Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicole E. Lima"'
Publikováno v:
Poster Presentations.
Background Major challenges in the management of infectious diseases include treatment failure due to antimicrobial resistance (AMR) and the lack of a reliable test of cure (TOC). Whilst culture is a trusted method it is slow, and with the widespread
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45168fb99eaaec6c9244eb376bbcfb51
https://doi.org/10.1136/sextrans-2019-sti.269
https://doi.org/10.1136/sextrans-2019-sti.269
EzyAmp signal amplification cascade enables isothermal detection of nucleic acid and protein targets
Autor:
Alison V. Todd, Evelyn Meiria Linardy, Nicole E. Lima, Elisa Mokany, Tina Lonergan, Simon Erskine
Publikováno v:
Biosensors and Bioelectronics. 75:59-66
Advancements in molecular biology have improved the ability to characterize disease-related nucleic acids and proteins. Recently, there has been an increasing desire for tests that can be performed outside of centralised laboratories. This study desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146832b15446d627ae9c2b3339be179b
Publikováno v:
Biosensors and Bioelectronics. 70:330-337
We have created molecular switches that consist of nucleic-acid cleaving DNAzymes which are temporarily inactivated by hybridization with blocking oligonucleotides. The unique design of the switches offers significant advantages over existing methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3ef4b84dc642e9c34c4569cbf875c4
https://doi.org/10.1016/j.bios.2015.03.057
https://doi.org/10.1016/j.bios.2015.03.057
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170087 (2017)
PLoS ONE
PLoS ONE
Background Whilst qPCR provides an extremely powerful tool for genetic analysis, some applications such as multiplexing variant alleles (eg SNPs, point mutations or deletions), remain challenging using current primer/probe systems. The novel design f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330d6a831ba856cc0256de2a84e06806
http://europepmc.org/articles/PMC5256879?pdf=render
http://europepmc.org/articles/PMC5256879?pdf=render
Publikováno v:
Analytical Chemistry. 86:9106-9113
Diagnostic tests performed in the field or at the site of patient care would benefit from using a combination of inexpensive, stable chemical reagents and simple instrumentation. Here, we have developed a universal "DNA-only Cascade" (DoC) to quantit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c87e7bf72d3b90624ea4d494ed55b2
https://doi.org/10.1021/ac501811r
https://doi.org/10.1021/ac501811r
Publikováno v:
Environmental Microbiology Reports. 4:89-96
Summary We demonstrate that the exhaled breath condensate, or ‘blow’, from marine mammals can be used to examine respiratory associated microbial communities using non-invasive sampling methods. Blow samples from two species of bottlenose dolphin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03499ce3ccbb8c92fb7f0900816947ef
https://doi.org/10.1111/j.1758-2229.2011.00306.x
https://doi.org/10.1111/j.1758-2229.2011.00306.x
Autor:
Katrien Vermeiren, Erwin Sablon, Bart Claes, Ina Vandenbroucke, Geert Maertens, Alison V. Todd, Samantha Walker, Nicole E. Lima, Geneviève Vandercruyssen, Elisa Mokany, Lit Yeen Tan, Pascale Holemans, Evelien Rondelez, Inky De Baere
Publikováno v:
Cancer Research. 74:1502-1502
Introduction The MAPK/ERK pathway is a complex signaling cascade involved in many cancer types. KRAS and BRAF gene mutations are present in a number of cancers, including colon, lung and pancreas, and identification of mutations in these genes is of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8991ca4b0f6b75e50d88e710b31918f
https://doi.org/10.1158/1538-7445.am2014-1502
https://doi.org/10.1158/1538-7445.am2014-1502