Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Nicole I, Zur Nieden"'
Publikováno v:
Toxics, Vol 11, Iss 12, p 998 (2023)
Tobacco smoke contains between 7000 and 10,000 constituents, and only an evanescently low number of which have been identified, let alone been evaluated for their toxicity. Recently, the Food and Drug Administration has published a list of 93 chemica
Externí odkaz:
https://doaj.org/article/ca162e0b983045f89a9d501e567b1be8
Autor:
Nicole R. L. Sparks, Lauren M. Walker, Steven R. Sera, Joseph V. Madrid, Michael Hanna, Edward C. Dominguez, Nicole I. zur Nieden
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2474 (2022)
Epidemiological studies suggest cigarette smoking as a probable environmental factor for a variety of congenital anomalies, including low bone mass, increased fracture risk and poor skeletal health. Human and animal in vitro models have confirmed hyp
Externí odkaz:
https://doaj.org/article/07c1209263284e1a89ffab36c48c4aac
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9904 (2022)
Exposure to cigarette smoke represents the largest source of preventable death and disease in the United States. This may be in part due to the nature of the delayed harmful effects as well as the lack of awareness of the scope of harm presented by t
Externí odkaz:
https://doaj.org/article/80361a41c01d47df8439ef7d48dec0ad
Autor:
Yen-Yu Yang, Ruthia Soh, Madeline Vera-Colón, Ming Huang, Nicole I. zur Nieden, Yinsheng Wang
Publikováno v:
Analytical Chemistry. 95:6879-6887
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101265- (2021)
Traditional methods of quantifying osteoblast calcification in culture require the use of calcium sensitive dyes, such as Arsenazo III or Alizarin Red S, which have been successfully used for decades to assess osteogenesis. Because these dyes elicit
Externí odkaz:
https://doaj.org/article/e740108dc4774e1ebaf6399b7fc76b10
Publikováno v:
Birth Defects Research. 114:1056-1074
Background: Diabetes, which is characterized by an increase in blood glucose concentration, is accompanied by low bone turnover, increased fracture risk, and the formation of embryonic skeletal malformations. Yet, there are few studies elucidating th
Autor:
Lauren Michelle Walker, Nicole R. L. Sparks, Veronica Puig-Sanvicens, Beatriz Rodrigues, Nicole I. zur Nieden
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8114 (2021)
To prevent congenital defects arising from maternal exposure, safety regulations require pre-market developmental toxicity screens for industrial chemicals and pharmaceuticals. Traditional embryotoxicity approaches depend heavily on the use of low-th
Externí odkaz:
https://doaj.org/article/367de607bd944661ae0c77700786c483
Publikováno v:
Nicotine & Tobacco Research. 24:1921-1926
Introduction Tobacco smoking has been implicated in an array of adverse health outcomes, including those that affect adult bone. However, little is known about the impact of tobacco products on developing bone tissue as it develops in the embryo. Aim
Autor:
Darcie L. McClelland Descalzo, Tiffany S. Satoorian, Lauren M. Walker, Nicole R.L. Sparks, Polina Y. Pulyanina, Nicole I. zur Nieden
Publikováno v:
Stem Cell Reports, Vol 7, Iss 1, Pp 55-68 (2016)
Embryonic stem cells (ESCs), which are derived from a peri-implantation embryo, are routinely cultured in medium containing diabetic glucose (Glc) concentrations. While pregnancy in women with pre-existing diabetes may result in small embryos, whethe
Externí odkaz:
https://doaj.org/article/155d41934c0443c89ac18925c8299cc8
Autor:
Lauren Walker, Laura Baumgartner, Kevin C. Keller, Julia Ast, Susanne Trettner, Nicole I. zur Nieden
Publikováno v:
Toxicology Reports, Vol 2, Iss C, Pp 165-174 (2015)
Many industrial chemicals and their respective by-products need to be comprehensively evaluated for toxicity using reliable and efficient assays. In terms of teratogenicity evaluations, the murine-based embryonic stem cell test (EST) offers a promisi
Externí odkaz:
https://doaj.org/article/8115a3c9f67749fa90a368ea3a43d558