Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicole L Brockway"'
Autor:
Leah J. Weston, Zoe T. Cook, Teresa L. Stackhouse, Mehtab K. Sal, Baergen I. Schultz, Zachary J.C. Tobias, Valerie R. Osterberg, Nicole L. Brockway, Saheli Pizano, Greta Glover, Tamily A. Weissman, Vivek K. Unni
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105291- (2021)
Abnormal aggregation of the α-synuclein protein is a key molecular feature of Parkinson's disease and other neurodegenerative diseases. The precise mechanisms that trigger α-synuclein aggregation are unclear, and it is not known what role aggregati
Externí odkaz:
https://doaj.org/article/fafe557367834afcb01b5d6e4c898ab3
Autor:
Sylvia Nkombo Nkoula, Helen Ippolito, Zoe T. Cook, Isaac S. Boardman, Zachary J. C. Tobias, Tamily A. Weissman, Joy Pajarla, Nicole L. Brockway
Publikováno v:
Molecular Biology of the Cell
Fluorescent proteins are a powerful experimental tool, allowing the visualization of gene expression and cellular behaviors in a variety of systems. Multicolor combinations of fluorescent proteins, such as Brainbow, have expanded the range of possibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f57156d1df3b128514a31de71ea9735
https://doi.org/10.1091/mbc.e18-06-0340
https://doi.org/10.1091/mbc.e18-06-0340
Publikováno v:
Journal of Visualized Experiments.
Development of the vertebrate nervous system requires a precise coordination of complex cellular behaviors and interactions. The use of high resolution in vivo imaging techniques can provide a clear window into these processes in the living organism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6817d386c2b4d83dc08232a850d830b5
https://doi.org/10.3791/60593
https://doi.org/10.3791/60593
Autor:
Maritte J. O'Gallagher, Nicole L. Brockway, Zoe T. Cook, Kristine M. Carey, Tamily A. Weissman, Mako Gedi, Margaret R. Metz, Zachary J. C. Tobias, Vivek K. Unni, Y. Albert Pan
Publikováno v:
Developmental biology. 453(2)
The global mechanisms that regulate and potentially coordinate cell proliferation & death in developing neural regions are not well understood. In particular, it is not clear how or whether clonal relationships between neural progenitor cells and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fbc1440d5d3769158cbd6a7f9d941e
https://pubmed.ncbi.nlm.nih.gov/31102591
https://pubmed.ncbi.nlm.nih.gov/31102591
Autor:
Nicole L Brockway, Alfonso Schiavi, Hilde Nilsen, Henok Kassahun, Silvia Maglioni, Lars Eide, Hanne Kim Skjeldam, Suzanne Estes, Natascia Ventura, Tanima SenGupta, Katarzyna D. Arczewska
Oxidation of DNA bases, an inevitable consequence of oxidative stress, requires the base excision repair (BER) pathway for repair. Caenorhabditis elegans is a well-established model to study phenotypic consequences and cellular responses to oxidative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c80399f0d2aab54b2cad37ae289fb3
http://hdl.handle.net/10852/66379
http://hdl.handle.net/10852/66379
Autor:
Katherine R. Gentry, Philip G. Morgan, Hyo-Seok Na, Nicole L Brockway, Elyce Opheim, Margaret M. Sedensky
Publikováno v:
Neurotoxicology and teratology. 60
Introduction Neurotoxicity induced by early developmental exposure to volatile anesthetics is a characteristic of organisms across a wide range of species, extending from the nematode C. elegans to mammals. Prevention of anesthetic-induced neurotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a9cdb8b0756067871ff9d510a73c41
https://pubmed.ncbi.nlm.nih.gov/27989695
https://pubmed.ncbi.nlm.nih.gov/27989695
Autor:
Beverley M. Dancy, Yoing Yang, Margaret M. Sedensky, Renjini Ramadasan-Nair, Philip G. Morgan, Nicole L Brockway
Publikováno v:
Mechanisms of ageing and development. 153
To understand primary mitochondrial disease, we utilized a complex I-deficient Caenorhabditis elegans mutant, gas-1. These animals strongly upregulate the expression of gst-14 (encoding a glutathione S-transferase). Knockdown of gst-14 dramatically e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f91ff21d0fead5e5476f9f66b5a6fa
https://pubmed.ncbi.nlm.nih.gov/26704446
https://pubmed.ncbi.nlm.nih.gov/26704446