Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nicole L Diggins"'
Autor:
Samuel Medica, Lindsey B Crawford, Michael Denton, Chan-Ki Min, Taylor A Jones, Timothy Alexander, Christopher J Parkins, Nicole L Diggins, Gabriel J Streblow, Adam T Mayo, Craig N Kreklywich, Patricia Smith, Sophia Jeng, Shannon McWeeney, Meaghan H Hancock, Andrew Yurochko, Michael S Cohen, Patrizia Caposio, Daniel N Streblow
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011682 (2023)
Human cytomegalovirus (HCMV) encodes multiple putative G protein-coupled receptors (GPCRs). US28 functions as a viral chemokine receptor and is expressed during both latent and lytic phases of virus infection. US28 actively promotes cellular migratio
Externí odkaz:
https://doaj.org/article/c4deb3fdeb3d4b18942e4ecdab4602f4
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Human cytomegalovirus (HCMV) is a highly prevalent beta-herpesvirus and a significant cause of morbidity and mortality following hematopoietic and solid organ transplant, as well as the leading viral cause of congenital abnormalities. A key
Externí odkaz:
https://doaj.org/article/d1611c7c034140f68ba91dbe8d45937d
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Each herpesvirus family establishes latency in a unique cell type. Since herpesviruses genomes are maintained as episomes, the viruses need to devise mechanisms to retain the latent genome during cell division.
Externí odkaz:
https://doaj.org/article/7beab12f4ad247e89b494036072c8109
Publikováno v:
Pathogens, Vol 10, Iss 2, p 200 (2021)
Human cytomegalovirus (HCMV) encodes 22 mature microRNAs (miRNAs), which regulate a myriad of cellular processes, including vesicular trafficking, cell cycle progression, apoptosis, and immune evasion, as well as viral gene expression. Recent evidenc
Externí odkaz:
https://doaj.org/article/060b0c51ba27490082881f372da7d040
Autor:
Nicole L. Diggins, Meaghan H. Hancock
Publikováno v:
Seminars in celldevelopmental biology.
Viruses have evolved a multitude of mechanisms to combat barriers to productive infection in the host cell. Virally-encoded miRNAs are one such means to regulate host gene expression in ways that benefit the virus lifecycle. miRNAs are small non-codi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5582de6f9ada35f99f17c375e3720e8
https://pubmed.ncbi.nlm.nih.gov/36463091
https://pubmed.ncbi.nlm.nih.gov/36463091
Autor:
Nicole L. Diggins, Meaghan H. Hancock
Publikováno v:
Non-Coding RNA, Vol 4, Iss 4, p 29 (2018)
It is now well appreciated that microRNAs (miRNAs) play a critical role in the lifecycles of many herpes viruses. The human cytomegalovirus (HCMV) replication cycle varies significantly depending on the cell type infected, with lytic replication occu
Externí odkaz:
https://doaj.org/article/722521a449704d2fb153fa3f6286fc83
Autor:
Meaghan H. Hancock, Jay A. Nelson, Nicole L. Diggins, Lindsey B. Crawford, Jennifer M. Mitchell
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Human cytomegalovirus (HCMV) microRNAs play essential roles in latency and reactivation in CD34+ hematopoietic progenitor cells (HPCs) via regulation of viral and cellular gene expression. In the present study, we show that HCMV miR-US25-1 targets Rh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dc737bb1841a4b4392c69f64d168dc
https://journals.asm.org/doi/10.1128/mBio.00621-21
https://journals.asm.org/doi/10.1128/mBio.00621-21
Autor:
Nicole L, Diggins, Lindsey B, Crawford, Hillary M, Struthers, Lauren M, Hook, Igor, Landais, Rebecca L, Skalsky, Meaghan H, Hancock
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2244
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level by binding to sites within the 3' untranslated regions of messenger RNA (mRNA) transcripts. The discovery of this completely new mechanism of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13b95f63d845c60c614c8f971afb7336
https://pubmed.ncbi.nlm.nih.gov/33555594
https://pubmed.ncbi.nlm.nih.gov/33555594
Autor:
Nicole L. Diggins, Lindsey B. Crawford, Hillary M. Struthers, Lauren M. Hook, Igor Landais, Rebecca L. Skalsky, Meaghan H. Hancock
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f44eb3315ab63af1651e804ce585a39
https://doi.org/10.1007/978-1-0716-1111-1_16
https://doi.org/10.1007/978-1-0716-1111-1_16
Autor:
Meaghan H. Hancock, Jay A. Nelson, Nicole L. Diggins, Jennifer M. Mitchell, Lindsey B. Crawford
Publikováno v:
SSRN Electronic Journal.
Herpesvirus infection of the host results in latency in unique cell-types for each sub-family of viruses. Since herpesviruses are maintained as an episome, the viruses need to devise mechanisms to retain the latent genome during cell division. α-her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27e78f050f336052de8293e3e97c9e56
https://doi.org/10.2139/ssrn.3750130
https://doi.org/10.2139/ssrn.3750130