Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nicole Duerrschmidt"'
Autor:
Silke Krabbes-Graube, Andreas Boldt, Stefan Dhein, Anja Reutemann, Friedrich-Wilhelm Mohr, B Pfannmüller, Nicole Duerrschmidt
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 61:066-073
Background The authors wanted to investigate whether the remodeling process in AF regarding gap junction proteins, collagen I, and amyloid may be gender dependent in humans. Methods In total, 123 patients with sinus rhythm (SR, n = 41) or atrial fibr
Autor:
Stefan Dhein, Alice Wermke, Anja Hagen, Nicole Duerrschmidt, Christiane Gaertner, Friedrich-Wilhelm Mohr, Marcin Nowicki, Katharina Spanel-Borowski, Holger Stepan
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 385:621-632
Since previous in vitro experiments revealed that nicotine can impair endothelial intercellular communication via the downregulation of connexin43 (Cx43), we wanted to find out which nicotinic acetylcholine receptors are involved in the molecular mec
Publikováno v:
The Journal of Physiology. 576:557-567
The flowing blood generates shear stress at the endothelial cell surface. In endothelial cells, NAD(P)H oxidase complexes have been identified as major sources of superoxide anion (·O2−) formation. In this study, we analysed the effect of laminar
Autor:
Katharina Spanel-Borowski, Verona Blumenauer, Fayez A. Hmeidan, Olga Zabirnyk, Jürgen Borlak, Marcin Nowicki, Albert M. Ricken, Nicole Duerrschmidt
Publikováno v:
Endocrinology. 147:3851-3860
The LOX-1 receptor, identified on endothelial cells, mediates the uptake of oxidized low-density lipoprotein (oxLDL). The oxLDL-dependent LOX-1 activation causes endothelial cell apoptosis. We here investigated the presence of LOX-1 in granulosa cell
Autor:
Juergen Holtz, Henning Morawietz, Tatsuya Sawamura, Bernd Niemann, Nicole Duerrschmidt, Jan Galle
Publikováno v:
Biochemical and Biophysical Research Communications. 284:961-965
In this study, we analyzed the effect of endothelin-1 (ET-1) on expression of the lectin-like oxidized low-density lipoprotein (oxLDL) receptor-1 LOX-1 and on oxLDL uptake in primary cultures of human umbilical vein endothelial cells (HUVEC). LOX-1 m
Autor:
Tatsuya Sawamura, Bernd Niemann, Juergen Holtz, Henning Morawietz, Uwe Rueckschloss, Nicole Duerrschmidt, Jan Galle, Kavous Hakim, Hans-Reinhard Zerkowski
Publikováno v:
Circulation. 100:899-902
Background —Oxidatively modified LDL (oxLDL) plays an important role in the development of atherosclerosis. OxLDL effects, eg, foam cell formation, are mediated in part by the classic scavenger receptor, whereas other effects may involve the recent
Autor:
Friedrich-Wilhelm Mohr, Stefan Dhein, A Hagen, K Spanel-Borowski, Nicole Duerrschmidt, M Nowicki
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 60
Autor:
Henning Morawietz, Claudia Goettsch, Andreas H. Wagner, Coy Brunssen, Claudia Haschke, Melanie Brux, Nicole Duerrschmidt, Stefan R. Bornstein, Gregor Muller, Winfried Goettsch
Publikováno v:
Basic research in cardiology. 106(4)
The main sources of oxidative stress in the vessel wall are nicotine adenine dinucleotide phosphate (NADPH) oxidase (Nox) complexes. The endothelium mainly expresses the Nox4-containing complex; however, the mechanism by which shear stress in endothe
Autor:
A. Scholl, Stefan Dhein, J. S. Schulte, Friedrich-Wilhelm Mohr, Diana Rojas-Gomez, B. Pfannmüller, Jacques-Antoine Haefliger, N. Doll, A. Scheffler, A. Boldt, Nicole Duerrschmidt
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 377(2)
We wanted to elucidate whether extracellular calcium may regulate the expression of the cardiac gap-junction proteins connexin 40 and connexin43. In the free wall of the left atria of 126 cardiac surgery patients with either sinus rhythm (SR) or chro
Autor:
Friedrich-Wilhelm Mohr, Sven Lehmann, S. Krabbes, Andreas Boldt, B Pfannmüller, Stefan Dhein, Nico Doll, Nicole Duerrschmidt
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 55