The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: In vitro and in vivo studies

Autor: Catalina Carrasco-Pozo, Kah Ni Tan, Marjorie Reyes-Farias, Nicole De La Jara, Shyuan Thieu Ngo, Diego Fernando Garcia-Diaz, Paola Llanos, Maria Jose Cires, Karin Borges

Publikováno v: Redox Biology, Vol 9, Iss C, Pp 229-243 (2016)

Studying rats fed high cholesterol diet and a pancreatic β-cell line (Min6), we aimed to determine the mechanisms by which quercetin protects against cholesterol-induced pancreatic β-cell dysfunction and impairments in glycemic control. Quercetin p

Externí odkaz: https://doaj.org/article/54dfde67e3df45fbbe9ce7e9b3fe4725

Quercetin prevents diastolic dysfunction induced by a high-cholesterol diet: role of oxidative stress and bioenergetics in hyperglycemic rats

Autor: Juan Pedro Peña, Rodrigo L. Castillo, Marjorie Reyes-Farias, Emilio A. Herrera, Catalina Carrasco-Pozo, Nicole de la Jara, Alejandro González-Candia

Publikováno v: Oxidative Medicine And Cellular Longevity
Artículos CONICYT
CONICYT Chile
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Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)

Alterations in cardiac energy metabolism play a key role in the pathogenesis of diabetic cardiomyopathy. Hypercholesterolemia associated with bioenergetic impairment and oxidative stress has not been well characterized in the cardiac function under g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634652fe93e1eeee19c745d2123c29d5

Quercetin Prevents Diastolic Dysfunction Induced by a High-Cholesterol Diet: Role of Oxidative Stress and Bioenergetics in Hyperglycemic Rats.

Autor: Castillo, Rodrigo L., Herrera, Emilio A., Gonzalez-Candia, Alejandro, Reyes-Farias, Marjorie, de la Jara, Nicole, Peña, Juan Pedro, Carrasco-Pozo, Catalina

Publikováno v: Oxidative Medicine & Cellular Longevity; 1/11/2018, p1-14, 14p