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pro vyhledávání: '"Nicole Köger"'
Autor:
Antje M. Richter, Steffen Kiehl, Nicole Köger, Janina Breuer, Thorsten Stiewe, Reinhard H. Dammann
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-12 (2017)
Abstract Background Lung cancer is the leading cause of cancer-related deaths with 1.8 million new cases each year and poor 5-year prognosis. Promoter hypermethylation of tumour suppressors leads to their inactivation and thereby can promote cancer d
Externí odkaz:
https://doaj.org/article/b953bc56758d461faa9e60f8787adfd2
Publikováno v:
Human mutation. 40(4)
The human DNA repair gene MUTYH, whose mutational loss causes a colorectal polyposis and cancer predisposition, contains three alternative first exons. In order to analyze alternative transcription and the effect of genetic alterations found in human
Autor:
Thorsten Stiewe, Antje M. Richter, Reinhard Dammann, Janina Breuer, Steffen Kiehl, Nicole Köger
Publikováno v:
Clinical Epigenetics
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-12 (2017)
Clinical Epigenetics 9:60 doi: 10.1186/s13148-017-0360-4
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-12 (2017)
Clinical Epigenetics 9:60 doi: 10.1186/s13148-017-0360-4
Background Lung cancer is the leading cause of cancer-related deaths with 1.8 million new cases each year and poor 5-year prognosis. Promoter hypermethylation of tumour suppressors leads to their inactivation and thereby can promote cancer developmen
Autor:
Gabriel Capellá, Laura Valle, Fernando Bellido, Matilde Navarro, Guido Plotz, Olga Campos, Rafael Valdés-Mas, Xose S. Puente, Conxi Lázaro, Marta Pineda, Marta Gut, Adriana Lopez-Doriga, Sara González, Nicole Köger, Silvia Iglesias, Ignacio Blanco, Nuria Seguí
Publikováno v:
Gut. 64:355-356
Ma et al 1 comprehensively assessed the association of previously reported genetic variants with colorectal cancer (CRC) risk. The meta-analyses revealed strong evidence for association with rare MUTYH variants, even when excluding cases with MUTYH-a