Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicole J, Yang"'
Autor:
Nicole J. Yang, Dylan V. Neel, Liwen Deng, Michelle Heyang, Angela Kennedy-Curran, Victoria S. Tong, Jin Mo Park, Isaac M. Chiu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Bacterial products are able to act on nociceptive neurons during pathogenic infection. Neurogenic inflammation is an active part of pain signaling and has recently been shown to impact host-pathogen defense. Bacillus anthracis Edema Toxin (ET) produc
Externí odkaz:
https://doaj.org/article/e240264f8dfc435faf6001284ed28aaf
Autor:
Nicole J, Yang
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2491
Yeast surface display is a robust platform for obtaining binders with high affinity. Kinetic competition screening is an effective method for maturing the affinity of binders with strong starting affinities, or when dissociation kinetics are a key co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2244f2187e71fbe5d551b0dc88535e47
https://pubmed.ncbi.nlm.nih.gov/35482187
https://pubmed.ncbi.nlm.nih.gov/35482187
Autor:
Benjamin Salzer, Irene Schaffner, Kristina Djinović-Carugo, Michael W. Traxlmayr, Annika De Sousa Linhares, Wolfgang Holter, Manfred Lehner, Peter Steinberger, Nicole J. Yang, Christian Obinger, Charlotte U. Zajc, Markus Dobersberger, G. Mlynek, Dominic Pühringer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Molecular ON-switches are important tools in chemical biology, enabling protein–protein interactions to be regulated by small molecules. However, currently available ON-switches that induce conditional heterodimerization are suboptimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7f8213a9d6b594eef65dc5a3b709dc
http://europepmc.org/articles/PMC7334647
http://europepmc.org/articles/PMC7334647
Autor:
Nicole J. Yang
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::777081b726525bd5e6c08bb0857fbebb
https://doi.org/10.1007/978-1-0716-2285-8_6
https://doi.org/10.1007/978-1-0716-2285-8_6
Autor:
Nicole J. Yang, Jörg Isensee, Dylan V. Neel, Andreza U. Quadros, Han-Xiong Bear Zhang, Justas Lauzadis, Sai Man Liu, Stephanie Shiers, Andreea Belu, Shilpa Palan, Sandra Marlin, Jacquie Maignel, Angela Kennedy-Curran, Victoria S. Tong, Mahtab Moayeri, Pascal Röderer, Anja Nitzsche, Mike Lu, Bradley L. Pentelute, Oliver Brüstle, Vineeta Tripathi, Keith A. Foster, Theodore J. Price, R. John Collier, Stephen H. Leppla, Michelino Puopolo, Bruce P. Bean, Thiago M. Cunha, Tim Hucho, Isaac M. Chiu
Publikováno v:
Nat Neurosci
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Bacterial products can act on neurons to alter signaling and function. Here, we find that dorsal root ganglia (DRG) sensory neurons are enriched for ANTXR2, the high-affinity receptor for anthrax toxins. Anthrax toxins are composed of protective anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51535d2a537fb4d96983bf570b33773
https://europepmc.org/articles/PMC9388775/
https://europepmc.org/articles/PMC9388775/
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 3, Iss C (2014)
Protein-based methods of targeted short-interfering RNA (siRNA) delivery have the potential to solve some of the problems faced by nanoparticle-based methods, such as poor pharmacokinetics and biodistribution, low tumor penetration, and polydispersit
Externí odkaz:
https://doaj.org/article/a9df14352b8146aca5bff68fc97be7ec
Autor:
Nicole J, Yang, Jörg, Isensee, Dylan V, Neel, Andreza U, Quadros, Han-Xiong Bear, Zhang, Justas, Lauzadis, Sai Man, Liu, Stephanie, Shiers, Andreea, Belu, Shilpa, Palan, Sandra, Marlin, Jacquie, Maignel, Angela, Kennedy-Curran, Victoria S, Tong, Mahtab, Moayeri, Pascal, Röderer, Anja, Nitzsche, Mike, Lu, Bradley L, Pentelute, Oliver, Brüstle, Vineeta, Tripathi, Keith A, Foster, Theodore J, Price, R John, Collier, Stephen H, Leppla, Michelino, Puopolo, Bruce P, Bean, Thiago M, Cunha, Tim, Hucho, Isaac M, Chiu
Publikováno v:
Nature neuroscience. 25(2)
Bacterial products can act on neurons to alter signaling and function. In the present study, we found that dorsal root ganglion (DRG) sensory neurons are enriched for ANTXR2, the high-affinity receptor for anthrax toxins. Anthrax toxins are composed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6971ca098e230bc53d17d96858b19c75
https://pubmed.ncbi.nlm.nih.gov/34931071
https://pubmed.ncbi.nlm.nih.gov/34931071
Autor:
Oliver Brüstle, Anja Nitzsche, Nicole J. Yang, Jin Mo Park, R. John Collier, Tim Hucho, Dylan V. Neel, Andreea Belu, Bruce P. Bean, Vineeta Tripathi, Jörg Isensee, Isaac M. Chiu, Shilpa Palan, Mike Lu, Pascal Röderer, Bradley L. Pentelute, Keith Foster, Stephen H. Leppla, Sai Man Liu, Angela Kennedy-Curran, Han Xiong Bear Zhang
Bacterial toxins are able to act on neurons to modulate signaling and function. Here, we find that nociceptive sensory neurons that mediate pain are enriched in the receptor for anthrax toxins, ANTXR2. Anthrax Edema Toxin (ET) induced cAMP and PKA si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c5e2877166f206fe26a06b97f4b2e8
Autor:
Fangdi Sun, Katie F. Maass, Nicole J. Yang, Monique J. Kauke, Yao Yu, K. Dane Wittrup, Lucy F. Yang, Michael W. Traxlmayr, Yingda Xu, Robert Langer, Daniel G. Anderson
Publikováno v:
Nucleic Acids Research
Protein-based methods of siRNA delivery are capable of uniquely specific targeting, but are limited by technical challenges such as low potency or poor biophysical properties. Here, we engineered a series of ultra-high affinity siRNA binders based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b3c3f0537100c11212892ce706fc2f
https://doi.org/10.1093/nar/gkx546
https://doi.org/10.1093/nar/gkx546
Autor:
Mikhail Kalinichev, John A. Chaddock, Sandra Marlin, Keith Foster, R. John Collier, Michelle Heyang, Isaac M. Chiu, Tiphaine Voisin, Vineeta Tripathi, Nicole J. Yang, Agnieszka Lewandowska, Sai Man Liu
Publikováno v:
Toxicon. 156:S118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c76e08dd64f91fd27bbeece4b36c39b
https://doi.org/10.1016/j.toxicon.2018.11.282
https://doi.org/10.1016/j.toxicon.2018.11.282