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pro vyhledávání: '"Nicole Hübener"'
Autor:
Holger N. Lode, Doron Shabat, Ulrike Schröder, Kathrin M. Bernt, Wolf Wrasidlo, Nicole Hübener, Gerhard Gaedicke
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:557-560
Two 4'-propylcarbonoxy derivatives (2,3) of etoposide (1), a topoisomerase II inhibitor, were synthesized and evaluated as potential prodrugs for anticancer therapy. Their activation via hydrolysis mechanisms was determined as a function of pH in buf
Publikováno v:
Archives of microbiology. 179(1)
Chromate resistance inRalstonia metallidurans CH34 is based on chromate efflux catalyzed by ChrA efflux pumps. The bacterium harbors two chromate resistance determinants, the previously knownchr 1 on plasmid pMOL28 (geneschrI, chrB 1,chrA 1,chrC, chr