Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nicole L. Harzdorf"'
Publikováno v:
Organic Letters. 12:1304-1307
Separate short and modular syntheses of the isomeric natural products caryolanemagnolol and clovanemagnolol have been achieved starting from commercially available (-)-caryophyllene. The postulated biosynthetic pathways guided the syntheses of the ne
Autor:
Danby Kang, Christine E. Schmidt, Nicole L. Harzdorf, Zin Z. Khaing, Travis W. Shaw, Andrew M. Camelio, Xu Cheng, Dionicio Siegel
Publikováno v:
Organicbiomolecular chemistry. 10(2)
The use of small molecules that can promote neuronal growth represents a promising approach to regenerative science. Along these lines we have developed separate short or modular syntheses of the natural products caryolanemagnolol and clovanemagnolol
Autor:
Scott D. Larsen, Susan M. Wade, Andrew J. Kocab, Nicole L. Harzdorf, Jessica L. Bell, H. D. Hollis Showalter, Richard R. Neubig, Jenny G. Ryu, Chris R. Evelyn
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(2)
We recently identified bis(amide) CCG-1423 (1) as a novel inhibitor of RhoA/C-mediated gene transcription that is capable of inhibiting invasion of PC-3 prostate cancer cells in a Matrigel model of metastasis. An initial structure-activity relationsh