Mtb) infection is variable and poorly understood. Both prior Mtb infection and BCG vaccination have been reported to confer some protection against subsequent infection and/or di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32de032887e10ea3431d18f4db7d2737
https://pubmed.ncbi.nlm.nih.gov/32130727
https://pubmed.ncbi.nlm.nih.gov/32130727
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2042
High-throughput drug screening (HTS) is a powerful tool that can be used rapidly to identify new potential bacterial inhibitors and/or compounds which enhance host cell control of pathogens, which can then go on to be developed as novel therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd05fb6688372083d95550eb1036722a
https://pubmed.ncbi.nlm.nih.gov/31385282
https://pubmed.ncbi.nlm.nih.gov/31385282
Autor:
Amanda C. Brown, Nicole L. Kushner
Publikováno v:
Chlamydia trachomatis ISBN: 9781493996933
High-throughput drug screening (HTS) is a powerful tool that can be used rapidly to identify new potential bacterial inhibitors and/or compounds which enhance host cell control of pathogens, which can then go on to be developed as novel therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8699ce6b34dc2059a6865a4fad58ee3
https://doi.org/10.1007/978-1-4939-9694-0_18
https://doi.org/10.1007/978-1-4939-9694-0_18
Autor:
Dorothy Fallows, Gilla Kaplan, Paul O'Brien, Liana Tsenova, Sven D.C. Parsons, Blas Peixoto, Selvakumar Subbian, Nicole L. Kushner, Guibin Yang
Publikováno v:
The American Journal of Pathology. 181(5):1711-1724
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is an exquisitely adapted human pathogen capable of surviving for decades in the lungs of immune-competent individuals in the absence of disease. The World Health Organizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2177e37e5c0cb9cba468d6f65c4aa974
Autor:
W. Brad Wan, Mark N. Prichard, Shannon Daily, Caroll B. Hartline, Karl Y. Hostetler, James R. Beadle, Nicole L. Kushner, Earl R. Kern, Emma A. Harden, Stephanie L. Williams-Aziz
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:3724-3733
Cidofovir (CDV) is an effective therapy for certain human cytomegalovirus (HCMV) infections in immunocompromised patients that are resistant to other antiviral drugs, but the compound is not active orally. To improve oral bioavailability, a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ebe5e9be8f8efa7f094e455472fed6
https://doi.org/10.1128/aac.49.9.3724-3733.2005
https://doi.org/10.1128/aac.49.9.3724-3733.2005
Autor:
Earl R. Kern, Karen K. Biron, Stephanie L. Williams, Emma A. Harden, Leroy B. Townsend, Deborah J. Bidanset, Mark R. Underwood, John C. Drach, Nicole L. Kushner, Caroll B. Hartline
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:2186-2192
Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2), varicella-zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), human herpesvirus 6 (HHV-6), and human herpesvirus 8 (HHV-8) are responsible for a number of clinical manifestations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c9e586affcd539663967b57a79ea83
https://doi.org/10.1128/aac.47.7.2186-2192.2003
https://doi.org/10.1128/aac.47.7.2186-2192.2003
Publikováno v:
Antiviral Research. 58:149-157
Epstein–Barr virus (EBV), human herpesvirus type 6 (HHV-6), and human herpesvirus type 8 (HHV-8) comprise a group of lymphotropic herpesviruses which are responsible for a wide range of diseases, including lymphoproliferative disorders and tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738e95b3fa13e82de60af29c3581a780
https://doi.org/10.1016/s0166-3542(02)00210-3
https://doi.org/10.1016/s0166-3542(02)00210-3
Autor:
Joel S. Bader, Nirmalya Bandyopadhyay, Liana Tsenova, Dorothy Fallows, Petros C. Karakousis, Blas Peixoto, Patricia Soteropoulos, Gilla Kaplan, Nicole L. Kushner, Viraj V Khetani, Paul O'Brien, Selvakumar Subbian
Publikováno v:
Cell Communication and Signaling : CCS
BackgroundPulmonary infection of humans byMycobacterium tuberculosis(Mtb), the causative agent of tuberculosis (TB), results in active disease in 5-10% of individuals, while asymptomatic latent Mtb infection (LTBI) is established in the remainder. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abfa2573bcf386981292fcf10a32f7d
https://doi.org/10.1186/1478-811x-11-60
https://doi.org/10.1186/1478-811x-11-60