Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Nicole H. Hirsh"'
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Akademický článek
RB expression confers sensitivity to CDK4/6 inhibitor–mediated radiosensitization across breast cancer subtypes
Autor: Andrea M. Pesch, Nicole H. Hirsh, Anna R. Michmerhuizen, Kassidy M. Jungles, Kari Wilder-Romans, Benjamin C. Chandler, Meilan Liu, Lynn M. Lerner, Charles A. Nino, Connor Ward, Erin F. Cobain, Theodore S. Lawrence, Lori J. Pierce, James M. Rae, Corey W. Speers
Publikováno v: JCI Insight, Vol 7, Iss 3 (2022)
Standard radiation therapy (RT) does not reliably provide locoregional control for women with multinode-positive breast cancer and triple-negative breast cancer (TNBC). We hypothesized that CDK4/6 inhibition (CDK4/6i) would increase the radiosensitiv
Externí odkaz: https://doaj.org/article/a01908851a6948f19c0bebb697957f52
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5
Data from Short-term CDK4/6 Inhibition Radiosensitizes Estrogen Receptor–Positive Breast Cancers
Autor: Corey W. Speers, James M. Rae, Lori J. Pierce, José M. Larios, Christina L. Gersch, Meilan Liu, Kari Wilder-Romans, Marlie P. Androsiglio, Cassandra L. Ritter, Anna R. Michmerhuizen, Benjamin C. Chandler, Nicole H. Hirsh, Andrea M. Pesch
Purpose:Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have improved progression-free survival for metastatic, estrogen receptor–positive (ER+) breast cancers, but their role in the nonmetastatic setting remains unclear. We sought to understand th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352f4e1af5ba38fbb7d886201cb5ba6b
https://doi.org/10.1158/1078-0432.c.6529395.v1
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7
Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
Autor: Andrea M. Pesch, Benjamin C. Chandler, Anna R. Michmerhuizen, Hannah M. Carter, Nicole H. Hirsh, Kari Wilder-Romans, Meilan Liu, Tanner Ward, Cassandra L. Ritter, Charles A. Nino, Kassidy M. Jungles, Lori J. Pierce, James M. Rae, Corey W. Speers
Publikováno v: Cancer Res Commun
Patients with radioresistant breast cancers, including a large percentage of women with triple-negative breast cancer (TNBC), demonstrate limited response to radiation and increased locoregional recurrence; thus, strategies to increase the efficacy o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255573b8587c5d538ac7735fc0ea369d
https://europepmc.org/articles/PMC9648413/
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