Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicole Cuerdon"'
Autor:
Wassim Elyaman, Samia J. Khoury, Elizabeth W. Karlson, Joseph M. Replogle, Deepak A. Rao, Gyan Srivastava, Maria Cimpean, Allison McHenry, Michael B. Brenner, Michael Frangieh, Towfique Raj, William Orent, Ribal Bassil, Charles C. White, Philip L. De Jager, Lori B. Chibnik, Nicole Cuerdon, Hans-Ulrich Klein, Elizabeth M. Bradshaw
Publikováno v:
Human Molecular Genetics. 25:404-417
Notch signaling has recently emerged as an important regulator of immune responses in autoimmune diseases. The recombination signal-binding protein for immunoglobulin kappa J region (RBPJ) is a transcriptional repressor, but converts into a transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9031dc55870b1a98c391010731827e
https://doi.org/10.1093/hmg/ddv474
https://doi.org/10.1093/hmg/ddv474
Autor:
Kruti R. Patel, Nicole Cuerdon, Phoebe A. Winn, Katie J. Ryan, Michael Frangieh, Elizabeth M. Bradshaw, David A. Bennett, Philip L. De Jager, Belinda J. Kaskow, Charles C. White, Joseph M. Replogle, Allison McHenry, Wassim Elyaman, Marta Olah, Justin D. Boyd, Jaime Imitola, Gail Chan, Jishu Xu, Maria Cimpean
Publikováno v:
Science translational medicine. 9(421)
Microglia are emerging as a key cell type in neurodegenerative diseases, yet human microglia are challenging to study in vitro, especially in the large numbers of individuals needed for genetic studies. Here we demonstrate the effectiveness of an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef070e985d72e3c05f92afb5140165e
https://pubmed.ncbi.nlm.nih.gov/29263232
https://pubmed.ncbi.nlm.nih.gov/29263232
Autor:
David A. Hafler, Nicole Cuerdon, Laura R. Glick, Kenneth Vera, Jaime Grutzendler, Salvador D. Fernandez, Phillip L. De Jager, William J. Housley, Mitja Mitrovic, Sasidhar Murikinati, Chris Cotsapas
Publikováno v:
Science Translational Medicine. 7
The transcription factor nuclear factor κB (NFκB) is a central regulator of inflammation, and genome-wide association studies in subjects with autoimmune disease have identified a number of variants within the NFκB signaling cascade. In addition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30919016be731c41a578a967e47355a1
https://doi.org/10.1126/scitranslmed.aaa9223
https://doi.org/10.1126/scitranslmed.aaa9223
Autor:
Maria Cimpean, Keith A. Johnson, Charles C. White, Lori B. Chibnik, Phoebe A. Winn, Julie A. Schneider, Philip L. De Jager, Nicole Cuerdon, Gail Chan, Elizabeth M. Bradshaw, Laura R. Glick, David A. Bennett, Katie J. Ryan, Joseph M. Replogle, Reisa A. Sperling
Publikováno v:
Nature neuroscience
Here, we report results from a protein quantitative trait analysis in monocytes from 226 individuals to evaluate cross-talk between Alzheimer loci. We find that the NME8 locus influences PTK2B and that the CD33 risk allele leads to greater TREM2 expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a423917344b7ddcbe24b327af64643
https://pubmed.ncbi.nlm.nih.gov/26414614
https://pubmed.ncbi.nlm.nih.gov/26414614