Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nicole C. Parsley"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Despite the continuous emergence of multi-drug resistant pathogens, the number of new antimicrobials reaching the market is critically low. Natural product peptides are a rich source of bioactive compounds, and advances in mass spectrometry have achi
Externí odkaz:
https://doaj.org/article/50ea141b9e6c4af38f1902b7990c0e71
Autor:
Jiunn CN Fong, Andrew Rogers, Alicia K Michael, Nicole C Parsley, William-Cole Cornell, Yu-Cheng Lin, Praveen K Singh, Raimo Hartmann, Knut Drescher, Evgeny Vinogradov, Lars EP Dietrich, Carrie L Partch, Fitnat H Yildiz
Publikováno v:
eLife, Vol 6 (2017)
Biofilm formation is critical for the infection cycle of Vibrio cholerae. Vibrio exopolysaccharides (VPS) and the matrix proteins RbmA, Bap1 and RbmC are required for the development of biofilm architecture. We demonstrate that RbmA binds VPS directl
Externí odkaz:
https://doaj.org/article/1598fcb6cbe5419ba956da47cf78b1ac
Publikováno v:
Nat Prod Rep
Covering: Up to July 2020 Ribosomal antimicrobial peptide (AMP) natural products, also known as ribosomally synthesized and post-translationally modified peptides (RiPPs) or host defense peptides, demonstrate potent bioactivities and impressive compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b106275fcc510146a5af19bcbd4fa942
https://doi.org/10.1039/d0np00046a
https://doi.org/10.1039/d0np00046a
Publikováno v:
Methods in enzymology. 663
Antimicrobial peptides (AMPs) are host defense peptides with a range of functions/activities/modes of action that are ubiquitously expressed across all forms of life. Continued discovery of novel AMPs presents exciting opportunities to address evolvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fa90b7bfee5485912b8a79f79ab0d47
https://pubmed.ncbi.nlm.nih.gov/35168797
https://pubmed.ncbi.nlm.nih.gov/35168797
Autor:
Lilian R. Heil, Andrew J. Wommack, Tessa B. Moyer, Dennis Goldfarb, Christine L. Kirkpatrick, Nicole C. Parsley, William A Lefever, Leslie M. Hicks
Publikováno v:
Journal of Natural Products. 82:2744-2753
Traditional medicinal plants are a rich source of antimicrobials; however, the bioactive peptide constituents of most ethnobotanical species remain largely unexplored. Herein, PepSAVI-MS, a mass spectrometry-based peptidomics pipeline, was implemente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e424c934368e434c9f1979be544e6ade
https://doi.org/10.1021/acs.jnatprod.9b00352
https://doi.org/10.1021/acs.jnatprod.9b00352
Publikováno v:
J Am Soc Mass Spectrom
Natural product extracts present inherently complex matrices in which the identification of novel bioactive peptide species is challenged by low abundance masses and significant structural and sequence diversity. Additionally, discovery efforts often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a567aab327715afeba4ac44f9a235b
https://europepmc.org/articles/PMC7816094/
https://europepmc.org/articles/PMC7816094/
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Despite the continuous emergence of multi-drug resistant pathogens, the number of new antimicrobials reaching the market is critically low. Natural product peptides are a rich source of bioactive compounds, and advances in mass spectrometry have achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2b079b007e34624a4650ebe1a00289
https://pubmed.ncbi.nlm.nih.gov/33042872
https://pubmed.ncbi.nlm.nih.gov/33042872
Autor:
Nita H. Salzman, Nicole C. Parsley, Tessa E. Bartges, Steven M. Patrie, Leslie M. Hicks, Christine L. Kirkpatrick, Casey E. Wing, Christopher J. Kristich, Sushma Kommineni
Publikováno v:
Microbial Biotechnology
Summary As current methods for antibiotic drug discovery are being outpaced by the rise of antimicrobial resistance, new methods and innovative technologies are necessary to replenish our dwindling arsenal of antimicrobial agents. To this end, we dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae524b9fd4ebae3ac3e5666eede1e33
http://europepmc.org/articles/PMC6116741
http://europepmc.org/articles/PMC6116741
Autor:
Tessa B, Moyer, Lilian R, Heil, Christine L, Kirkpatrick, Dennis, Goldfarb, William A, Lefever, Nicole C, Parsley, Andrew J, Wommack, Leslie M, Hicks
Publikováno v:
Journal of natural products. 82(10)
Traditional medicinal plants are a rich source of antimicrobials; however, the bioactive peptide constituents of most ethnobotanical species remain largely unexplored. Herein, PepSAVI-MS, a mass spectrometry-based peptidomics pipeline, was implemente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4191e5b71b29eece38754e9b4b3cfd43
https://pubmed.ncbi.nlm.nih.gov/31557021
https://pubmed.ncbi.nlm.nih.gov/31557021
The emergence of rapidly evolving multidrug-resistant pathogens and a deficit of new compounds entering the clinical pipeline necessitate the exploration of alternative sources of antimicrobial therapeutics. Cyclotides revealed in Viola spp. are a cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3d1a10394fbaf8d61ef06a5a10969d
https://europepmc.org/articles/PMC6873112/
https://europepmc.org/articles/PMC6873112/