Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Nicole J, Moreland"'
Autor:
Natalie Lorenz, Reuben McGregor, Alana L. Whitcombe, Prachi Sharma, Ciara Ramiah, Francis Middleton, Michael G. Baker, William J. Martin, Nigel J. Wilson, Amy W. Chung, Nicole J. Moreland
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110558- (2024)
Summary: Understanding the immune profile of acute rheumatic fever (ARF), a serious post-infectious sequelae of Streptococcal pyogenes (group A Streptococcus [GAS]), could inform disease pathogenesis and management. Circulating cytokines, immunoglobu
Externí odkaz:
https://doaj.org/article/b13c75f917df48d4a74aa75b9fe44bec
Autor:
Jake A. Lacey, Julie Bennett, Taylah B. James, Benjamin S. Hines, Tiffany Chen, Darren Lee, Dianne Sika-Paotonu, Anneka Anderson, Matire Harwood, Steven Y.C. Tong, Michael G. Baker, Deborah A. Williamson, Nicole J. Moreland
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 42, Iss , Pp 100964- (2024)
Summary: Background: Acute rheumatic fever (ARF) is a serious post-infectious sequala of Group A Streptococcus (GAS, Streptococcus pyogenes). In New Zealand (NZ) ARF is a major cause of health inequity. This study describes the genomic analysis of GA
Externí odkaz:
https://doaj.org/article/06cb3ed34907416fba84ce4a283d15aa
Autor:
Jeremy M. Raynes, Paul G. Young, Natalie Lorenz, Jacelyn M.S. Loh, Reuben McGregor, Edward N. Baker, Thomas Proft, Nicole J. Moreland
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTGroup A Streptococcus (GAS) is a globally important pathogen causing a broad range of human diseases. GAS pili are elongated proteins with a backbone comprised repeating T-antigen subunits, which extend from the cell surface and have importan
Externí odkaz:
https://doaj.org/article/30a4e018f51b48a6a8ed8bcce2a52dfb
Autor:
Reuben McGregor, Aimee Paterson, Prachi Sharma, Tiffany Chen, Jarrod R. Lovell, Lauren H. Carlton, Andrew C. Steer, Joshua Osowicki, Jacelyn M. S. Loh, Nicole J. Moreland
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Group A Streptococcus (GAS) is a leading human pathogen for which there is no licensed vaccine. Infections are most common in young children and the elderly suggesting immunity accumulates with exposure until immune senescence in older age.
Externí odkaz:
https://doaj.org/article/e25b86a43fe942aa96e12a82aa053f80
Autor:
Farina Nor Hashimi, Julie Bennett, Michael G. Baker, Nicole J. Moreland, Troy L. Merry, Jacelyn M. S. Loh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-5 (2022)
Abstract The number of sugar-sweetened beverages consumed per day has been associated with an increased risk of acute rheumatic fever, an autoimmune disease triggered by superficial Streptococcus pyogenes infection. To explore if there could be a bio
Externí odkaz:
https://doaj.org/article/774a0a6ea62b4c92bc7090696dd8413b
Autor:
Julie Bennett, Nicole J. Moreland, Jane Zhang, Julian Crane, Dianne Sika-Paotonu, Jonathan Carapetis, Deborah A. Williamson, Michael G. Baker
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 26, Iss , Pp 100507- (2022)
Summary: Background: Group A streptococcal (GAS) infections can trigger an immune-mediated response resulting in acute rheumatic fever (ARF). The role of social and environmental risk factors for GAS pharyngitis and skin infections are not well under
Externí odkaz:
https://doaj.org/article/8535974f070e4b2a87e59e0de54cc593
Autor:
Jeffrey W. Cannon, Jane Zhung, Julie Bennett, Nicole J. Moreland, Michael G. Baker, Elizabeth Geelhoed, John Fraser, Jonathan R. Carapetis, Susan Jack
Publikováno v:
International Journal of Infectious Diseases, Vol 103, Iss , Pp 176-181 (2021)
Objectives: In preparation for the future arrival of a group A Streptococcus (GAS) vaccine, this study estimated the economic and health burdens of GAS diseases in New Zealand (NZ). Methods: The annual incidence of GAS diseases was based on extrapola
Externí odkaz:
https://doaj.org/article/9394fa4aa9b646af89ff4ba900546dc4
Autor:
Jacelyn M. S. Loh, Tania Rivera-Hernandez, Reuben McGregor, Adrina Hema J. Khemlani, Mei Lin Tay, Amanda J. Cork, Jeremy M. Raynes, Nicole J. Moreland, Mark J. Walker, Thomas Proft
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Pili of Group A Streptococcus (GAS) are surface-exposed structures involved in adhesion and colonisation of the host during infection. The major protein component of the GAS pilus is the T-antigen, which multimerises to form the pilus shaft.
Externí odkaz:
https://doaj.org/article/e5c26595d82b49ec87d8e1591a0db673
Autor:
David Broadhurst, Bo Remenyi, Timothy C Barnett, Jonathan R Carapetis, Jennifer Yan, Anna P Ralph, Glenn Pearson, Mark Mayo, Rachel Webb, Nicole J Moreland, Reuben McGregor, Anthony Bosco, Timo Lassmann, Rym Benothman, Julie Bennett, Nigel Wilson
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/34b89065999e4c2685d5eccece97fb16
Autor:
Joshua Osowicki, MBBS, Kristy I Azzopardi, BSc, Loraine Fabri, MD, Hannah R Frost, PhD, Tania Rivera-Hernandez, PhD, Melanie R Neeland, PhD, Alana L Whitcombe, BSc, Anneke Grobler, PhD, Sarah J Gutman, MBBS, Ciara Baker, MSc, Janet M F Wong, MBBS, Jason D Lickliter, PhD, Claire S Waddington, PhD, Manisha Pandey, PhD, Tibor Schuster, PhD, Allen C Cheng, ProfPhD, Andrew J Pollard, ProfPhD, James S McCarthy, ProfMD, Michael F Good, ProfPhD, James B Dale, ProfMD, Michael Batzloff, PhD, Nicole J Moreland, PhD, Mark J Walker, ProfPhD, Jonathan R Carapetis, ProfPhD, Pierre R Smeesters, ProfPhD, Andrew C Steer, ProfPhD
Publikováno v:
The Lancet Microbe, Vol 2, Iss 7, Pp e291-e299 (2021)
Summary: Background: Streptococcus pyogenes is a leading cause of infection-related morbidity and mortality. A reinvigorated vaccine development effort calls for new clinically relevant human S pyogenes experimental infection models to support proof
Externí odkaz:
https://doaj.org/article/ec41c56b2f5e46caa2cee686d70a813b