Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Nicole J. De Nisco"'
Autor:
Namrata V. Sawant, Samuel S. Chang, Krutika A. Pandit, Prachi Khekare, W. Randolph Warner, Philippe E. Zimmern, Nicole J. De Nisco
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTManagement of urinary tract infection (UTI) in postmenopausal women can be challenging. The recent rise in resistance to most of the available oral antibiotic options together with high recurrence rate in postmenopausal women has further comp
Externí odkaz:
https://doaj.org/article/ad869ce94f7d404b84f468949b9320a7
Autor:
Belle M. Sharon, Amanda P. Arute, Amber Nguyen, Suman Tiwari, Sri Snehita Reddy Bonthu, Neha V. Hulyalkar, Michael L. Neugent, Dennise Palacios Araya, Nicholas A. Dillon, Philippe E. Zimmern, Kelli L. Palmer, Nicole J. De Nisco
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTEnterococcus faecalis is the leading Gram-positive bacterial species implicated in urinary tract infection (UTI). An opportunistic pathogen, E. faecalis is a commensal of the human gastrointestinal tract (GIT), and its presence in the GIT is
Externí odkaz:
https://doaj.org/article/1e08489298e6422abb8f77d499496757
Autor:
James F. Colbert, Joshua M. Kirsch, Christopher L. Erzen, Christophe J. Langouët-Astrié, Grace E. Thompson, Sarah A. McMurtry, Jennifer M. Kofonow, Charles E. Robertson, Elizabeth J. Kovacs, Ryan C. Sullivan, Joseph A. Hippensteel, Namrata V. Sawant, Nicole J. De Nisco, Bruce D. McCollister, Robert S. Schwartz, Alexander R. Horswill, Daniel N. Frank, Breck A. Duerkop, Eric P. Schmidt
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Prior research has focused on host factors as mediators of exaggerated sepsis-associated morbidity and mortality in older adults. This focus on the host, however, has failed to identify therapies that improve sepsis outcomes in the elderly.
Externí odkaz:
https://doaj.org/article/3534f0ab7eb1418a8befb8cb4e008912
Autor:
Antra Ganguly, Tahmineh Ebrahimzadeh, Jessica Komarovsky, Philippe E. Zimmern, Nicole J. De Nisco, Shalini Prasad
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract In this work, we propose a novel diagnostic workflow—DigEST—that will enable stratification of disease states based on severity using multiplexed point of care (POC) biosensors. This work can boost the performance of current POC tests by
Externí odkaz:
https://doaj.org/article/f088a04b03aa44a6bf64320989d3cdc3
Publikováno v:
Frontiers in Applied Mathematics and Statistics, Vol 8 (2022)
In the last decade, numerous statistical methods have been developed for analyzing microbiome data generated from high-throughput next-generation sequencing technology. Microbiome data are typically characterized by zero inflation, overdispersion, hi
Externí odkaz:
https://doaj.org/article/2a8df2362e784b6c8016681f79016ed3
Autor:
Vivian H. Nguyen, Fatima Khan, Braden M. Shipman, Michael L. Neugent, Neha V. Hulyalkar, Natalie Y. Cha, Philippe E. Zimmern, Nicole J. De Nisco
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Glycosaminoglycans (GAGs) are linear polysaccharides and are among the primary components of mucosal surfaces in mammalian systems. The GAG layer lining the mucosal surface of the urinary tract is thought to play a critical role in urinary tract home
Externí odkaz:
https://doaj.org/article/6e819979668846b798b28a4c7f542041
Autor:
Nicole J. De Nisco, Amanda K. Casey, Mohammed Kanchwala, Alexander E. Lafrance, Fatma S. Coskun, Lisa N. Kinch, Nick V. Grishin, Chao Xing, Kim Orth
Publikováno v:
mSystems, Vol 6, Iss 1 (2021)
ABSTRACT Diverse bacterial pathogens employ effector delivery systems to disrupt vital cellular processes in the host (N. M. Alto and K. Orth, Cold Spring Harbor Perspect Biol 4:a006114, 2012, https://doi.org/10.1101/cshperspect.a006114). The type II
Externí odkaz:
https://doaj.org/article/f1dba263d2f44ae5a737a1c52f6e5004
Autor:
Michael L. Neugent, Neha V. Hulyalkar, Vivian H. Nguyen, Philippe E. Zimmern, Nicole J. De Nisco
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Recent advances in the analysis of microbial communities colonizing the human body have identified a resident microbial community in the human urinary tract (UT). Compared to many other microbial niches, the human UT harbors a relatively low
Externí odkaz:
https://doaj.org/article/0d3702d383b04b7fb9afdd28ba07e787
Autor:
Antra Ganguly, Tahmineh Ebrahimzadeh, Philippe E. Zimmern, Nicole J. De Nisco, Shalini Prasad
Publikováno v:
Chemosensors, Vol 9, Iss 9, p 271 (2021)
A label-free, rapid, and easy-to-use lateral flow electrochemical biosensor was developed for urinary tract infection (UTI) diagnosis in resource challenged areas. The sensor operates in non-faradaic mode and utilizes Electrochemical Impedance Spectr
Externí odkaz:
https://doaj.org/article/46e6153d17ed41848677fb4b75f61d0e
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Enteric pathogens employ sophisticated strategies to colonize and infect mammalian hosts. Gram-negative bacteria, such as Escherichia coli, Salmonella, and Campylobacter jejuni, are among the leading causes of gastrointestinal tract infectio
Externí odkaz:
https://doaj.org/article/986a9a34dfcd440a930df17d7ba0513e