Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nicole Hanley"'
Autor:
Yosuke Hashimoto, Chris Greene, Nicole Hanley, Natalie Hudson, David Henshall, Kieron J. Sweeney, Donncha F. O’Brien, Matthew Campbell
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Claudin-5 is one of the most essential tight junction proteins at the blood-brain barrier. A single nucleotide polymorphism rs10314 is located in the 3’-untranslated region of claudin-5 and has been shown to be a risk factor for schizophre
Externí odkaz:
https://doaj.org/article/98b5ff94a6a24d43b835d870d78b8704
Autor:
Chris Greene, Nicole Hanley, Cristina R. Reschke, Avril Reddy, Maarja A. Mäe, Ruairi Connolly, Claire Behan, Eoin O’Keeffe, Isobel Bolger, Natalie Hudson, Conor Delaney, Michael A. Farrell, Donncha F. O’Brien, Jane Cryan, Francesca M. Brett, Alan Beausang, Christer Betsholtz, David C. Henshall, Colin P. Doherty, Matthew Campbell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The mechanisms underlying epilepsy development are not well understood. Here the authors show that loss of a key component of the so called blood-brain barrier drives seizures in mice and is also lost in humans with treatment resistant epilepsy
Externí odkaz:
https://doaj.org/article/4e4b16153a6148c99d2bb1956b4675ce
Publikováno v:
Fluids and Barriers of the CNS, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Tight junction proteins of the blood–brain barrier are vital for maintaining integrity of endothelial cells lining brain blood vessels. The presence of these protein complexes in the space between endothelial cells creates a dynamic, highl
Externí odkaz:
https://doaj.org/article/252e35118f6747f996a8206a8090c650
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Translational Psychiatry
Translational Psychiatry
Major psychiatric disorders affect 25% of the population. While genetic and environmental risk factors have been identified, the underlying pathophysiology of conditions, such as schizophrenia, bipolar disorder and major depression remains largely un
Autor:
Barbara Shapleigh, Susan Carpenter, Sergio Covarrubias, Michael T. McManus, Nicole Hanley, Elektra K. Robinson, Solomon Katzman, Nicholas Fong, Apple Cortez Vollmers
Publikováno v:
The Journal of biological chemistry, vol 292, iss 51
The Journal of Biological Chemistry
The Journal of Biological Chemistry
The innate immune system protects against infections by initiating an inducible inflammatory response. NF-κB is one of the critical transcription factors controlling this complex response, but some aspects of its regulation remain unclear. For examp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0a3e6e8ced37216a3de794cabbb169
https://escholarship.org/uc/item/7xr5v2p3
https://escholarship.org/uc/item/7xr5v2p3
Publikováno v:
American Journal of Gastroenterology. 113:S1312-S1313
Publikováno v:
Journal of clinical gastroenterology. 46(3)
Historical ambulatory pH monitoring systems for the evaluation of gastroesophageal reflux disease have been catheter based and uncomfortable for patients, commonly limiting both their diet and activities. Catheter-based studies have also been reporte
Publikováno v:
American Journal of Gastroenterology. 108:S309-S310
Publikováno v:
Gastroenterology. 142:S-839
Publikováno v:
Clinical Gastroenterology and Hepatology. 10:331