Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicole L. Held"'
Autor:
Shengzhang Dong, Velmurugan Balaraman, Asher M Kantor, Jingyi Lin, DeAna G Grant, Nicole L Held, Alexander W E Franz
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005976 (2017)
In the mosquito, the midgut epithelium is the initial tissue to become infected with an arthropod-borne virus (arbovirus) that has been acquired from a vertebrate host along with a viremic bloodmeal. Following its replication in midgut epithelial cel
Externí odkaz:
https://doaj.org/article/7d6b7ba65ec546e99535d071d00cc5c4
Autor:
Shengzhang Dong, Jingyi Lin, Nicole L Held, Rollie J Clem, A Lorena Passarelli, Alexander W E Franz
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122353 (2015)
In vivo targeted gene disruption is a powerful tool to study gene function. Thus far, two tools for genome editing in Aedes aegypti have been applied, zinc-finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN). As a promi
Externí odkaz:
https://doaj.org/article/11ca0e83c774408baafbd344dbcc5350
Autor:
Hinsby Cadillo-Quiroz, Xavier Didelot, Nicole L Held, Alfa Herrera, Aaron Darling, Michael L Reno, David J Krause, Rachel J Whitaker
Publikováno v:
PLoS Biology, Vol 10, Iss 2, p e1001265 (2012)
Despite a growing appreciation of their vast diversity in nature, mechanisms of speciation are poorly understood in Bacteria and Archaea. Here we use high-throughput genome sequencing to identify ongoing speciation in the thermoacidophilic Archaeon S
Externí odkaz:
https://doaj.org/article/c4029cd76eb944d6beba2e2efbf9089f
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Predator-prey models for virus-host interactions predict that viruses will cause oscillations of microbial host densities due to an arms race between resistance and virulence. A new form of microbial resistance, CRISPRs (clustered regularly interspac
Externí odkaz:
https://doaj.org/article/9b4016dc9de54bc59f3573350087188a
Autor:
Alexander W. E. Franz, Asher M. Kantor, Shengzhang Dong, Egide Ishimwe, A. L. Passarelli, Rollie J. Clem, Nicole L. Held
Publikováno v:
Insect Molecular Biology. 26:113-126
Aedes aegypti is a major vector for arboviruses such as dengue, chikungunya and Zika viruses. During acquisition of a viremic bloodmeal, an arbovirus infects mosquito midgut cells before disseminating to secondary tissues, including the salivary glan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8391231dafcbfb3c95e46ebbf3447d
https://doi.org/10.1111/imb.12275
https://doi.org/10.1111/imb.12275
Autor:
De Ana G. Grant, Jingyi Lin, Velmurugan Balaraman, Nicole L. Held, Shengzhang Dong, Alexander W. E. Franz, Asher M. Kantor
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005976 (2017)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
In the mosquito, the midgut epithelium is the initial tissue to become infected with an arthropod-borne virus (arbovirus) that has been acquired from a vertebrate host along with a viremic bloodmeal. Following its replication in midgut epithelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb698e5453acaeab4ccc4a10a5c13c8
http://europepmc.org/articles/PMC5636170?pdf=render
http://europepmc.org/articles/PMC5636170?pdf=render
Publikováno v:
Evolution; International Journal of Organic Evolution
The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) system is a recently discovered type of adaptive immune defense in bacteria and archaea that functions via directed incorporation of viral and plasmid DNA into host genomes. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d8de93fbebf6b3643d7a52511309ca
http://europepmc.org/articles/PMC3437473
http://europepmc.org/articles/PMC3437473
Autor:
Nicole L. Held, Christopher N. Bowman, Danielle S. W. Benoit, Amber E. Rydholm, Kristi S. Anseth
Publikováno v:
Journal of Biomedical Materials Research Part A. :23-30
Thiol-acrylate photopolymers often contain pendant, unreacted thiol groups even following complete reaction of the acrylate functional groups. The results presented herein demonstrate a high throughput method for quantifying pendant thiol group conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0591b1c59be0685e98b76ce7799eeb3
https://doi.org/10.1002/jbm.a.31526
https://doi.org/10.1002/jbm.a.31526
Autor:
Alexander W. E. Franz, Shengzhang Dong, A. Lorena Passarelli, Nicole L. Held, Rollie J. Clem, Jingyi Lin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0122353 (2015)
PLoS ONE, Vol 10, Iss 3, p e0122353 (2015)
In vivo targeted gene disruption is a powerful tool to study gene function. Thus far, two tools for genome editing in Aedes aegypti have been applied, zinc-finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN). As a promi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098198d18aa92d79a710a13333427bcc
https://pubmed.ncbi.nlm.nih.gov/25815482
https://pubmed.ncbi.nlm.nih.gov/25815482
Publikováno v:
Environmental Microbiology.
Summary Virus–host interactions are a key factor shaping population dynamics of microbial species. The CRISPR-Cas adaptive immune system confers sequence-specific immunity to viral infection and has the potential to dramatically shape coevolutionar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2f27c1badf62689afe32c975c6a3d88
https://doi.org/10.1111/1462-2920.12146
https://doi.org/10.1111/1462-2920.12146