Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nicole E. Burma"'
Autor:
Charlie H. T. Kwok, Erika K. Harding, Nicole E. Burma, Tamara Markovic, Nicolas Massaly, Nynke J. van den Hoogen, Sierra Stokes-Heck, Eder Gambeta, Kristina Komarek, Hye Jean Yoon, Kathleen E. Navis, Brendan B. McAllister, Julia Canet-Pons, Churmy Fan, Rebecca Dalgarno, Evgueni Gorobets, James W. Papatzimas, Zizhen Zhang, Yuta Kohro, Connor L. Anderson, Roger J. Thompson, Darren J. Derksen, Jose A. Morón, Gerald W. Zamponi, Tuan Trang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Opioid withdrawal is a liability of chronic opioid use and misuse, impacting people who use prescription or illicit opioids. Hyperactive autonomic output underlies many of the aversive withdrawal symptoms that make it difficult to discontinu
Externí odkaz:
https://doaj.org/article/d65c6d8ddef244efbd66f10b378d8cc2
Autor:
Jo Anne Stratton, Alexandra Holmes, Nicole L. Rosin, Sarthak Sinha, Mohit Vohra, Nicole E. Burma, Tuan Trang, Rajiv Midha, Jeff Biernaskie
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2561-2572.e6 (2018)
Summary: Pro-regenerative macrophages are well known for their role in promoting tissue repair; however, their specific roles in promoting regeneration of the injured nerve are not well defined. Specifically, how macrophages interact with Schwann cel
Externí odkaz:
https://doaj.org/article/e2373eec6f404440b6378660a2bc5ed5
Publikováno v:
Skin therapy letter. 27(1)
The pathogenesis of acne is multifactorial and involves inflammation, bacterial dysbiosis, and androgen stimulation. Existing systemic therapies target hormonal pathways to mitigate acne lesions; however, their use is limited to the female population
Autor:
Anna M.W. Taylor, Lindsay M. Lueptow, F. Ivy Carroll, Inés Ibarra-Lecue, Tuan Trang, Joshua K. Hakimian, Kristina Komarek, Frances M. Leslie, Anne M. Andrews, Amie L. Severino, Shiwei Liu, Sarah Pickens, Caroline E. Bass, Hongyan Yang, Christopher Cook, Wendy Walwyn, Nicole E. Burma, Catherine M. Cahill, Christopher J. Evans, Lihua Xue, Mary C. Olmstead
Publikováno v:
The Journal of Neuroscience. 39:4162-4178
Pain is a multidimensional experience and negative affect, or how much the pain is “bothersome”, significantly impacts the sufferers' quality of life. It is well established that the κ opioid system contributes to depressive and dysphoric states
Autor:
Tuan Trang, Céline Jean-Xavier, Simon A. Sharples, Joanna Borowska-Fielding, Shane E. A. Eaton, Ying Zhang, Nicole E. Burma, Charlie H.T. Kwok, Patrick J. Whelan, Glen B. Baker
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-23 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-23 (2020)
Dopamine is well known to regulate movement through the differential control of direct and indirect pathways in the striatum that express D1 and D2 receptors respectively. The spinal cord also expresses all dopamine receptors however; how the specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6a70c1d76fa1e5ad95a164839e3852
https://hdl.handle.net/10023/20730
https://hdl.handle.net/10023/20730
Publikováno v:
Pain Management. 7:455-459
Autor:
Nicole E. Burma, Roger J. Thompson, Tuan Trang, Heather Leduc-Pessah, Nicholas L. Weilinger, Churmy Y. Fan
Publikováno v:
The Journal of Neuroscience. 37:10154-10172
Tolerance to the analgesic effects of opioids is a major problem in chronic pain management. Microglia are implicated in opioid tolerance, but the core mechanisms regulating their response to opioids remain obscure. By selectively ablating microglia
Publikováno v:
Channels. 11:487-494
Opioids are among the most powerful analgesics for managing pain, yet their repeated use can lead to the development of severe adverse effects. In a recent study, we identified the microglial pannexin-1 channel (Panx1) as a critical substrate for opi