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pro vyhledávání: '"Nicole Dieteren"'
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 307:121-129
The Luria-Delbruck fluctuation analysis provides a method to estimate mutation rates and is commonly applied in somatic cell genetics and in cancer biology. We developed an assay for a Luria-Delbruck fluctuation analysis using the mouse lymphoma cell
Autor:
Nicole Dieteren, David Arscott, Jacques A.E. Benen, Cees Veeger, Arie de Kok, Willem J. H. van Berkel, Charles H. Williams
Publikováno v:
European Journal of Biochemistry. 207:487-497
Three amino acid residues in the active site of lipoamide dehydrogenase from Azotobacter vinelandii were replaced with other residues. His450, the active-site base, was replaced with Ser, Tyr or Phe. Pro451, from X-ray analysis found to be in cis con
Publikováno v:
Carcinogenesis. 13(12)
Ultraviolet irradiation triggers a response in mammalian cells known as the UV response. Part of the UV response forms the enhanced synthesis of various extracellular proteins able to transmit the response to non-irradiated cells. Because several can