Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicole Duriga"'
Autor:
Chuenlei Parng, Boris Gorovits, Rob Webster, Teresa M Caiazzo, Nicole Duriga, Debra D. Pittman, Michael W. Bolt, Alison Joyce, Beth A. Leary, Victoria Markiewicz, Jianqing Chen, Lisa Dyleski
Publikováno v:
Journal of Pharmaceutical Sciences. 106:2136-2143
FXaI16L is a recombinant human FXa variant which is currently being evaluated in the clinic for treating intracerebral hemorrhage. The aim of our studies is to investigate overall pharmacokinetics, pharmacodynamics, and distribution of FXaI16L in pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa0aa25dfea0ee3ee0f2b82522f66191
https://doi.org/10.1016/j.xphs.2017.03.035
https://doi.org/10.1016/j.xphs.2017.03.035
Autor:
Mauricio Leal, Nicole Duriga, Judy Lucas, Franklin Spriggs, Eugene P. Kadar, Brian Rago, Jo-Ann Wentland, Quazi Shakey, Xiaogang Han, Wei Song, Jim McNally, Leslie G. Lorello, Yanhua Zhang, Puja Sapra
Publikováno v:
Bioconjugate chemistry. 26(11)
The pharmacokinetics of an antibody (huA1)-drug (auristatin microtubule disrupting MMAF) conjugate, targeting 5T4-expressing cells, were characterized during the discovery and development phases in female nu/nu mice and cynomolgus monkeys after a sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25789a1784a3ef9e7205d6f1b0ec4a0
https://pubmed.ncbi.nlm.nih.gov/26180901
https://pubmed.ncbi.nlm.nih.gov/26180901
Publikováno v:
Bioanalysis. 6(8)
Background: Matrix effects pose a constant challenge in developing robust ligand-binding assays to be validated for use in nonclinical and clinical study support. When notable matrix effects of any kind are present, it can render an otherwise sound m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8c2bcc04c07763ab3ba07b38c4b7f5
https://pubmed.ncbi.nlm.nih.gov/24830893
https://pubmed.ncbi.nlm.nih.gov/24830893
Autor:
Mauricio Leal, JoAnn Wentland, Xiaogang Han, Yanhua Zhang, Brian Rago, Nicole Duriga, Franklin Spriggs, Eugene Kadar, Wei Song, James McNally, Quazi Shakey, Leslie Lorello, Judy Lucas, Puja Sapra
Publikováno v:
Bioconjugate Chemistry; Nov2015, Vol. 26 Issue 11, p2223-2232, 10p