Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nicole Kilgore"'
Autor:
Julie A. Ake, Kristopher Paolino, Jack N. Hutter, Susan Biggs Cicatelli, Leigh Anne Eller, Michael A. Eller, Margaret C. Costanzo, Dominic Paquin-Proulx, Merlin L. Robb, Chi L. Tran, Lalaine Anova, Linda L. Jagodzinski, Lucy A. Ward, Nicole Kilgore, Janice Rusnak, Callie Bounds, Christopher S. Badorrek, Jay W. Hooper, Steven A. Kwilas, Ine Ilsbroux, Dickson Nkafu Anumendem, Auguste Gaddah, Georgi Shukarev, Viki Bockstal, Kerstin Luhn, Macaya Douoguih, Cynthia Robinson
Publikováno v:
Vaccines, Vol 12, Iss 5, p 497 (2024)
The safety and immunogenicity of the two-dose Ebola vaccine regimen MVA-BN-Filo, Ad26.ZEBOV, 14 days apart, was evaluated in people without HIV (PWOH) and living with HIV (PLWH). In this observer-blind, placebo-controlled, phase 2 trial, healthy adul
Externí odkaz:
https://doaj.org/article/d508ae26d5664c20827179054ade0b7e
Autor:
Rona Hirschberg, Lucy A. Ward, Nicole Kilgore, Rebecca Kurnat, Helen Schiltz, Mark T. Albrecht, George W. Christopher, Ed Nuzum
Publikováno v:
Viruses, Vol 6, Iss 7, Pp 2673-2697 (2014)
On August 22–23, 2013, agencies within the United States Department of Defense (DoD) and the Department of Health and Human Services (HHS) sponsored the Filovirus Medical Countermeasures (MCMs) Workshop as an extension of the activities of the Filo
Externí odkaz:
https://doaj.org/article/f2ff560aaf2146da970b38c57ebf54d3
Autor:
Edwin O. Nuzum, Nicole Kilgore
Publikováno v:
Viruses, Vol 4, Iss 10, Pp 2312-2316 (2012)
The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics. It is co-led by
Externí odkaz:
https://doaj.org/article/df8ce38712b145c7aacd070f77d6d0b0
Autor:
Julie A. Ake, Kristopher Paolino, Jack N. Hutter, Susan Biggs Cicatelli, Leigh Anne Eller, Michael A. Eller, Margaret C. Costanzo, Dominic Paquin-Proulx, Merlin L. Robb, Chi L. Tran, Lalaine Anova, Linda L. Jagodzinski, Lucy A. Ward, Nicole Kilgore, Janice Rusnak, Callie Bounds, Christopher S. Badorrek, Jay W. Hooper, Steve Kwilas, Ine Ilsbroux, Dickson Nkafu Anumendem, Auguste Gaddah, Georgi Shukarev, Viki Bockstal, Kerstin Luhn, Macaya Douoguih, Cynthia Robinson
Publikováno v:
SSRN Electronic Journal.
Autor:
W. Jay Ramsey, Donna MacKinnon-Cameron, Catherine Brown, Steven A Kwilas, Scott A. Halperin, D. Gray Heppner, Tracy Kemp, Teresa Nowak, Li Li, Thomas P. Monath, May Elsherif, Jay W. Hooper, Shelly A. McNeil, Carol Sabourin, Christopher S. Badorrek, Trina Racine, Peter Silvera, Thomas L. Rudge, Nicole Kilgore, Judie Alimonti, Joanne M. Langley
Publikováno v:
Canadian Medical Association Journal. 189:E819-E827
BACKGROUND: The 2013–2016 Ebola virus outbreak in West Africa was the most widespread in history. In response, alive attenuated recombinant vesicular stomatitis virus (rVSV) vaccine expressing Zaire Ebolavirus glycoprotein (rVSVΔG-ZEBOV-GP) was ev
Autor:
Lucy A. Ward, George W. Christopher, Rona Hirschberg, Rebecca Kurnat, Ed Nuzum, Nicole Kilgore, Helen Schiltz, Mark T. Albrecht
Publikováno v:
Viruses, Vol 6, Iss 7, Pp 2673-2697 (2014)
Viruses
Viruses
On August 22–23, 2013, agencies within the United States Department of Defense (DoD) and the Department of Health and Human Services (HHS) sponsored the Filovirus Medical Countermeasures (MCMs) Workshop as an extension of the activities of the Filo
Elevated temperature triggers human respiratory syncytial virus F protein six-helix bundle formation
Autor:
Katherine Crisafi, Abdul S. Yunus, Karl Salzwedel, Nicole Kilgore, Dorian Zoumplis, Carl T. Wild, Trent P. Jackson, Graham P. Allaway, Irina Burimski
Publikováno v:
Virology
Human respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infection in infants, immunocompromised patients, and the elderly. The RSV fusion (F) protein mediates fusion of the viral envelope with the target cell membra
Autor:
Keduo Qian, Nicole Kilgore, Susan L. Morris-Natschke, Graham P. Allaway, Kuo Hsiung Lee, Donglei Yu, Kyoko Nakagawa-Goto, Theodore J. Nitz
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:6553-6557
3-O-3′(or 2′)-Methylsuccinyl-betulinic acid (MSB) derivatives were separated by using recycle HPLC. The structures of four isomers were assigned by NMR and asymmetric synthesis. 3-O-3′S-Methylsuccinyl-betulinic acid (3′S-MSB, 4) exhibited pot
Autor:
Susan L. Morris-Natschke, Yi Xia, Yang Wang, Nicole Kilgore, Peng Xia, Shao Xu Huang, Zheng Yu Yang, Kuo Hsiung Lee
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:4316-4319
3′,4′-Di-O-(−)-camphanoyl-(+)-cis-khellactone (DCK, 1) demonstrated extremely potent inhibitory activity against HIV-1 replication in H9 lymphocytic cells with an EC50 value of 2.56 × 10−4 μM and a therapeutic index (TI) of 1.37 × 105 in o
Autor:
Karl Salzwedel, Eric O. Freed, Dorian Zoumplis, Feng Li, Catherine S. Adamson, Abdul S. Yunus, Claudia Matallana, Nicole Kilgore, David E. Martin, Mary Reddick, Graham P. Allaway, Carl T. Wild
Publikováno v:
Virology. 356(1-2):217-224
3-O-(3′,3′-dimethylsuccinyl) betulinic acid, also termed PA-457 or DSB, is a novel HIV-1 inhibitor that blocks virus maturation by disrupting cleavage of the capsid precursor, CA-SP1. To better define the molecular target for PA-457, we prepared