Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nicole Kuz"'
Publikováno v:
Experimental Brain Research. 157
We evaluated the copying abilities of ten subjects with Williams syndrome (WS; age 6-14 years) and ten normally developing children (age 3-6 years) matched for mental age using the matrices component of the Kaufman Brief Intelligence Test (mKBIT). Ea
Autor:
Maple L. Shiao, Ce Yuan, Andrew T. Crane, Joseph P. Voth, Mario Juliano, Laura L. Hocum Stone, Zhenghong Nan, Ying Zhang, Nicole Kuzmin-Nichols, Paul R. Sanberg, Andrew W. Grande, Walter C. Low
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Our group previously demonstrated that administration of a CD34-negative fraction of human non- hematopoietic umbilical cord blood stem cells (UCBSC) 48 h after ischemic injury could reduce infarct volume by 50% as well as significantly ameliorate ne
Externí odkaz:
https://doaj.org/article/6dc8624213974441a96a7994b986a1fa
Autor:
Laura L. Hocum Stone, Feng Xiao, Jessica Rotschafer, Zhenhong Nan, Mario Juliano, Cyndy D. Sanberg, Paul R. Sanberg, Nicole Kuzmin-Nichols, Andrew Grande, Maxim C-J Cheeran, Walter C. Low Ph.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Despite the high prevalence and devastating outcome, there remain a few options for treatment of ischemic stroke. Currently available treatments are limited by a short time window for treatment and marginal efficacy when used. We have tested a human
Externí odkaz:
https://doaj.org/article/0c344bed19f6483f83aa129faf661edf
Autor:
David J. Eve, Jared Ehrhart, Theresa Zesiewicz, Israt Jahan, Nicole Kuzmin-Nichols, Cyndy Davis Sanberg, Clifton Gooch, Paul R. Sanberg, Svitlana Garbuzova-Davis Ph.D., D.Sc.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by degeneration of motor neurons in the spinal cord and brain. This disease clinically manifests as gradual muscular weakness and atrophy leading to paralysi
Externí odkaz:
https://doaj.org/article/bbf8fee4ce2641bcb5343244ba604b58
Biodistribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model
Autor:
Jared Ehrhart Ph.D., Donna Darlington, Nicole Kuzmin-Nichols, Cyndy D. Sanberg, Darrell R. Sawmiller, Paul R. Sanberg, Jun Tan
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Human umbilical cord blood cells (HUCBCs), a prolific source of non-embryonic or adult stem cells, have emerged as effective and relatively safe immunomodulators and neuroprotectors, reducing behavioral impairment in animal models of Alzheimer's dise
Externí odkaz:
https://doaj.org/article/636b5439111b4304a4020005ae5ee68f
Autor:
Alison E. Willing Ph.D., Svitlana N. Garbuzova-Davis, Olga Zayko, Hiranya M. Derasari, Ashley E. Rawls, Chris R. James, Ron F. Mervis, Cyndy D. Sanberg, Nicole Kuzmin-Nichols, Paul R. Sanberg
Publikováno v:
Cell Transplantation, Vol 23 (2014)
Sanfilippo syndrome type III B (MPS III B) is an inherited disorder characterized by a deficiency of α- N -acetylglucosaminidase (Naglu) enzyme leading to accumulation of heparan sulfate in lysosomes and severe neurological deficits. We have previou
Externí odkaz:
https://doaj.org/article/3a1dbfc86def4d23b29dd76e7210db45
Autor:
Xu Cui, Michael Chopp, Amjad Shehadah, Alex Zacharek, Nicole Kuzmin-Nichols, Cyndy Davis Sanberg, Junhao Dai, Chunling Zhang, Yuji Ueno, Cynthia Roberts, Jieli Chen
Publikováno v:
Cell Transplantation, Vol 21 (2012)
The therapeutic efficacy of cell-based therapy after stroke can be enhanced by making the host brain tissue more receptive to the administered cells, which thereby facilitates brain plasticity. We hypothesized that simvastatin increases human umbilic
Externí odkaz:
https://doaj.org/article/9aa38d61d63c4f7ea5291afceefbdca7
Autor:
Svitlana Garbuzova-Davis, Maria C O Rodrigues, Santhia Mirtyl, Shanna Turner, Shazia Mitha, Jasmine Sodhi, Subatha Suthakaran, David J Eve, Cyndy D Sanberg, Nicole Kuzmin-Nichols, Paul R Sanberg
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31254 (2012)
A promising therapeutic strategy for amyotrophic lateral sclerosis (ALS) is the use of cell-based therapies that can protect motor neurons and thereby retard disease progression. We recently showed that a single large dose (25 × 10⁶ cells) of mono
Externí odkaz:
https://doaj.org/article/86098c600cee4eb8b92635ba7af09fac
Autor:
Svitlana Garbuzova-Davis, Robert L Woods, Michael K Louis, Theresa A Zesiewicz, Nicole Kuzmin-Nichols, Kelly L Sullivan, Amber M Miller, Diana G Hernandez-Ontiveros, Paul R Sanberg
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10614 (2010)
BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) treatment is complicated by the various mechanisms underlying motor neuron degeneration. Recent studies showed that the blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) are compromised in
Externí odkaz:
https://doaj.org/article/c4acc2a4552a4d98aeee3655f4c8126b
Autor:
Svitlana Garbuzova-Davis, Cyndy Davis Sanberg, Nicole Kuzmin-Nichols, Alison E Willing, Carmelina Gemma, Paula C Bickford, Christina Miller, Robert Rossi, Paul R Sanberg
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2494 (2008)
Amyotrophic Lateral Sclerosis (ALS) is a multicausal disease characterized by motor neuron degeneration in the spinal cord and brain. Cell therapy may be a promising new treatment for this devastating disorder. We recently showed that a single low do
Externí odkaz:
https://doaj.org/article/b13ef9c08eee463aaf5d3cc20d9f7dba