Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicole E. Friend"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Strategies to separately manufacture arterial-scale tissue engineered vascular grafts and microvascular networks have been well-established, but efforts to bridge these two length scales to create hierarchical vasculature capable of supporti
Externí odkaz:
https://doaj.org/article/435809aa57a142cda585c1928680dc17
Autor:
Alexander Ky, Atticus J. McCoy, Carmen G. Flesher, Nicole E. Friend, Jie Li, Kore Akinleye, Christopher Patsalis, Carey N. Lumeng, Andrew J. Putnam, Robert W. O’Rourke
Publikováno v:
Adipocyte, Vol 12, Iss 1 (2023)
ABSTRACTAlterations of the extracellular matrix contribute to adipose tissue dysfunction in metabolic disease. We studied the role of matrix density in regulating human adipocyte phenotype in a tunable hydrogel culture system. Lipid accumulation was
Externí odkaz:
https://doaj.org/article/849bf78638d543b0b0b52a41d2e819ae
Publikováno v:
Trends in Biotechnology.
Publikováno v:
Tissue Eng Part B Rev
Inadequate vascularization of engineered tissue constructs is a main challenge in developing a clinically impactful therapy for large, complex, and recalcitrant bone defects. It is well established that bone and blood vessels form concomitantly durin
Publikováno v:
Biomaterials. 295:122050
Autor:
Xiaowei Hong, Andrew J. Putnam, Nicole E. Friend, Ana Y. Rioja, Jan P. Stegemann, Cheri X. Deng, Yen Peng Kong, Julia C. Habif, Jeffrey A. Beamish, Jonathan R. Bezenah
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Revascularization of ischemic tissues is a major barrier to restoring tissue function in many pathologies. Delivery of pro-angiogenic factors has shown some benefit, but it is difficult to recapitulate the complex set of factors required to form stab
Publikováno v:
Biotechnology and Bioengineering. 116:415-426
Forming functional blood vessel networks is a major clinical challenge in the fields of tissue engineering and therapeutic angiogenesis. Cell-based strategies to promote neovascularization have been widely explored, but cell sourcing remains a signif