Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nicole D Armstrong"'
Autor:
Nicole D Armstrong, Marguerite R Irvin, William E Haley, Marcela D Blinka, Debora Kamin Mukaz, Amit Patki, Sue Rutherford Siegel, Idan Shalev, Peter Durda, Rasika A Mathias, Jeremy D Walston, David L Roth
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0268689 (2022)
Telomere length (TL) is widely studied as a possible biomarker for stress-related cellular aging and decreased longevity. There have been conflicting findings about the relationship between family caregiving stress and TL. Several initial cross-secti
Externí odkaz:
https://doaj.org/article/3e5c8164c2974252bdcca6b8e144ba10
Autor:
Alana C. Jones, Amit Patki, Vinodh Srinivasasainagendra, Bertha A. Hidalgo, Hemant K. Tiwari, Nita A. Limdi, Nicole D. Armstrong, Ninad S. Chaudhary, Bré Minniefield, Devin Absher, Donna K. Arnett, Leslie A. Lange, Ethan M. Lange, Bessie A. Young, Clarissa J. Diamantidis, Stephen S. Rich, Josyf C. Mychaleckyj, Jerome I. Rotter, Kent D. Taylor, Holly J. Kramer, Russell P. Tracy, Peter Durda, Silva Kasela, Tuuli Lappalinen, Yongmei Liu, W. Craig Johnson, David J. Van Den Berg, Nora Franceschini, Simin Liu, Charles P. Mouton, Parveen Bhatti, Steve Horvath, Eric A. Whitsel, Marguerite R. Irvin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Chronic kidney disease (CKD) impacts about 1 in 7 adults in the United States, but African Americans (AAs) carry a disproportionately higher burden of disease. Epigenetic modifications, such as DNA methylation at cytosine-phosphate-guanine (
Externí odkaz:
https://doaj.org/article/12deb3d0ae334de99921176e9c1f291a
Autor:
Nicole D. Armstrong, Amit Patki, Vinodh Srinivasasainagendra, Tian Ge, Leslie A. Lange, Leah Kottyan, Bahram Namjou, Amy S. Shah, Laura J. Rasmussen-Torvik, Gail P. Jarvik, James B. Meigs, Elizabeth W. Karlson, Nita A. Limdi, Marguerite R. Irvin, Hemant K. Tiwari
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Type 2 diabetes (T2D) is caused by both genetic and environmental factors and is associated with an increased risk of cardiorenal complications and mortality. Though disproportionately affected by the condition, African Americans (AA) are la
Externí odkaz:
https://doaj.org/article/d5034e28612d4f249c9d2e4426faf605
Autor:
Catharine A. Couch, Zsuzsanna Ament, Amit Patki, Naruchorn Kijpaisalratana, Varun Bhave, Alana C. Jones, Nicole D. Armstrong, Mary Cushman, W. Taylor Kimberly, M. Ryan Irvin
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Sex disparities exist in cardiometabolic diseases. Metabolomic profiling offers insight into disease mechanisms, as the metabolome is influenced by environmental and genetic factors. We identified metabolites associated with sex and determ
Externí odkaz:
https://doaj.org/article/7577f41ff38d48daa218931369b3cbb2
Autor:
Chad M. Aldridge, Nicole D. Armstrong, N. Abimbola Sunmonu, Christopher Becker, Deepak Palakshappa, Arne G. Lindgren, Annie Pedersen, Tara M. Stanne, Christina Jern, Jane Maguire, Fang-Chi Hsu, Keith L. Keene, Michele Sale, Marguerite R. Irvin, Bradford B. Worrall
Publikováno v:
Frontiers in Stroke, Vol 3 (2024)
IntroductionStroke is a leading cause of death and disability worldwide. Recurrent strokes are seven times more lethal than initial ones, with 54% leading to long-term disability. Substantial recurrent stroke risk disparities exist among ancestral gr
Externí odkaz:
https://doaj.org/article/bbb0c6c75d894b5a8514195db40f0dbe
Autor:
Nicole D. Armstrong, Vinodh Srinivasasainagendra, Farah Ammous, Themistocles L. Assimes, Amber L. Beitelshees, Jennifer Brody, Brian E. Cade, Yii-Der Ida Chen, Han Chen, Paul S. de Vries, James S. Floyd, Nora Franceschini, Xiuqing Guo, Jacklyn N. Hellwege, John S. House, Chii-Min Hwu, Sharon L. R. Kardia, Ethan M. Lange, Leslie A. Lange, Caitrin W. McDonough, May E. Montasser, Jeffrey R. O’Connell, Megan M. Shuey, Xiao Sun, Rikki M. Tanner, Zhe Wang, Wei Zhao, April P. Carson, Todd L. Edwards, Tanika N. Kelly, Eimear E. Kenny, Charles Kooperberg, Ruth J. F. Loos, Alanna C. Morrison, Alison Motsinger-Reif, Bruce M. Psaty, Dabeeru C. Rao, Susan Redline, Stephen S. Rich, Jerome I. Rotter, Jennifer A. Smith, Albert V. Smith, Marguerite R. Irvin, Donna K. Arnett
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Apparent treatment-resistant hypertension (aTRH) is characterized by the use of four or more antihypertensive (AHT) classes to achieve blood pressure (BP) control. In the current study, we conducted single-variant and gene-based analyse
Externí odkaz:
https://doaj.org/article/7b206fd782484f169fb7415ed4c3d533
Autor:
Frederik Denorme, Nicole D. Armstrong, Michelle L. Stoller, Irina Portier, Emilia A. Tugolukova, Rikki M. Tanner, Emilie Montenont, Seema Bhatlekar, Mark Cody, John L. Rustad, Abigail Ajanel, Neal D. Tolley, Darian C. Murray, Julie L. Boyle, Marvin T. Nieman, Steven E. McKenzie, Christian Con Yost, Leslie A. Lange, Mary Cushman, Marguerite R. Irvin, Paul F. Bray, Robert A. Campbell
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
Protease-activated receptor 4 (PAR4) (gene F2RL3) harbors a functional dimorphism, rs773902 A/G (encoding Thr120/Ala120, respectively) and is associated with greater platelet aggregation. The A allele frequency is more common in Black individuals, an
Externí odkaz:
https://doaj.org/article/d092af6b93764c9897fa3db88dadf434
Autor:
Tian Ge, Marguerite R. Irvin, Amit Patki, Vinodh Srinivasasainagendra, Yen-Feng Lin, Hemant K. Tiwari, Nicole D. Armstrong, Barbara Benoit, Chia-Yen Chen, Karmel W. Choi, James J. Cimino, Brittney H. Davis, Ozan Dikilitas, Bethany Etheridge, Yen-Chen Anne Feng, Vivian Gainer, Hailiang Huang, Gail P. Jarvik, Christopher Kachulis, Eimear E. Kenny, Atlas Khan, Krzysztof Kiryluk, Leah Kottyan, Iftikhar J. Kullo, Christoph Lange, Niall Lennon, Aaron Leong, Edyta Malolepsza, Ayme D. Miles, Shawn Murphy, Bahram Namjou, Renuka Narayan, Mark J. O’Connor, Jennifer A. Pacheco, Emma Perez, Laura J. Rasmussen-Torvik, Elisabeth A. Rosenthal, Daniel Schaid, Maria Stamou, Miriam S. Udler, Wei-Qi Wei, Scott T. Weiss, Maggie C. Y. Ng, Jordan W. Smoller, Matthew S. Lebo, James B. Meigs, Nita A. Limdi, Elizabeth W. Karlson
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic and environmental risk factors that disproportionately afflicts communities of color. Leveraging existing large-scale genome-wide association studies (GWAS), poly
Externí odkaz:
https://doaj.org/article/e049f828882147afa27dd2a692f0bc18
Autor:
Ninad S. Chaudhary, Nicole D. Armstrong, Bertha A. Hidalgo, Orlando M. Gutiérrez, Jacklyn N. Hellwege, Nita A. Limdi, Richard J. Reynolds, Suzanne E. Judd, Girish N. Nadkarni, Leslie Lange, Cheryl A. Winkler, Jeffrey B. Kopp, Donna K. Arnett, Hemant K. Tiwari, Marguerite R. Irvin
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundSome but not all African-Americans (AA) who carry APOL1 nephropathy risk variants (APOL1) develop kidney failure (end-stage kidney disease, ESKD). To identify genetic modifiers, we assessed gene–gene interactions in a large prospective co
Externí odkaz:
https://doaj.org/article/ea48565d903540c6ad32bf9b1b933bd3
Autor:
Vibhu Parcha, Marguerite R. Irvin, Leslie A. Lange, Nicole D. Armstrong, Akhil Pampana, Mariah Meyer, Suzanne E. Judd, Garima Arora, Pankaj Arora
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 12 (2022)
Background Corin enzyme contributes to the processing of inactive natriuretic peptides to bioactive hormones. In Black individuals, Corin gene variants (rs111253292 [Q568P] and rs75770792 [T555I]) have been previously reported to have a modest associ
Externí odkaz:
https://doaj.org/article/5a2eb53c5f034d03894f45f43d4a4736