Routine Genetic Testing of Germline Breast Cancer Susceptibility ─ Challenges and Opportunities

Autor: Cornelia Leo, Kathrin Schwedler, Rosaria Condorelli, Nicole Bürki, Jens Huober, Khalil Zaman, Christian Kurzeder, Marcus Vetter

Publikováno v: healthbook TIMES. Oncology Hematology, Vol 17, Iss 3 (2023)

Information on germline BRCA (g*BRCA*) 1/2 pathogenic or likely pathogenic mutations has predictive value for response to platinating agents and poly(ADP-ribose) polymerase inhibitors (PARPi) and survival outcomes of breast cancer (BC) patients. In t

Externí odkaz: https://doaj.org/article/cf049c079418491f9bbe809dabc7ebb9

Intention to Inform Relatives, Rates of Cascade Testing, and Preference for Patient-Mediated Communication in Families Concerned with Hereditary Breast and Ovarian Cancer and Lynch Syndrome: The Swiss CASCADE Cohort

Autor: Mahesh, Sarki, Chang, Ming, Souria, Aissaoui, Nicole, Bürki, Maria, Caiata-Zufferey, Tobias Ephraim, Erlanger, Rossella, Graffeo-Galbiati, Karl, Heinimann, Viola, Heinzelmann-Schwarz, Christian, Monnerat, Nicole, Probst-Hensch, Manuela, Rabaglio, Ursina, Zürrer-Härdi, Pierre Olivier, Chappuis, Maria C, Katapodi, On Behalf Of The Cascade Consortium

Publikováno v: Cancers; Volume 14; Issue 7; Pages: 1636
Sarki, Mahesh; Ming, Chang; Aissaoui, Souria; Bürki, Nicole; Caiata-Zufferey, Maria; Erlanger, Tobias Ephraim; Graffeo-Galbiati, Rossella; Heinimann, Karl; Heinzelmann-Schwarz, Viola; Monnerat, Christian; Probst-Hensch, Nicole; Rabaglio, Manuela; Zürrer-Härdi, Ursina; Chappuis, Pierre Olivier; Katapodi, Maria C (2022). Intention to Inform Relatives, Rates of Cascade Testing, and Preference for Patient-Mediated Communication in Families Concerned with Hereditary Breast and Ovarian Cancer and Lynch Syndrome: The Swiss CASCADE Cohort. Cancers, 14(7) MDPI AG 10.3390/cancers14071636

Cascade screening for Tier 1 cancer genetic conditions is a significant public health intervention because it identifies untested relatives of individuals known to carry pathogenic variants associated with hereditary breast and ovarian cancer (HBOC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0caa0c80158f6b0d9318a6c1160d9903

Genetic Literacy and Communication of Genetic Information in Families Concerned with Hereditary Breast and Ovarian Cancer: A Cross-Study Comparison in Two Countries and within a Timeframe of More Than 10 Years

Autor: Carla Pedrazzani, Chang Ming, Nicole Bürki, Maria Caiata-Zufferey, Pierre O. Chappuis, Debra Duquette, Karl Heinimann, Viola Heinzelmann-Schwarz, Rossella Graffeo-Galbiati, Sofia D. Merajver, Kara J. Milliron, Christian Monnerat, Olivia Pagani, Manuela Rabaglio, Maria C. Katapodi

Publikováno v: Cancers; Volume 13; Issue 24; Pages: 6254
Cancers
Pedrazzani, Carla; Ming, Chang; Bürki, Nicole; Caiata-Zufferey, Maria; Chappuis, Pierre O; Duquette, Debra; Heinimann, Karl; Heinzelmann-Schwarz, Viola; Graffeo-Galbiati, Rossella; Merajver, Sofia D; Milliron, Kara J; Monnerat, Christian; Pagani, Olivia; Rabaglio, Manuela; Katapodi, Maria C (2021). Genetic Literacy and Communication of Genetic Information in Families Concerned with Hereditary Breast and Ovarian Cancer: A Cross-Study Comparison in Two Countries and within a Timeframe of More Than 10 Years. Cancers, 13(24) MDPI AG 10.3390/cancers13246254
Cancers, Vol 13, Iss 6254, p 6254 (2021)

Simple Summary This cross-study comparison uses data collected over 10 years from families living in the US and in Switzerland in order to compare genetic literacy between individuals who had genetic counselling for hereditary breast/ovarian cancer (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3989910a99032d02d7da6cb90d65dbf7

Examining information-seeking behavior in genetic testing for cancer predisposition: A qualitative interview study

Autor: Bettina M. Zimmermann, David Shaw, Insa Koné, Bernice Simone Elger, Nicole Bürki, Manuela Rabaglio, Julia Fanderl

Publikováno v: Patient Education and Counseling, 104(2), 257-264. Elsevier Ireland Ltd

Objective: This study aims to assess information needs and information sources and seeks to illustrate what at-risk individuals consider motivators of and barriers to information-seeking before and after genetic testing for cancer predisposition.Meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f10b49410f667fd3ccc5ac4cc51d17b
https://pubmed.ncbi.nlm.nih.gov/32988685

S143. Steroid Hormone Analysis of Retrospective Maternal Hair and Newborn Nail Samples Indicate Effects of Prenatal Stress on Postpartum Well-being of Mother and Offspring

Autor: Thorsten Mikoteit, Nicole Bürki, Martin Hatzinger, Irene Hösli, Edith Holsboer-Trachsler, Jennifer Kurath, Serge Brand, Marion Tegethoff, Gunther Meinlschmidt

Publikováno v: Biological Psychiatry. 83:S403-S404

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62464ccf6dbf0df61c547394f81a42ef
https://doi.org/10.1016/j.biopsych.2018.02.1035