Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicole Dudley-Rucker"'
Autor:
Jessie Zhang, Nicole Dudley-Rucker, Jan R. Crowley, Elvira Lopez-Perez, Marc Issandou, Jean E. Schaffer, Daniel S. Ory
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 2, Pp 223-231 (2004)
Recently, a new class of lipid-lowering agents has been described that upregulate LDL receptor (LDLr) activity. These agents are proposed to activate sterol-regulated gene expression through binding to the sterol regulatory element binding protein (S
Externí odkaz:
https://doaj.org/article/332d974bf5394121a4534479f154607b
Autor:
Brett N. Olsen, Sarah Jinn, Jean E. Schaffer, Rohini Sidhu, Aileen Ren, Nicole Dudley-Rucker, Hideji Fujiwara, Katrina A. Brandis, Hui Jiang, Anita Chacko, Sarah E. Gale, Daniel S. Ory
Publikováno v:
Cell Metabolism. 21(6):855-867
SummaryCholesterol is required for the growth and viability of mammalian cells and is an obligate precursor for steroid hormone synthesis. Using a loss-of-function screen for mutants with defects in intracellular cholesterol trafficking, a Chinese ha
Autor:
Aileen Ren, Nicole Dudley-Rucker, Katrina A. Brandis, Hui Jiang, Anna Goldberg, Rohini Sidhu, Sarah Jinn, Daniel S. Ory, Jean E. Schaffer, Sarah E. Gale, Stephen J. Langmade
Publikováno v:
Journal of Biological Chemistry. 288:35703-35713
Mobilization of plasma membrane (PM) cholesterol to the endoplasmic reticulum is essential for cellular cholesterol homeostasis. The mechanisms regulating this retrograde, intermembrane cholesterol transfer are not well understood. Because mutant cel
Autor:
Daniel S. Ory, Elvira Lopez-Perez, Jan R. Crowley, Jessie Zhang, Nicole Dudley-Rucker, Marc Issandou, Jean E. Schaffer
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 2, Pp 223-231 (2004)
Recently, a new class of lipid-lowering agents has been described that upregulate LDL receptor (LDLr) activity. These agents are proposed to activate sterol-regulated gene expression through binding to the sterol regulatory element binding protein (S
Autor:
Andrey Frolov, Nicole Dudley-Rucker, Jean E. Schaffer, Jan R. Crowley, Sarah E. Zielinski, Daniel S. Ory
Publikováno v:
Journal of Biological Chemistry. 278:25517-25525
Mutations in the Niemann-Pick disease genes cause lysosomal cholesterol accumulation and impaired low density lipoprotein (LDL) cholesterol esterification. These findings have been attributed to a block in cholesterol movement from lysosomes to the s
Autor:
E. Dale Abel, Arash Mohajer, Mitchell A. Lazar, Christophe Graveleau, Vlad G. Zaha, Claire M. Steppan, Ronadip R. Banerjee, Michael W. Rajala, Philipp E. Scherer, Nicole Dudley-Rucker, Rexford S. Ahima
Publikováno v:
The Journal of biological chemistry. 280(36)
The adipocytokine resistin impairs glucose tolerance and insulin sensitivity in rodents. Here, we examined the effect of resistin on glucose uptake in isolated adult mouse cardiomyocytes. Murine resistin reduced insulin-stimulated glucose uptake, est