Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicole Grable"'
Autor:
Alexei Brooun, Ketan S. Gajiwala, Ya-Li Deng, Wei Liu, Ben Bolaños, Patrick Bingham, You-Ai He, Wade Diehl, Nicole Grable, Pei-Pei Kung, Scott Sutton, Karen A. Maegley, Xiu Yu, Al E. Stewart
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Polycomb repressive complex 2 (PRC2) mediates gene silencing through chromatin reorganization by methylation of histone H3 lysine 27 (H3K27). Here, the authors present crystal structures of the inhibitor-bound wild-type and a mutant form of PRC2.
Externí odkaz:
https://doaj.org/article/845df6d19e6c440e8657bbebe46e34a8
Autor:
JianHua Liu, Nicole Grable, Timothy J. Strelevitz, R. Scott Obach, Ciarán N. Cronin, Anthony Carlo
Publikováno v:
Protein Expression and Purification. 179:105769
Autor:
JianHua Liu, Anthony Carlo, Ciarán N. Cronin, Nicole Grable, Timothy J. Strelevitz, R. Scott Obach
Publikováno v:
Protein Expression and Purification. 177:105749
Human aldehyde oxidase (AOX) has emerged as a key enzyme activity for consideration in modern drug discovery. The enzyme catalyzes the oxidation of a wide variety of compounds, most notably azaheterocyclics that often form the building blocks of smal
Autor:
Pei-Pei Kung, Ya-Li Deng, Alexei Brooun, Xiu Yu, Wade Diehl, You-Ai He, Ketan S. Gajiwala, Ben Bolaños, Al E. Stewart, Wei Liu, Sutton Scott Channing, Patrick Bingham, Nicole Grable, Karen A. Maegley
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications
Nature Communications
Polycomb repressive complex 2 (PRC2) mediates gene silencing through chromatin reorganization by methylation of histone H3 lysine 27 (H3K27). Overexpression of the complex and point mutations in the individual subunits of PRC2 have been shown to cont