Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nicole Eilert"'
Autor:
Johann Moschner, Anna Chentsova, Nicole Eilert, Irene Rovardi, Philipp Heretsch, Athanassios Giannis
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2328-2335 (2013)
The chemical synthesis and biological evaluation of new cyclopamine analogs bearing exocyclic methylenes in different positions is described. Bis-exo-cyclopamine 6 was identified as a potent inhibitor of the Gli1-dependent luciferase expression in Sh
Externí odkaz:
https://doaj.org/article/edbb78dd43eb4ac7a7c811fcbdb1621e
Autor:
Philipp Heretsch, Irene Rovardi, Anna Chentsova, Athanassios Giannis, Johann Moschner, Nicole Eilert
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2328-2335 (2013)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
The chemical synthesis and biological evaluation of new cyclopamine analogs bearing exocyclic methylenes in different positions is described. Bis-exo-cyclopamine 6 was identified as a potent inhibitor of the Gli1-dependent luciferase expression in Sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bec50068ce884f15ebf8da162096bfe
https://doaj.org/article/edbb78dd43eb4ac7a7c811fcbdb1621e
https://doaj.org/article/edbb78dd43eb4ac7a7c811fcbdb1621e
Autor:
Katrin Seifert, Stephan Rigol, Elke Wandel, Anita Büttner, Nicole Eilert, Athanassios Giannis
Publikováno v:
Bioorganicmedicinal chemistry. 20(21)
Here, we describe the synthesis, SAR studies as well as biological investigations of the known Hedgehog signaling agonist SAG and a small library of its analogues. The SAG and its derivatives were analyzed for their potency to activate the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f77f7af057c8af55e789bd9b1e3b8bd
https://pubmed.ncbi.nlm.nih.gov/22985958
https://pubmed.ncbi.nlm.nih.gov/22985958