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pro vyhledávání: '"Nicole Brüggenolte"'
Autor:
Thomas Krieg, Nicole Brüggenolte, Kijawasch Shah Hosseini, Gernot Herrmann, Miriam Grosse Hovest
Publikováno v:
Molecular Biology of the Cell. 17:1758-1767
Cellular senescence is a phenotype that is likely linked with aging. Recent concepts view different forms of senescence as permanently maintained DNA damage responses partially characterized by the presence of senescence-associated DNA damage foci at
Autor:
Nicole Brüggenolte, Kijwasch Shah-Hosseini, Jan Hoffbauer, Gernot Herrmann, Heiko Schober, Primo Schär, Sanja Kais, Margaret Fäsi
Publikováno v:
Nucleic Acids Research
The ligation of DNA double-strand breaks in the process of non-homologous end-joining (NHEJ) is accomplished by a heterodimeric enzyme complex consisting of DNA ligase IV and an associated non-catalytic factor. This DNA ligase also accounts for the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782eb632e04320fd1045d5922c65e6ff
Autor:
Marion-Gabriele Ott, Hans Martin, Dieter Hoelzer, Oliver G. Ottmann, Manuel Grez, Heike Bialek, Heike Merget-Millitzer, Reinhard Seger, Johann Peter Hossle, Nicole Brüggenolte
Publikováno v:
Journal of hematotherapystem cell research. 11(4)
As a single-gene defect in phagocytes, the X-linked form of chronic granulomatous disease (X-CGD) is a disorder potentially amenable to gene therapy by transfer of a functional copy of the gp91(phox) gene into hematopoietic stem cells (HSC). Although