Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nicole Hannemann"'
The Transcription Factor FRA-1/AP-1 Controls Lipocalin-2 Expression and Inflammation in Sepsis Model
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Sepsis is a life-threatening condition characterized by excessive inflammation in its early phase. This is followed by an aberrant resolution phase associated to a prolonged period of immune suppression that can ultimately lead to multiple organ dysf
Externí odkaz:
https://doaj.org/article/5bbf8f4c8f0b44a0907667d9b987ea8b
The Transcription Factor FRA-1/AP-1 Controls Lipocalin-2 Expression and Inflammation in Sepsis Model
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Sepsis is a life-threatening condition characterized by excessive inflammation in its early phase. This is followed by an aberrant resolution phase associated to a prolonged period of immune suppression that can ultimately lead to multiple organ dysf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9436fa90315e5a85965663c5fd6307c
https://doi.org/10.3389/fimmu.2021.701675
https://doi.org/10.3389/fimmu.2021.701675
Publikováno v:
Trends in immunology. 42(5)
Like other tissues, joints contain resident macrophages, and their diversity is only beginning to be characterized. Based on the highlights of recent studies, we discuss where current challenges lie and propose new avenues for future research in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60ce60d874f17e4c6bc54f244906e33f
https://pubmed.ncbi.nlm.nih.gov/33832864
https://pubmed.ncbi.nlm.nih.gov/33832864
Autor:
Jutta Jordan, Anne Schnelzer, Martin Eberhardt, Ulrike Schleicher, Arif B. Ekici, Georg Schett, Jürgen Rech, Aline Bozec, Christian Bogdan, Tobias Bäuerle, Steffen Uebe, Juan D. Cañete, Shan Cao, Nicole Hannemann, Daniel Eriksson, Andreas Ramming, Xiao-Xiang Chen, Julio Vera
Publikováno v:
The Journal of clinical investigation. 129(7)
The polarization of macrophages is regulated by transcription factors such as nuclear factor kappa B (NF-κB) and activator protein 1 (AP-1). In this manuscript, we delineated the role of the transcription factor Fos-related antigen 1 (Fra-1) during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b8e35db2a37c5926295de5548cc438
https://pubmed.ncbi.nlm.nih.gov/31053833
https://pubmed.ncbi.nlm.nih.gov/31053833
Autor:
Ulrike Schleicher, Nicole Hannemann, Georg Schett, Anne Schnelzer, Jürgen Rech, Aline Bozec, Tobias Bäuerle, Arif B. Ekici, S. Cao, Christian Bogdan, Jutta Jordan, Martin Eberhardt, Julio Vera, Steffen Uebe
Publikováno v:
Abstracts.
Career situation of first and presenting author Student for a master or a PhD. Introduction The activator protein (AP)-1 transcription factor family, especially its subfamily of FOS proteins (cFos, FosB, Fra-1 and Fra-2) are associated to the regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eabc854ec4f6d59c53ed0d350b18d5f9
https://doi.org/10.1136/annrheumdis-2018-ewrr2019.53
https://doi.org/10.1136/annrheumdis-2018-ewrr2019.53
Publikováno v:
Joint Bone Spine. 88:105091
Rheumatoid arthritis (RA) is a prototypic autoimmune disease that primarily affects joints. Clinical studies and animal models evidenced that mononuclear phagocytes including monocytes and macrophages are crucial to RA pathogenesis, contributing to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a0d62b0ae9b58e8b0861ddcf88adc2
https://doi.org/10.1016/j.jbspin.2020.105091
https://doi.org/10.1016/j.jbspin.2020.105091
Autor:
Cecilia Engdahl, Edina Sehic, Nicole Hannemann, Karin Gustafsson, Anna-Maria Liphardt, Georg Schett, Sara H Windahl, Aline Bozec
Publikováno v:
Bone. 131:115149
Arthritis induces bone loss by inflammation-mediated disturbance of bone homeostasis. On the other hand, pain and impaired locomotion are highly prevalent in arthritis and result in reduced general physical activity and less pronounced mechanical loa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec85e12924dbc4a6df57c8f9ec4ff6a
https://doi.org/10.1016/j.bone.2019.115149
https://doi.org/10.1016/j.bone.2019.115149
Autor:
Özge Uluçkan, Maria Jimenez, Neng-Yu Lin, Natacha Ipseiz, Yubin Luo, Bettina Grötsch, Erwin F. Wagner, Georg Schett, Nicole Hannemann, Aline Bozec
Publikováno v:
Molecular and Cellular Biology
Inflammatory responses require mobilization of innate immune cells from the bone marrow. The functionality of this process depends on the state of the bone marrow microenvironment. We therefore hypothesized that molecular changes in osteoblasts, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28604b6b2c795f2b81250cd268d9b49
https://pubmed.ncbi.nlm.nih.gov/30181393
https://pubmed.ncbi.nlm.nih.gov/30181393
Autor:
Bettina Herbort, Mireia Garcia, Kenia Ubieta, Nicole Hannemann, Louis Casteilla, Georg Schett, Martin Herrmann, Aline Bozec, Jean-Pierre David, Christian Jorgensen, Danièle Noël, Kay Schwabe, Michael Stock, Julia Luther
Publikováno v:
Arthritis & Rheumatology. 68:138-151
Objective To determine whether overexpression of the activator protein 1 (AP-1) transcription factor Fra-1 in adipose-derived stromal cells (ADSCs) is an effective treatment of collagenase-induced osteoarthritis (OA). Methods OA was induced by inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09b400a05c5609c2ad2317491f826bf1
https://doi.org/10.1002/art.39425
https://doi.org/10.1002/art.39425
Autor:
Stefan Wirtz, Luis Munos, Gerhard Krönke, Aline Bozec, Tobias Bäuerle, Georg Schett, Yubin Luo, Natacha Ipseiz, Guang-Liang Chen, Nicole Hannemann
Publikováno v:
Cell Metabolism. 22:886-894
SummaryThe effect of metabolic stress on the bone marrow microenvironment is poorly defined. We show that high-fat diet (HFD) decreased long-term Lin−Sca-1+c-Kit+ (LSK) stem cells and shifted lymphoid to myeloid cell differentiation. Bone marrow ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd577c0b60eb166d8ab76e4c6a19850
https://doi.org/10.1016/j.cmet.2015.08.020
https://doi.org/10.1016/j.cmet.2015.08.020