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pro vyhledávání: '"Nicole J. Neverman"'
Autor:
Hannah L Best, Nicole J Neverman, Hollie E Wicky, Nadia L Mitchell, Beulah Leitch, Stephanie M Hughes
Publikováno v:
Neurobiology of Disease, Vol 100, Iss , Pp 62-74 (2017)
Batten disease (neuronal ceroid lipofuscinosis) refers to a group of neurodegenerative lysosomal storage diseases predominantly affecting children. There are currently no effective treatments, and the functions of many of the associated gene products
Externí odkaz:
https://doaj.org/article/d41179562f024cc48573499b633dc120
Autor:
Beulah Leitch, Stephanie M. Hughes, Hollie E Wicky, Nadia L. Mitchell, Hannah L Best, Nicole J. Neverman
Publikováno v:
Neurobiology of Disease, Vol 100, Iss, Pp 62-74 (2017)
Batten disease (neuronal ceroid lipofuscinosis) refers to a group of neurodegenerative lysosomal storage diseases predominantly affecting children. There are currently no effective treatments, and the functions of many of the associated gene products
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1852:2292-2300
The neuronal ceroid lipofuscinoses represent a group of severe childhood lysosomal storage diseases. With at least 13 identified variants they are the most common cause of inherited neurodegeneration in children. These diseases share common pathologi
Recent studies of ovine neuronal ceroid lipofuscinoses from BARN, the Batten Animal Research Network
Autor:
Nadia L. Mitchell, Jarol Z. Chen, Peter J. Houweling, David Palmer, Chia-Tien Chang, Lucy A. Barry, Imke Tammen, Nicole J. Neverman, Stephanie M. Hughes
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1852:2279-2286
Studies on naturally occurring New Zealand and Australian ovine models of the neuronal ceroid-lipofuscinoses (Batten disease, NCLs) have greatly aided our understanding of these diseases. Close collaborations between the New Zealand groups at Lincoln