Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Nicole C Ammerman"'
Autor:
Paul J Converse, Deepak V Almeida, Rokeya Tasneen, Vikram Saini, Sandeep Tyagi, Nicole C Ammerman, Si-Yang Li, Nicole M Anders, Michelle A Rudek, Jacques H Grosset, Eric L Nuermberger
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 8, p e0006728 (2018)
TRIAL REGISTRATION:ClinicalTrials.gov NCT03474198, NCT01659437.
Externí odkaz:
https://doaj.org/article/65826f0602744e5eba53c6c5af40e358
Autor:
Khandra T Sears, Shane M Ceraul, Joseph J Gillespie, Edwin D Allen, Vsevolod L Popov, Nicole C Ammerman, M Sayeedur Rahman, Abdu F Azad
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002856 (2012)
Surface proteins of the obligate intracellular bacterium Rickettsia typhi, the agent of murine or endemic typhus fever, comprise an important interface for host-pathogen interactions including adherence, invasion and survival in the host cytoplasm. I
Externí odkaz:
https://doaj.org/article/84c3396a75874741b90fc8e06fe95039
Autor:
Christer Larsson, Brian Luna, Nicole C Ammerman, Mamoudou Maiga, Nisheeth Agarwal, William R Bishai
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e37516 (2012)
The seven WhiB proteins of Mycobacterium tuberculosis (M.tb) are widely believed to be redox-sensing transcription factors due to their binding of iron-sulfur clusters and similarities to DNA binding proteins. Here, we explored the nature of this hyp
Externí odkaz:
https://doaj.org/article/f813292fbaea4f15b10ff3970fa6056d
Autor:
Geetha Parthasarathy, Shichun Lun, Haidan Guo, Nicole C Ammerman, Deborah E Geiman, William R Bishai
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43429 (2012)
Mycobacterium tuberculosis, the etiologic agent of tuberculosis (TB) possesses at least five genes predicted to encode proteins with NlpC/P60 hydrolase domains, including the relatively uncharacterized Rv2190c. As NlpC/P60 domain-containing proteins
Externí odkaz:
https://doaj.org/article/409938958f6f44809002d0125b65182c
Autor:
Mamoudou Maiga, Nisheeth Agarwal, Nicole C Ammerman, Radhika Gupta, Haidan Guo, Marama C Maiga, Shichun Lun, William R Bishai
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30749 (2012)
Global control of tuberculosis (TB), an infectious disease that claims nearly 2 million lives annually, is hindered by the long duration of chemotherapy required for curative treatment. Lack of adherence to this intense treatment regimen leads to poo
Externí odkaz:
https://doaj.org/article/c45d55d649754762bd933910f63cb276
Autor:
Joseph J Gillespie, Nicole C Ammerman, Sheila M Dreher-Lesnick, M Sayeedur Rahman, Micah J Worley, Joao C Setubal, Bruno S Sobral, Abdu F Azad
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4833 (2009)
Bacterial type IV secretion systems (T4SSs) comprise a diverse transporter family functioning in conjugation, competence, and effector molecule (DNA and/or protein) translocation. Thirteen genome sequences from Rickettsia, obligate intracellular symb
Externí odkaz:
https://doaj.org/article/754633bfd86341148bc9b64fa6f6e0b7
Autor:
Joseph J Gillespie, Magda S Beier, M Sayeedur Rahman, Nicole C Ammerman, Joshua M Shallom, Anjan Purkayastha, Bruno S Sobral, Abdu F Azad
Publikováno v:
PLoS ONE, Vol 2, Iss 3, p e266 (2007)
The genome sequence of Rickettsia felis revealed a number of rickettsial genetic anomalies that likely contribute not only to a large genome size relative to other rickettsiae, but also to phenotypic oddities that have confounded the categorization o
Externí odkaz:
https://doaj.org/article/209ca3092eb74f978ffa3a25037c9fb7
Autor:
Saskia E. Mudde, Jodie A. Schildkraut, Nicole C. Ammerman, Corné P. de Vogel, Jurriaan E.M. de Steenwinkel, Jakko van Ingen, Hannelore I. Bax
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 31, Iss , Pp 345-352 (2022)
ABSTRACT: Objectives: Mycobacterium abscessus is an opportunistic respiratory pathogen in patients with underlying lung disease. It is infamously known for its low treatment success rates because of its resistance to multiple classes of antibiotics.
Externí odkaz:
https://doaj.org/article/64f40b3ee8c649f5b13b24f9e90cc139
Autor:
Steven Dunne, Andrew R. Willmer, Rosemary Swanson, Deepak Almeida, Nicole C. Ammerman, Kathleen A. Stringer, Edmund V. Capparelli, Gus R. Rosania
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 15 (2021)
Clofazimine (CFZ) is a poorly soluble, weakly basic, small molecule antibiotic clinically used to treat leprosy and is now in clinical trials as a treatment for multidrug resistant tuberculosis and COVID-19. CFZ exhibits complex, context-dependent ph
Externí odkaz:
https://doaj.org/article/04a8bb12f7d24456b7b5804dc83f18c1
Autor:
Andrew R. Willmer, Steven Dunne, Rosemary Swanson, Deepak Almeida, Nicole C. Ammerman, Kathleen A. Stringer, Edmund V. Capparelli, Gus R. Rosania
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 17 (2021)
Clofazimine (CFZ) is a weakly basic, small-molecule antibiotic used for the treatment of mycobacterial infections including leprosy and multidrug-resistant tuberculosis. Upon prolonged oral administration, CFZ precipitates and accumulates within macr
Externí odkaz:
https://doaj.org/article/8060cdf7bee147079522fc6df529c075