Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nicole B. Rockweiler"'
Autor:
Jia Zhou, Renee L. Sears, Xiaoyun Xing, Bo Zhang, Daofeng Li, Nicole B. Rockweiler, Hyo Sik Jang, Mayank N.K. Choudhary, Hyung Joo Lee, Rebecca F. Lowdon, Jason Arand, Brianne Tabers, C. Charles Gu, Theodore J. Cicero, Ting Wang
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background Uncovering mechanisms of epigenome evolution is an essential step towards understanding the evolution of different cellular phenotypes. While studies have confirmed DNA methylation as a conserved epigenetic mechanism in mammalian
Externí odkaz:
https://doaj.org/article/bed260852cb4434482217c71d676d779
Autor:
Nicole B. Rockweiler, Avinash Ramu, Liina Nagirnaja, Wing H. Wong, Michiel J. Noordam, Casey W. Drubin, Ni Huang, Brian Miller, Ellen Z. Todres, Katinka A. Vigh-Conrad, Antonino Zito, Kerrin S. Small, Kristin G. Ardlie, Barak A. Cohen, Donald F. Conrad
Publikováno v:
Science. 380
Postzygotic mutations (PZMs) begin to accrue in the human genome immediately after fertilization, but how and when PZMs affect development and lifetime health remain unclear. To study the origins and functional consequences of PZMs, we generated a mu
Autor:
Nicole B. Rockweiler, Avinash Ramu, Liina Nagirnaja, Wing H. Wong, Michiel J. Noordam, Casey W. Drubin, Ni Huang, Brian Miller, Ellen Z. Todres, Katinka A. Vigh-Conrad, Antonino Zito, Kerrin S. Small, Kristin G. Ardlie, Barak A. Cohen, Donald F. Conrad
Postzygotic mutations (PZMs) begin to accrue in the human genome immediately after fertilization, but how and when PZMs affect development and lifetime health remains unclear. To study the origins and functional consequences of PZMs, we generated a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5143bc4f89dd17e90d42795458e9997
https://doi.org/10.1101/2021.12.20.473199
https://doi.org/10.1101/2021.12.20.473199
Comparative single-cell analysis of biopsies clarifies pathogenic mechanisms in Klinefelter syndrome
Autor:
Jingtao Guo, Katinka Vigh-Conrad, Donald F. Conrad, Nicole B. Rockweiler, Eisa Mahyari, Ana C. Lima, Liina Nagirnaja, James M. Hotaling, Daniel P. Lewinsohn, Douglas T. Carrell, Xichen Nie, Kenneth I. Aston, Alexandra M. Stendahl
Publikováno v:
Am J Hum Genet
Summary Klinefelter syndrome (KS), also known as 47, XXY, is characterized by a distinct set of physiological abnormalities, commonly including infertility. The molecular basis for Klinefelter-related infertility is still unclear, largely because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9089d7cc3ef8dd2c1fe01fa98c6c1c59
https://europepmc.org/articles/PMC8546046/
https://europepmc.org/articles/PMC8546046/
Autor:
Ting Wang, Theodore J. Cicero, Daofeng Li, Rebecca F. Lowdon, Hyung Joo Lee, Jia Zhou, Nicole B. Rockweiler, Mayank N. K. Choudhary, Hyo Sik Jang, C. Charles Gu, Bo Zhang, Renee L. Sears, Xiaoyun Xing, Brianne Tabers, Jason Arand
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-17 (2017)
BMC Genomics
BMC Genomics
Background Uncovering mechanisms of epigenome evolution is an essential step towards understanding the evolution of different cellular phenotypes. While studies have confirmed DNA methylation as a conserved epigenetic mechanism in mammalian developme
IntroductionOncogenic somatic mutations confer proliferative advantage and undergo positive clonal selection. We developed software and applied new analytical approaches to identify: (1) somatic mutations in diverse tissues, (2) somatically mutated g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a87bcb0a1c3a1b0e84ee493c5195c41
https://doi.org/10.1101/396739
https://doi.org/10.1101/396739
Autor:
Savita Sankar, Kristen L. Kroll, Nicole B. Rockweiler, Bo Zhang, Dhananjay Yellajoshyula, Bryan Teets
Publikováno v:
Scientific Reports
Neural cell fate acquisition is mediated by transcription factors expressed in nascent neuroectoderm, including Geminin and members of the Zic transcription factor family. However, regulatory networks through which this occurs are not well defined. H
Autor:
Christina M. Taylor, Nicole B. Rockweiler, Cassie Liu, Garland R. Marshall, Oleg G. Kisselev, Anna-Karin Tunemalm, Loryn Rikimaru
Publikováno v:
Chemical Biology & Drug Design. 75:325-332
G-protein coupled receptors play an essential role in many biological processes. Despite an increase in the number of solved X-ray crystal structures of G-protein coupled receptors, capturing a G-protein coupled receptor in its activated state for st
Publikováno v:
IEEE Transactions on Dielectrics and Electrical Insulation. 16:1251-1258
The structure of eukaryotic cells is maintained by a network of filamentous actin anchored subjacently to the plasma membrane. This structure is referred to as the actin cortex. We present a locally constrained surface tension model for electroporati
Autor:
Daofeng Li, Nicole B. Rockweiler, Rebecca F. Lowdon, Pamela A. F. Madden, Bo Zhang, Ting Wang, Ivan Smirnov, Joseph F. Costello, Xin Zhou, Renee L. Sears
Publikováno v:
Nature biotechnology. 33(4)