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pro vyhledávání: '"Nicole E Douglass"'
Autor:
Amita Datta-Mannan, Selina Estwick, Chen Zhou, Hiuwan Choi, Nicole E. Douglass, Derrick R. Witcher, Jirong Lu, Catherine Beidler, Rohn Millican
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Many therapeutic monoclonal antibodies (mAbs) were initially developed for intravenous (IV) administration. As a means to improve mAb drug-ability and the patient experience, subcutaneous (SC) administration is an increasingly important delivery rout
Externí odkaz:
https://doaj.org/article/58c5f4e8c8a14a51b74643d2b367cca2
Autor:
Rohn Lee Millican, Chen Zhou, Catherine Brautigam Beidler, Nicole E Douglass, Jirong Lu, Derrick R. Witcher, Amita Datta-Mannan, Selina Estwick, Hiuwan Choi
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Many therapeutic monoclonal antibodies (mAbs) were initially developed for intravenous (IV) administration. As a means to improve mAb drug-ability and the patient experience, subcutaneous (SC) administration is an increasingly important delivery rout
Autor:
Nicole E Douglass, Zhaoyan Y. Jin, Anthony T. Murphy, Jeffrey S. Boyles, Bernice Ellis, Amita Datta-Mannan, Fariba Norouziyan-Cooper, Amber Peariso, Lihua Huang, Derrick R. Witcher
Publikováno v:
Biotechnology Journal. 14:1800007
There is a rapidly growing reinvigoration of the investigation of small proteins, cyclic peptides, and mAb derived domains as biotherapies. The drugability of these structures are challenged by fast peripheral clearance properties that can reduce the