Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nicole L. Inniss"'
Autor:
Emma H. Kelley, George Minasov, Katherine Konczak, Ludmilla Shuvalova, Joseph S. Brunzelle, Shantanu Shukla, Megan Beulke, Teerana Thabthimthong, Kenneth W. Olsen, Nicole L. Inniss, Karla J. F. Satchell, Daniel P. Becker
Publikováno v:
ACS Omega, Vol 9, Iss 3, Pp 3905-3915 (2024)
Externí odkaz:
https://doaj.org/article/98462c203ea04897ab04bda68a113bb3
Autor:
Nicole L. Inniss, Margarita Rzhetskaya, Ted Ling-Hu, Ramon Lorenzo-Redondo, Kelly E. Bachta, Karla J.F. Satchell, Judd F. Hultquist
Publikováno v:
SLAS Discovery, Vol 29, Iss 3, Pp 100145- (2024)
SARS-CoV-2 nsp13 helicase is an essential enzyme for viral replication and a promising target for antiviral drug development. This study compares the double-stranded RNA (dsRNA) unwinding activity of nsp13 and the Omicron nsp13R392C variant, which is
Externí odkaz:
https://doaj.org/article/eb32c9ea90b64b2d853170267438612d
Autor:
Jacob P. Vandervaart, Nicole L. Inniss, Ted Ling-Hu, George Minasov, Grant Wiersum, Monica Rosas-Lemus, Ludmilla Shuvalova, Chad J. Achenbach, Judd F. Hultquist, Karla J. F. Satchell, Kelly E. R. Bachta
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The SARS-CoV-2 nucleocapsid (N) protein is highly immunogenic, and anti-N antibodies are commonly used as markers for prior infection. While several studies have examined or predicted the antigenic regions of N, these have lacked consensus a
Externí odkaz:
https://doaj.org/article/db4801eec0fa4569ab48e42557529341
Autor:
Nicole L. Inniss, Donald A. Morrison
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
The alternative streptococcal σ-factor and master competence regulator, σX, stimulates transcription from competence promoters, in vitro. As the only known alternative σ-factor in streptococci, σX expression is tightly controlled in each species
Externí odkaz:
https://doaj.org/article/b9cf3a5fffa04d71abf757b4286312e6
Autor:
George Minasov, Nicole L. Inniss, Ludmilla Shuvalova, Wayne F. Anderson, Karla J. F. Satchell
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 78:371-377
The infectious disease human monkeypox is spreading rapidly in 2022, causing a global health crisis. The genomics of Monkeypox virus (MPXV) have been extensively analyzed and reported, although little is known about the virus-encoded proteome. In par
Autor:
Nicole L. Inniss, Travis J. Kochan, George Minasov, Zdzislaw Wawrzak, Changsoo Chang, Kemin Tan, Ludmilla Shuvalova, Olga Kiryukhina, Sergii Pshenychnyi, Ruiying Wu, Ivegeniia Dubrovska, Gyorgy Babnigg, Michael Endres, Wayne F. Anderson, Alan R. Hauser, Andrzej Joachimiak, Karla J. F. Satchell
Publikováno v:
Microbiology Resource Announcements. 12
Klebsiella pneumoniae is a leading cause of antibiotic-resistant-associated deaths in the world. Here, we report the deposition of 14 structures of enzymes from both the core and accessory genomes of sequence type 23 (ST23) K1 hypervirulent K. pneumo
Autor:
George Minasov, Nicole L. Inniss, Ludmilla Shuvalova, Wayne F. Anderson, Karla J. F. Satchell
The infectious disease human monkeypox is spreading rapidly in 2022 causing a global health crisis. The genomics of the monkeypox virus (MPXV) have been extensively analyzed and reported, although little is known about the virus-encoded proteome. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c0e123293a6be555e833aa65c5f6c27
https://doi.org/10.1101/2022.08.07.503103
https://doi.org/10.1101/2022.08.07.503103
Autor:
Nicole L. Inniss, George Minasov, Courtney M. Daczkowski, Andrew D. Mesecar, Karla J. F. Satchell, Paul Hoover, Joseph S. Brunzelle, Monica Rosas-Lemus, Ludmilla Shuvalova
Publikováno v:
Science Signaling
Efficient RNA capping by the SARS-CoV-2 methyltransferase requires metal ions and a unique four-residue insert.
Uniquely coronavirus Virally encoded 2′-O-methyltransferases catalyze the last step in the capping of viral RNAs, which protects th
Uniquely coronavirus Virally encoded 2′-O-methyltransferases catalyze the last step in the capping of viral RNAs, which protects th
Publikováno v:
Journal of Biological Chemistry. 294:11101-11118
Natural genetic transformation via horizontal gene transfer enables rapid adaptation to dynamic environments and contributes to both antibiotic resistance and vaccine evasion among bacterial populations. In Streptococcus pneumoniae (pneumococcus), tr
Autor:
George Minasov, Monica Rosas-Lemus, Karla J. F. Satchell, Courtney M. Daczkowski, Paul Hoover, Ludmilla Shuvalova, Joseph S. Brunzelle, Andrew D. Mesecar, Nicole L. Inniss
Capping viral messenger RNAs is essential for efficient translation and prevents their detection by host innate immune responses. For SARS-CoV-2, RNA capping includes 2′-O-methylation of the first ribonucleotide by methyltransferase nsp16 in comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb28209c55d6c1925e37ca15ed6ab39
https://doi.org/10.1101/2021.01.31.429023
https://doi.org/10.1101/2021.01.31.429023