Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicole Bechman"'
Autor:
Marit F. van denBerg, Nicole Bechmann, Hans S. Kooistra, Monique E. vanWolferen, Elpetra P. M. Timmermans‐Sprang, Mirko Peitzsch, Sara Galac
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 5, Pp 2415-2424 (2024)
Abstract Background In humans with pheochromocytomas (PCCs), targeted metabolomics is used to determine the catecholamine phenotype or to uncover underlying pathogenic variants in tricarboxylic acid (TCA) cycle genes such as succinate dehydrogenase s
Externí odkaz:
https://doaj.org/article/d5bceac4709040d7a514d59aecc5b2f3
Autor:
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Mirko Peitzsch, Nicole Bechman, Sameh A Youssef, Alain de Bruin, Elvira R.M. Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl
Female bias is highly prevalent among adrenal cortex hyperplasia and neoplasia, but the reasons behind this phenomenon are poorly understood. In this article, we show that overexpression of the secreted WNT agonist R-spondin-1 leads to ectopic activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af7ad53111dbb9d63ffe0e17814b0559
https://doi.org/10.1101/2022.06.23.497219
https://doi.org/10.1101/2022.06.23.497219
Autor:
Serena Martinelli, Giulia Cantini, Arianna Pia Propato, Daniele Bani, Daniele Guasti, Patrizia Nardini, Laura Calosi, Tommaso Mello, Nicole Bechmann, Giovanna Danza, Fabio Villanelli, Letizia Canu, Mario Maggi, Massimo Mannelli, Elena Rapizzi, Michaela Luconi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The crosstalk between the chromaffin and adrenocortical cells is essential for the endocrine activity of the adrenal glands. This interaction is also likely important for tumorigenesis and progression of adrenocortical cancer and pheochromoc
Externí odkaz:
https://doaj.org/article/abc12b7f1db44c2dbe55a5db66efdd05
Autor:
Bruna Calsina, Elena Piñeiro-Yáñez, Ángel M. Martínez-Montes, Eduardo Caleiras, Ángel Fernández-Sanromán, María Monteagudo, Rafael Torres-Pérez, Coral Fustero-Torre, Marta Pulgarín-Alfaro, Eduardo Gil, Rocío Letón, Scherezade Jiménez, Santiago García-Martín, Maria Carmen Martin, Juan María Roldán-Romero, Javier Lanillos, Sara Mellid, María Santos, Alberto Díaz-Talavera, Ángeles Rubio, Patricia González, Barbara Hernando, Nicole Bechmann, Margo Dona, María Calatayud, Sonsoles Guadalix, Cristina Álvarez-Escolá, Rita M. Regojo, Javier Aller, Maria Isabel Del Olmo-Garcia, Adrià López-Fernández, Stephanie M. J. Fliedner, Elena Rapizzi, Martin Fassnacht, Felix Beuschlein, Marcus Quinkler, Rodrigo A. Toledo, Massimo Mannelli, Henri J. Timmers, Graeme Eisenhofer, Sandra Rodríguez-Perales, Orlando Domínguez, Geoffrey Macintyre, Maria Currás-Freixes, Cristina Rodríguez-Antona, Alberto Cascón, Luis J. Leandro-García, Cristina Montero-Conde, Giovanna Roncador, Juan Fernando García-García, Karel Pacak, Fátima Al-Shahrour, Mercedes Robledo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
The molecular mechanisms underlying metastasis in pheochromocytoma/paraganglioma (mPPGL) remain to be explored. Here, the authors perform genomic and immunogenomic profiling of mPPGL tumors and suggest potential biomarkers for risk of metastasis and
Externí odkaz:
https://doaj.org/article/69b48437dc7349d2ae46afb0ace70885
Autor:
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Nicole Bechmann, Sameh A. Youssef, Alain de Bruin, Elvira R. M. Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/3cf6a8997a32457ab1865951264cbcb2
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Pediatric neural crest-derived adrenal neoplasms include neuroblastoma and pheochromocytoma. Both entities are associated with a high degree of clinical heterogeneity, varying from spontaneous regression to malignant disease with poor outcome. Increa
Externí odkaz:
https://doaj.org/article/c3bab3cb96874cc9a7c81c2b65555774
Autor:
Sara Mellid, Eduardo Gil, Rocío Letón, Eduardo Caleiras, Emiliano Honrado, Susan Richter, Nuria Palacios, Marcos Lahera, Juan C. Galofré, Adriá López-Fernández, Maria Calatayud, Aura D. Herrera-Martínez, María A. Galvez, Xavier Matias-Guiu, Milagros Balbín, Esther Korpershoek, Eugénie S. Lim, Francesca Maletta, Sofia Lider, Stephanie M. J. Fliedner, Nicole Bechmann, Graeme Eisenhofer, Letizia Canu, Elena Rapizzi, Irina Bancos, Mercedes Robledo, Alberto Cascón
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionThe percentage of patients diagnosed with pheochromocytoma and paraganglioma (altogether PPGL) carrying known germline mutations in one of the over fifteen susceptibility genes identified to date has dramatically increased during the last
Externí odkaz:
https://doaj.org/article/c4c5fc8413084893a0bdc6df97e44790
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Adequate oxygen levels are essential for the functioning and maintenance of biological processes in virtually every cell, albeit based on specific need. Thus, any change in oxygen pressure leads to modulated activation of the hypoxia pathway, which a
Externí odkaz:
https://doaj.org/article/42d78ba0bbdc4c308593314db04262a4
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Catecholamine-producing tumors of childhood include most notably neuroblastoma, but also pheochromocytoma and paraganglioma (PPGL). Diagnosis of the former depends largely on biopsy-dependent histopathology, but this is contraindicated in PPGL where
Externí odkaz:
https://doaj.org/article/86e8a7482cbd44789f8942869c033f36
Autor:
Dieter M. Matlac, Katerina Hadrava Vanova, Nicole Bechmann, Susan Richter, Julica Folberth, Hans K. Ghayee, Guang-Bo Ge, Luma Abunimer, Robert Wesley, Redouane Aherrahrou, Margo Dona, Ángel M. Martínez-Montes, Bruna Calsina, Maria J. Merino, Markus Schwaninger, Peter M. T. Deen, Zhengping Zhuang, Jiri Neuzil, Karel Pacak, Hendrik Lehnert, Stephanie M. J. Fliedner
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Paragangliomas and pheochromocytomas (PPGLs) are chromaffin tumors associated with severe catecholamine-induced morbidities. Surgical removal is often curative. However, complete resection may not be an option for patients with succinate dehydrogenas
Externí odkaz:
https://doaj.org/article/341f1888ed96433699e71d363cd1e7e4