Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Nicole C Riddle"'
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205867 (2018)
Heterochromatin Protein 1 (HP1) proteins are an important family of chromosomal proteins conserved among all major eukaryotic lineages. While HP1 proteins are best known for their role in heterochromatin, many HP1 proteins function in euchromatin as
Externí odkaz:
https://doaj.org/article/dd4a59d070094a1597ee6365c8d497b8
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185090 (2017)
Obesity is a disease that has reached epidemic proportions in the United States and has prompted international legislation in an attempt to curtail its prevalence. Despite the fact that one of the most prescribed treatment options for obesity is exer
Externí odkaz:
https://doaj.org/article/91f67f6a73ee4b09a868910b22da3947
Autor:
Sean Mendez, Louis Watanabe, Rachel Hill, Meredith Owens, Jason Moraczewski, Glenn C Rowe, Nicole C Riddle, Laura K Reed
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164706 (2016)
Obesity is one of the dramatic health issues affecting developed and developing nations, and exercise is a well-established intervention strategy. While exercise-by-genotype interactions have been shown in humans, overall little is known. Using the n
Externí odkaz:
https://doaj.org/article/27a94ee756664d2b8700c3a46e43d2be
Autor:
Heidi M. Johnson, Nicole C. Riddle
Publikováno v:
Experimental Gerontology, Vol 198, Iss , Pp 112630- (2024)
Exercise is a common strategy for disease prevention or management, including for diabetes and cardiac dysfunction. However, exercise response varies immensely between individuals, and in humans, the same exercise treatment can lead both to positive
Externí odkaz:
https://doaj.org/article/3aa2b99835e34e3b9fe1f1215f050701
Autor:
Nicole C Riddle, Youngsook L Jung, Tingting Gu, Artyom A Alekseyenko, Dalal Asker, Hongxing Gui, Peter V Kharchenko, Aki Minoda, Annette Plachetka, Yuri B Schwartz, Michael Y Tolstorukov, Mitzi I Kuroda, Vincenzo Pirrotta, Gary H Karpen, Peter J Park, Sarah C R Elgin
Publikováno v:
PLoS Genetics, Vol 8, Iss 9, p e1002954 (2012)
Chromatin environments differ greatly within a eukaryotic genome, depending on expression state, chromosomal location, and nuclear position. In genomic regions characterized by high repeat content and high gene density, chromatin structure must silen
Externí odkaz:
https://doaj.org/article/2fa17e0806bd424bb998a29c43376d5e
Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context.
Autor:
Artyom A Alekseyenko, Joshua W K Ho, Shouyong Peng, Marnie Gelbart, Michael Y Tolstorukov, Annette Plachetka, Peter V Kharchenko, Youngsook L Jung, Andrey A Gorchakov, Erica Larschan, Tingting Gu, Aki Minoda, Nicole C Riddle, Yuri B Schwartz, Sarah C R Elgin, Gary H Karpen, Vincenzo Pirrotta, Mitzi I Kuroda, Peter J Park
Publikováno v:
PLoS Genetics, Vol 8, Iss 4, p e1002646 (2012)
The Drosophila MSL complex mediates dosage compensation by increasing transcription of the single X chromosome in males approximately two-fold. This is accomplished through recognition of the X chromosome and subsequent acetylation of histone H4K16 o
Externí odkaz:
https://doaj.org/article/054e3f5a16c34030bd847773adcbd60f
Publikováno v:
Integrative and Comparative Biology. 61:2199-2207
Synopsis Evidence from across the tree of life suggests that epigenetic inheritance is more common than previously thought. If epigenetic inheritance is indeed as common as the data suggest, this finding has potentially important implications for evo
Autor:
Nicole C. Riddle, Justina X. Feng
Publikováno v:
Mammalian Genome. 31:181-195
Maintaining genome stability is essential to an organism's health and survival. Breakdown of the mechanisms protecting the genome and the resulting genome instability are an important aspect of the aging process and have been linked to diseases such
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 4, Pp 1247-1260 (2020)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Exercise is recommended by health professionals across the globe as part of a healthy lifestyle to prevent and/or treat the consequences of obesity. While overall, the health benefits of exercise and an active lifestyle are well understood, very litt
Autor:
John M. Schoelz, Nicole C. Riddle
Publikováno v:
Epigeneticschromatin. 15(1)
In eukaryotes, DNA is packaged into chromatin, which presents significant barriers to transcription. Non-histone chromatin proteins such as the Heterochromatin Protein 1 (HP1) proteins are critical regulators of transcription, contributing to gene re