Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Nicole L Lohr"'
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0257896 (2021)
IntroductionPeripheral artery disease (PAD) is a highly morbid condition in which impaired blood flow to the limbs leads to pain and tissue loss. Previously we identified 670 nm electromagnetic energy (R/NIR) to increase nitric oxide levels in cells
Externí odkaz:
https://doaj.org/article/9e7728b8a5b842d696c2644ca42a9bec
Autor:
Dorothee Weihrauch, John G Krolikowski, Deron W Jones, Tahniyath Zaman, Omoshalewa Bamkole, Janine Struve, Savin Pillai, Paul S Pagel, Nicole L Lohr, Kirkwood A Pritchard
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0151999 (2016)
Interferon regulatory factor 5 (IRF5) has been called a "master switch" for its ability to determine whether cells mount proinflammatory or anti-inflammatory responses. Accordingly, IRF5 should be an attractive target for therapeutic drug development
Externí odkaz:
https://doaj.org/article/c9747cfa4b5b42a0ae1f8cd9bcc8f2e0
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 668 (2024)
Red light (670 nm) energy controls vasodilation via the formation of a transferable endothelium-derived nitric oxide (NO)-precursor-containing substance, its intracellular traffic, and exocytosis. Here we investigated the underlying mechanistic effec
Externí odkaz:
https://doaj.org/article/81fd239b3c1f45859f3df1b2cee72a7b
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Nitric oxide dependent vasodilation is an effective mechanism for restoring blood flow to ischemic tissues. Previously, we established an ex vivo murine model whereby red light (670 nm) facilitates vasodilation via an endothelium derived vasoactive s
Externí odkaz:
https://doaj.org/article/85c6377ef03545bfbf25867603828995
Autor:
Jakara Griffin, John G. Krolikowski, Kenisha Kounga, Janine Struve, Agnes Keszler, Brian Lindemer, Michelle Bordas, Grant Broeckel, Nicole L. Lohr, Dorothee Weihrauch
Publikováno v:
Journal of Pregnancy, Vol 2022 (2022)
Preeclampsia is a serious pregnancy disorder which in extreme cases may lead to maternal and fetal injury or death. Preexisting conditions which increase oxidative stress, e.g., hypertension and diabetes, increase the mother’s risk to develop preec
Externí odkaz:
https://doaj.org/article/54e6262765654285a54734a0879b2177
Publikováno v:
Circulation. 145
Introduction: Women with a history of preeclampsia (PreE) or preterm (PreT) birth are at elevated risk of future hypertension, ischemic heart disease, and stroke. Mechanisms for this increased risk are unknown. Flow-mediated dilation of the brachial
Publikováno v:
Journal of the American College of Cardiology. 81:2716
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Preeclampsia is a leading cause of maternal morbidity and mortality worldwide, complicating 2-8% of pregnancies. The etiology of PE is poorly understood, the role of placental extracellular matrix (pECM) in PE is understudied. Extravillous trophoblas
Publikováno v:
Redox Biology, Vol 20, Iss, Pp 13-18 (2019)
There is significant therapeutic advantage of nitric oxide synthase (NOS) independent nitric oxide (NO) production in maladies where endothelium, and thereby NOS, is dysfunctional. Electromagnetic radiation in the red and near infrared region has bee
Autor:
Shannon, Tai, Divyanshu, Mohananey, Claire, Griffiths, Bradley, Johnson, Jalaj, Garg, Timothy J, Ridolfi, Nicole L, Lohr, Sakti, Chakrabarti, Sherry-Ann, Brown
Publikováno v:
American Heart Journal Plus: Cardiology Research and Practice. 17:100147
A 48-year-old female with metastatic colon adenocarcinoma and history of pre-existing coronary vasospasm with ventricular tachycardia (VT) successfully tolerated