Výsledky vyhledávání - "Nicole Burkhardt"

Akademický článek

Rickettsia parkeri with a Genetically Disrupted Phage Integrase Gene Exhibits Attenuated Virulence and Induces Protective Immunity against Fatal Rickettsioses in Mice

Autor: Esteban Arroyave, Ilirjana Hyseni, Nicole Burkhardt, Yong-Fang Kuo, Tian Wang, Ulrike Munderloh, Rong Fang

Publikováno v: Pathogens, Vol 10, Iss 7, p 819 (2021)

Although rickettsiae can cause life-threatening infections in humans worldwide, no licensed vaccine is currently available. To evaluate the suitability of live-attenuated vaccine candidates against rickettsioses, we generated a Rickettsia parkeri mut

Externí odkaz: https://doaj.org/article/edb5934affe745a495d2e6f06ddd1688

Zobrazit plný text záznamu

Development and validation of a new method for potential use of Psoriasis Area and Severity Index in teledermatology

Autor: Melinda Gooderham, Helmut Petto, Yves Dutronc, Kurt Gebauer, Nicole Burkhardt, Jason Wu

Publikováno v: The Australasian Journal of Dermatology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a893d3e92ce4fb246fd795529a5d1b19
https://doi.org/10.1111/ajd.13412

Zobrazit plný text záznamu

Multiple Ehrlichia chaffeensis Genes Critical for Its Persistent Infection in a Vertebrate Host Are Identified by Random Mutagenesis Coupled with

Autor: Ying, Wang, Arathy D S, Nair, Andy, Alhassan, Deborah C, Jaworski, Huitao, Liu, Kathleen, Trinkl, Paidashe, Hove, Charan K, Ganta, Nicole, Burkhardt, Ulrike G, Munderloh, Roman R, Ganta

Publikováno v: Infection and immunity. 88(10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::698568c394ab5e6321df4e28adb714e4
https://pubmed.ncbi.nlm.nih.gov/32747600

Zobrazit plný text záznamu

A subset analysis of efficacy and safety outcomes from phase 3 clinical studies of ixekizumab for the treatment of patients with severe plaque psoriasis

Autor: Peter Foley, Nicole Burkhardt, Diana Rubel, Alan Brnabic, Elisabeth Riedl, Lynda Spelman

Publikováno v: The Journal of dermatological treatment. 33(1)

Background: Factors beyond the Psoriasis Area and Severity Index (PASI) contribute to disease severity in psoriasis and potentially affect treatment responses.Objective: This subset analysis of data from two phase 3 clinical studies assessed baseline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24143235380d0347110bb01769929154
https://pubmed.ncbi.nlm.nih.gov/32314628

Zobrazit plný text záznamu

GFPuv-Expressing Recombinant Rickettsia typhi: a Useful Tool for the Study of Pathogenesis and CD8

Autor: Matthias, Hauptmann, Nicole, Burkhardt, Ulrike, Munderloh, Svenja, Kuehl, Ulricke, Richardt, Susanne, Krasemann, Kristin, Hartmann, Till, Krech, Bernhard, Fleischer, Christian, Keller, Anke, Osterloh

Publikováno v: Infection and Immunity

Rickettsia typhi is the causative agent of endemic typhus, a disease with increasing incidence worldwide that can be fatal. Because of its obligate intracellular life style, genetic manipulation of the pathogen is difficult. Nonetheless, in recent ye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28048dfca1923e637bbeb360a17ccc8f
https://pubmed.ncbi.nlm.nih.gov/28289147

Zobrazit plný text záznamu

Maintenance of skin clearance with ixekizumab treatment of psoriasis: Three-year results from the UNCOVER-3 study

Autor: Orin Goldblum, Susan Ball, Nicole Burkhardt, Lluís Puig, Pablo Fernandez-Penas, Pablo Gonzalez, Sandra Philipp, Lotus Mallbris, L. Zhang, Catherine Maari, Craig L. Leonardi

Publikováno v: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Background: Psoriasis is a chronic disease that may require long-term treatment. Ixekizumab (IXE), which is a high-affinity monoclonal antibody that selectively targets interleukin 17A, is an approved therapy for patients with moderate-to-severe plaq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc7a64d377efc2d6e0ae44c8827c7b1
https://doi.org/10.1016/j.jaad.2018.05.032

Zobrazit plný text záznamu

Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia

Autor: Brian Juran, Nicole Burkhardt, Faith M Uckun, Heather E Tibbles, Patricia A. Goodman

Publikováno v: Oncogene. 22:2504-2514

Sequence analysis of the noncoding first exon (exon 1) of the Syk gene demonstrated the presence of a previously cloned CpG island (GenBank #Z 65706). Transient transfection analysis in Daudi cells demonstrated promoter activity (18-fold increase ove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e449d4e9d02f8a89566f6dd0c29a7f
https://doi.org/10.1038/sj.onc.1206313

Zobrazit plný text záznamu

CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity

Autor: Thomas M. Zollner, Yi-Yang Yvonne Li, Khusru Asadullah, Parham Mirshahpanah, Nicole Burkhardt

Publikováno v: Experimental Dermatology. :071019024240001

Psoriasis, atopic dermatitis and allergic contact dermatitis are T-cell-mediated inflammatory skin diseases; chemokine receptors (CCR) 4 and 10 play an important role in the ligand-mediated recruitment of T cells into the skin in mice and humans, spe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86005381ca5e52e27a398a90033cc7f7
https://doi.org/10.1111/j.1600-0625.2007.00630.x

Zobrazit plný text záznamu

Proliferating and differentiating effects of three different growth factors on pluripotent mesenchymal cells and osteoblast like cells

Autor: Marc Luebberstedt, Britt Wildemann, Gerhard Schmidmaier, Nicole Burkhardt, Thomas Vordemvenne

Publikováno v: Journal of Orthopaedic Surgery and Research
Journal of Orthopaedic Surgery and Research, Vol 2, Iss 1, p 27 (2007)

Growth factors are in clinical use to stimulate bone growth and regeneration. BMP-2 is used in long bone and spinal surgery, PDGFbb for the treatment of periodontal defects and children with growth hormone receptor deficiency are treated with IGF-I.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4604ed659a79e0883d375edb3e9aed7e

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání