Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Nicole J Sylvain"'
Autor:
Sally Caine, Mark J. Hackett, Huishu Hou, Saroj Kumar, Jason Maley, Zurab Ivanishvili, Brandon Suen, Aleksander Szmigielski, Zhongxiang Jiang, Nicole J. Sylvain, Helen Nichol, Michael E. Kelly
Publikováno v:
Neurobiology of Disease, Vol 91, Iss , Pp 132-142 (2016)
Stroke is a major global health problem, with the prevalence and economic burden predicted to increase due to aging populations in western society. Following stroke, numerous biochemical alterations occur and damage can spread to nearby tissue. This
Externí odkaz:
https://doaj.org/article/71b772721d6542b394db040cca16d574
Autor:
Nicole J Sylvain, Michael Pushie, Huishu Hou, Claire N DuVal, Sally Caine, Mark J Hackett, Michael E Kelly
Publikováno v:
Stroke. 54
Introduction: Cerebral ischemia results in a lesion comprised of dying cells surrounded by a band of tissue containing cells at risk of dying, called the penumbra. Understanding the status of energy metabolism in the stroke is necessary to get a clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e45440c8ad1a155d3aad1c59da292f27
https://doi.org/10.1161/str.54.suppl_1.102
https://doi.org/10.1161/str.54.suppl_1.102
Publikováno v:
Metallomics
Synchrotron-based X-ray fluorescence microscopy is a flexible tool for identifying the distribution of trace elements in biological specimens across a broad range of sample sizes. The technique is not particularly limited by sample type and can be pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c43bcf2a414c62264c955c2b5153b68
https://doi.org/10.1093/mtomcs/mfac032
https://doi.org/10.1093/mtomcs/mfac032
Autor:
Huishu Hou, Massimiliano Massi, Thomas Becker, David Hartnell, Elizabeth Watkin, Nicole J. Sylvain, Anna Maria Ranieri, Jitraporn Vongsvivut, Michael Kelly, Keith R. Bambery, Mark J. Tobin, Hum Bahadur Lamichhane, M. Jake Pushie, Ashley Hollings, Mark J. Hackett
Publikováno v:
The Analyst. 146:3516-3525
Visualising direct biochemical markers of cell physiology and disease pathology at the sub-cellular level is an ongoing challenge in the biological sciences. A suite of microscopies exists to either visualise sub-cellular architecture or to indirectl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d257a9633acb32172b36755a8a43bbf
https://doi.org/10.1039/d1an00136a
https://doi.org/10.1039/d1an00136a
Autor:
George J Sopasis, Graham N. George, Ingrid J. Pickering, Hugh H. Harris, Nicole J. Sylvain, Barry Lai, Natalia V. Dolgova, Ashley K. James, Helen Nichol, Kelly L. Summers, Kenneth B. Gagnon
Publikováno v:
Metallomics. 12:1979-1994
8-Hydroxyquinolines (8HQs) comprise a family of metal-binding compounds that have been used or tested for use in numerous medicinal applications, including as treatments for bacterial infection, Alzheimer's disease, and cancer. Two key 8HQs, CQ (5-ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6088a1029ed092151261dcd1d966cfe0
https://doi.org/10.1039/d0mt00222d
https://doi.org/10.1039/d0mt00222d
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Stroke is a leading cause of long-term disability in adults and a leading cause of death in developed nations. The cascade of cellular events and signalling that occur after cerebral ischemia are complex, however, analyzing global element markers of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b17c711e73af95646992c29dca0d83d
http://link.springer.com/article/10.1038/s41598-020-74698-2
http://link.springer.com/article/10.1038/s41598-020-74698-2
Autor:
Kate Gillespie-Jones, M. J. Pushie, Michael Kelly, Dasuni S. Alwis, Massimiliano Massi, Nicole J. Sylvain, David Hartnell, Ramesh Rajan, Bradley J Schwehr, Huishu Hou, Mark J. Hackett
Publikováno v:
The Analyst. 145:3809-3813
The effect of halogen substitution in fluorescent BODIPY species was evaluated in the context of staining lipids in situ within brain tissue sections. Herein we demonstrate that the halogenated species maintain their known in vitro affinity when appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21824e5032beac6788c3cafbf427d041
https://doi.org/10.1039/d0an00099j
https://doi.org/10.1039/d0an00099j
Autor:
Michael Kelly, Andrew M. Crawford, Huishu Hou, Nicole J. Sylvain, Mark J. Hackett, Ingrid J. Pickering, Graham N. George, M. Jake Pushie
Publikováno v:
Journal of Synchrotron Radiation. 25:1780-1789
Synchrotron X-ray fluorescence imaging enables visualization and quantification of microscopic distributions of elements. This versatile technique has matured to the point where it is used in a wide range of research fields. The method can be used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f75b6d00fc334dce7ef89c72af9a64
https://doi.org/10.1107/s1600577518010895
https://doi.org/10.1107/s1600577518010895
Autor:
Mark J. Hackett, Michael Kelly, Andrew M. Crawford, Huishu Hou, Graham N. George, M. Jake Pushie, Nicole J. Sylvain
Publikováno v:
ACS Chemical Neuroscience. 9:886-893
Stroke exacts a heavy financial and economic burden, is a leading cause of death, and is the leading cause of long-term disability in those who survive. The penumbra surrounds the ischemic core of the stroke lesion and is composed of cells that are s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cb0d17df5cb93432eb113201f79f61
https://doi.org/10.1021/acschemneuro.7b00382
https://doi.org/10.1021/acschemneuro.7b00382
Publikováno v:
Journal of Archaeological Science: Reports. 16:430-440
The Franklin Expedition (1845–1848) left in search of the Northwest Passage and ended tragically with the loss of all crew members. Mystery surrounds their ultimate fate, with particular speculation around the role of lead poisoning. Our unique stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22fc40ab0a4f6383f34226ec497b1d8
https://doi.org/10.1016/j.jasrep.2016.11.042
https://doi.org/10.1016/j.jasrep.2016.11.042