Výsledky vyhledávání - "Nicole Cruz-Reyes"

Akademický článek

424 Deciphering the Immune Landscape in Benign Breast Disease: Implications for Risk Stratification and Breast Cancer Prevention

Autor: Matilde Rossi, Nicole Cruz-Reyes, Rob Vierkant, Amy Degnim, Mark Sherman, Derek Radisky

Publikováno v: Journal of Clinical and Translational Science, Vol 8, Pp 126-126 (2024)

OBJECTIVES/GOALS: The objective of our research is to define unique molecular and immune markers in benign breast tissue to better identify women at risk of node-positive breast cancer (BC). The goal of the work is to improve individualized risk asse

Externí odkaz: https://doaj.org/article/fb7f93d05a534ae6840aff9b48ec8832

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Akademický článek

Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion

Autor: Omar L. Gutierrez-Ruiz, Katherine M. Johnson, Eugene W. Krueger, Roseanne E. Nooren, Nicole Cruz-Reyes, Carrie Jo Heppelmann, Tara L. Hogenson, Martin E. Fernandez-Zapico, Mark A. McNiven, Gina L. Razidlo

Publikováno v: Cell Reports, Vol 42, Iss 9, Pp 113042- (2023)

Summary: Amplified lysosome activity is a hallmark of pancreatic ductal adenocarcinoma (PDAC) orchestrated by oncogenic KRAS that mediates tumor growth and metastasis, though the mechanisms underlying this phenomenon remain unclear. Using comparative

Externí odkaz: https://doaj.org/article/9d68ce2bcbb5492f9eed1b1feddc32ac

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Inflammation, Infiltration, and Evasion—Tumor Promotion in the Aging Breast

Autor: Nicole Cruz-Reyes, Derek C. Radisky

Publikováno v: Cancers. 15:1836

Breast cancer is a significant cause of morbidity and mortality in women, with over two million new cases reported worldwide each year, the majority of which occur in post-menopausal women. Despite advances in early detection and treatment, approxima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d21897cd082cfd1d29aa7b60110bc1f1
https://doi.org/10.3390/cancers15061836

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Adenosine A1-Dopamine D1 Receptor Heteromers Control the Excitability of the Spinal Motoneuron

Autor: Vicent Casadó, Sergi Ferré, Yocasta Álvarez-Bagnarol, Marla Rivera-Oliver, Nicole Cruz-Reyes, Christian Ayala-Santiago, Manuel Díaz-Ríos, Stefan Clemens, Estefanía Moreno, Enric I. Canela, Gian Carlo Molina-Castro

Publikováno v: Molecular Neurobiology. 56:797-811

While the role of the ascending dopaminergic system in brain function and dysfunction has been a subject of extensive research, the role of the descending dopaminergic system in spinal cord function and dysfunction is just beginning to be understood.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbdf150e2adcfa6c4c36efa4488cd81f
https://doi.org/10.1007/s12035-018-1120-y

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ATP Synthase c-Subunit Leak Causes Aberrant Cellular Metabolism in Fragile X Syndrome

Publikováno v: Cell

Loss of the gene (Fmr1) encoding Fragile X mental retardation protein (FMRP) causes increased mRNA translation and aberrant synaptic development. We find neurons of the Fmr1-/y mouse have a mitochondrial inner membrane leak contributing to a "leak me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91d768bdd2326fc83721091fd0f5ed3
https://doi.org/10.1016/j.cell.2020.07.008

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Adenosine A

Autor: Marla, Rivera-Oliver, Estefanía, Moreno, Yocasta, Álvarez-Bagnarol, Christian, Ayala-Santiago, Nicole, Cruz-Reyes, Gian Carlo, Molina-Castro, Stefan, Clemens, Enric I, Canela, Sergi, Ferré, Vicent, Casadó, Manuel, Díaz-Ríos

Publikováno v: Molecular neurobiology. 56(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::465496582e9f4e853cee00af50d02f31
https://pubmed.ncbi.nlm.nih.gov/29797183

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Abstract 4162: Prevalence of germline mutations and variants of uncertain significance (VUS) among Hispanics with suspected hereditary colorectal cancer syndromes

Autor: Julyann Pérez-Mayoral, Andrea M. Rosa-Vazquez, Maria Gonzalez-Pons, Nicole Cruz-Reyes, Marcia Cruz-Correa

Publikováno v: Cancer Research. 79:4162-4162

Background: Colorectal cancer (CRC) is one of the leading causes of cancer death in Puerto Rico (PR) and U.S. Approximately 5-10% of all CRC cases are due to hereditary CRC syndromes. Some of the most common hereditary colorectal cancer syndromes inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5747cfed933d8b8a46db86f7e72f0396
https://doi.org/10.1158/1538-7445.am2019-4162

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