Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nicole K. Littlejohn"'
Autor:
Bernard P. Kok, Andrea Galmozzi, Nicole K. Littlejohn, Verena Albert, Cristina Godio, Woojoo Kim, Sean M. Kim, Jeffrey S. Bland, Neile Grayson, Mingliang Fang, Wolfgang Meyerhof, Gary Siuzdak, Supriya Srinivasan, Maik Behrens, Enrique Saez
Publikováno v:
Molecular Metabolism, Vol 16, Iss , Pp 76-87 (2018)
Objectives: Extracts of the hops plant have been shown to reduce weight and insulin resistance in rodents and humans, but elucidation of the mechanisms responsible for these benefits has been hindered by the use of heterogeneous hops-derived mixtures
Externí odkaz:
https://doaj.org/article/13cb3da1ba1b47f5b449b4d9690f02b2
Autor:
Nicole K. Littlejohn, Henry L. Keen, Benjamin J. Weidemann, Kristin E. Claflin, Kevin V. Tobin, Kathleen R. Markan, Sungmi Park, Meghan C. Naber, Francoise A. Gourronc, Nicole A. Pearson, Xuebo Liu, Donald A. Morgan, Aloysius J. Klingelhutz, Matthew J. Potthoff, Kamal Rahmouni, Curt D. Sigmund, Justin L. Grobe
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1548-1560 (2016)
Activation of the brain renin-angiotensin system (RAS) stimulates energy expenditure through increasing of the resting metabolic rate (RMR), and this effect requires simultaneous suppression of the circulating and/or adipose RAS. To identify the mech
Externí odkaz:
https://doaj.org/article/e7234e0f403b4ffda221e675b42b26a6
Autor:
Enrique Saez, Supriya Srinivasan, Jeffrey S. Bland, Sean M. Kim, Neile Grayson, Gary Siuzdak, C. Godio, Woojoo Kim, Maik Behrens, Bernard P. Kok, Wolfgang Meyerhof, Verena Albert, Mingliang Fang, Andrea Galmozzi, Nicole K. Littlejohn
Publikováno v:
Molecular Metabolism, Vol 16, Iss, Pp 76-87 (2018)
Objectives: Extracts of the hops plant have been shown to reduce weight and insulin resistance in rodents and humans, but elucidation of the mechanisms responsible for these benefits has been hindered by the use of heterogeneous hops-derived mixtures
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The relationship between lipid metabolism and longevity remains unclear. Although fat oxidation is essential for weight loss, whether it remains beneficial when sustained for long periods, and the extent to which it may attenuate or augment lifespan
SUMMARYThe relationship between lipid metabolism and longevity remains unclear. In particular although fat oxidation is essential for weight loss, whether it is remains beneficial when sustained for long periods, and the extent to which it may alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9113ec85af6ae6102fbd467d6449827c
https://doi.org/10.1101/2020.05.17.100594
https://doi.org/10.1101/2020.05.17.100594
Autor:
Allyn M. Lambertz, Katherine N. Gibson-Corley, Jeremy A. Sandgren, Benjamin J. Weidemann, Nicole A Pearson, Nicole K. Littlejohn, Colin M.L. Burnett, Kristin E. Claflin, Donald A. Morgan, Kamal Rahmouni, Justin L. Grobe
Publikováno v:
Journal of Clinical Investigation. 127:1414-1424
Leptin contributes to the control of resting metabolic rate (RMR) and blood pressure (BP) through its actions in the arcuate nucleus (ARC). The renin-angiotensin system (RAS) and angiotensin AT1 receptors within the brain are also involved in the con
Autor:
Aloysius J. Klingelhutz, Nicole K. Littlejohn, Kamal Rahmouni, Kevin V. Tobin, Justin L. Grobe, Meghan C. Naber, Nicole A Pearson, Matthew J. Potthoff, Benjamin J. Weidemann, Francoise A. Gourronc, Xuebo Liu, Kathleen R. Markan, Sungmi Park, Kristin E. Claflin, Donald A. Morgan, Henry L. Keen, Curt D. Sigmund
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1548-1560 (2016)
SummaryActivation of the brain renin-angiotensin system (RAS) stimulates energy expenditure through increasing of the resting metabolic rate (RMR), and this effect requires simultaneous suppression of the circulating and/or adipose RAS. To identify t
Autor:
Justin L. Grobe, Nicole K Littlejohn
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Metabolic disease, specifically obesity, has now become the greatest challenge to improving cardiovascular health. The renin-angiotensin system (RAS) exists as both a circulating hormone system and as a local paracrine signaling mechanism within vari
Autor:
Curt D. Sigmund, Matthew D Folchert, Kamal Rahmouni, Nicole K. Littlejohn, Javier Gomez, Justin L. Grobe, Pablo Nakagawa, Benjamin J. Weidemann, Laura L. Boles Ponto, Susan A. Walsh, Donald A. Morgan, Xuebo Liu, Keisuke Shinohara
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 70(5)
The brain-specific isoform of renin (Ren-b) has been proposed as a negative regulator of the brain renin–angiotensin system (RAS). We analyzed mice with a selective deletion of Ren-b which preserved expression of the classical renin (Ren-a) isoform