Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Nicole L Nichols"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionIntrapleural injections of cholera toxin B conjugated to saporin (CTB-SAP) result in selective respiratory (e.g., phrenic) motor neuron death and mimics aspects of motor neuron disease [(e.g., amyotrophic lateral sclerosis (ALS) and spina
Externí odkaz:
https://doaj.org/article/5b553c859ea948338944406cf083483b
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88161 (2014)
NK1 receptors, which bind substance P, are present in the majority of brainstem regions that contain CO2/H(+)-sensitive neurons that play a role in central chemosensitivity. However, the effect of substance P on the chemosensitive response of neurons
Externí odkaz:
https://doaj.org/article/6e84fb8c1a564021bfa25ff996d3dc8d
Autor:
Amy N. Keilholz, Ishan Pathak, Catherine L. Smith, Kate L. Osman, Lauren Smith, Grace Oti, Mojgan Golzy, Lixin Ma, Teresa E. Lever, Nicole L. Nichols
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionTongue weakness and atrophy can lead to deficits in the vital functions of breathing and swallowing in patients with motor neuron diseases (MNDs; e.g., amyotrophic lateral sclerosis (ALS) and pseudobulbar palsy), often resulting in aspira
Externí odkaz:
https://doaj.org/article/bd704596fda541c590c6727ea41c2f81
Autor:
Jose Marquez, Zayd Al Rawi, Elizabeth C. Bryda, Daniel J. Davis, Mona O. Garro-Kacher, Caley E. Smith, Christian L. Lorson, Catherine L Smith, Nicole L. Nichols, Amy N Keilholz, Jiude Mao, Eric Villalón, Sara M. Ricardez Hernandez, Toni I. Morcos, Monique A. Lorson
Publikováno v:
Hum Mol Genet
Spinal muscular atrophy with respiratory distress type I (SMARD1) is a neurodegenerative disease defined by respiratory distress, muscle atrophy and sensory and autonomic nervous system defects. SMARD1 is a result of mutations within the IGHMBP2 gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e310a1294d2dab45144a52ff823d0f
https://doi.org/10.1093/hmg/ddab317
https://doi.org/10.1093/hmg/ddab317
Autor:
Nguyen P. Nguyen, Stephanie Lopez, Catherine L. Smith, Teresa E. Lever, Nicole L. Nichols, Filiz Bunyak
Publikováno v:
2022 IEEE Applied Imagery Pattern Recognition Workshop (AIPR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7c5a07591b7ee0b7d172c5c76f31526
https://doi.org/10.1109/aipr57179.2022.10092238
https://doi.org/10.1109/aipr57179.2022.10092238
Autor:
Nicole L. Nichols, Gordon S. Mitchell
Publikováno v:
J Neurophysiol
Moderate acute intermittent hypoxia (mAIH; 35–55 mmHg Pa(O(2))) elicits phrenic long-term facilitation (pLTF) by a mechanism that requires activation of G(q) protein-coupled serotonin type 2 receptors, MEK/ERK MAP kinase, and NADPH oxidase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea22dff7e4d3f2ae9807ab75cfb0cf31
https://doi.org/10.1152/jn.00691.2020
https://doi.org/10.1152/jn.00691.2020
Autor:
Erika R. Murphy, Rebecca Thompson, Kate L. Osman, Chandler Haxton, Margaret Brothers, Li Lee, Kristen Warncke, Catherine L. Smith, Amy N. Keilholz, Ali Hamad, Mojgan Golzy, Filiz Bunyak, Lixin Ma, Nicole L. Nichols, Teresa E. Lever
Publikováno v:
Frontiers in Neuroscience. 16
The tongue plays a crucial role in the swallowing process, and impairment can lead to dysphagia, particularly in motor neuron diseases (MNDs) resulting in hypoglossal-tongue axis degeneration (e.g., amyotrophic lateral sclerosis and progressive bulba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c141b4d6a0844331fa8537b81bb98986
https://doi.org/10.3389/fnins.2022.869592
https://doi.org/10.3389/fnins.2022.869592
Autor:
Nicole L. Nichols, Erika R. Murphy, Kate Osman, Catherine L. Smith, Rebecca Thompson, Ashley Kloepper, Chandler Haxton, Kristen Warncke, Li Lee, Lixin Ma, Teresa E. Lever
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a00bdc8bd1bd1b57222bc5f1d77d8b4b
https://doi.org/10.1096/fasebj.2022.36.s1.r4029
https://doi.org/10.1096/fasebj.2022.36.s1.r4029
Autor:
Marissa Mueller, Rebecca Thompson, Kate L. Osman, Ellyn Andel, Chandler A. DeJonge, Sophia Kington, Zola Stephenson, Ali Hamad, Filiz Bunyak, Nicole L. Nichols, Teresa E. Lever
Publikováno v:
Dysphagia
Current treatments for dysphagia in ALS do not target the underlying tongue weakness and denervation atrophy that is prevalent in spinal and bulbar ALS cases. To address this clinical gap, we studied the low copy number SOD1-G93A (LCN-SOD1) mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80bd533ee78675c9409f917cb65ce53
https://europepmc.org/articles/PMC9568622/
https://europepmc.org/articles/PMC9568622/
Publikováno v:
Muscle Nerve
Introduction We recently developed an inducible model of dysphagia using intralingual injection of cholera toxin B conjugated to saporin (CTB-SAP) to cause death of hypoglossal neurons. In this study we aimed to evaluate tongue morphology and ultrast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0485228036016f6e6848c1b6df641189
https://doi.org/10.1002/mus.27131
https://doi.org/10.1002/mus.27131